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Super Strength Substance Approaching Human Trials

kdawson posted more than 4 years ago | from the radioactive-spider-bite dept.

Biotech 425

kkleiner writes "You may remember Liam Hoekstra, the baby apparently born without the myostatin gene, and consequently sporting 40% more skeletal muscle than his peers. Using gene therapy, NCH scientists have been able to get follistatin (a myostatin blocker) to promote phenomenal muscle growth in macaque monkeys. NCH is now working with the FDA to perform the preliminary steps necessary for a human clinical trial. Is this the prelude to a super-strength gene therapy for all of us?"

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425 comments

Classic Super Villain Birth (4, Funny)

eldavojohn (898314) | more than 4 years ago | (#30372270)

Is this the prelude to a super-strength gene therapy for all of us?

No, the clinical trials will begin but one of the test subjects will realize that they are now stronger than his fellow man and the only thing keeping him a cut above the rest is the drug. So he (or she, both sexes are equally evil) will taint the other subjects' follistatin with cyanide, killing them all. Then the super villain transformation into The Sinister Strength will be complete and they will emerge from the carnage at the clinic to hoard all the remaining follistatin. We have only one hope, that our hero Liam Hoekstra arrives on the scene early enough to put an end to The Sinister Strength ... refresh Slashdot next week to find out.

Re:Classic Super Villain Birth (5, Funny)

HBoar (1642149) | more than 4 years ago | (#30372342)

Unless, of course, we manage to capture the super humans in time and send them all into space in suspended animation on a cargo ship.

Re:Classic Super Villain Birth (0)

Anonymous Coward | more than 4 years ago | (#30372376)

Vee!

Re:Classic Super Villain Birth (2, Funny)

Kratisto (1080113) | more than 4 years ago | (#30372594)

No, no, this will never happen. The scientists noted that one of the side effects of the treatment was green skin. I think we know where that leads.

Re:Classic Super Villain Birth (0)

Anonymous Coward | more than 4 years ago | (#30372672)

To promotional deals with Green Giant brand canned foods? :D

Re:Classic Super Villain Birth (5, Funny)

Ryvar (122400) | more than 4 years ago | (#30372604)

If I refresh Slashdot next week the only thing I'm going to see is a dupe of this story.

Re:Classic Super Villain Birth (2, Interesting)

bmxeroh (1694004) | more than 4 years ago | (#30372828)

You joke, but your image of abuse is probably very real, depending on the availability. I mean, your always going to have people that will abuse it no matter what, but imagine if you would if this falls in line with other optional surgeries and procedures. Not happy with how you look? How about some gene therapy to fix your body image? Do we really need angry people suddenly developing 40% more muscle mass? People are assholes enough, but now there's no question they can beat the crap out of me if they get angry. On the flip side, this sounds like it could work miracles for some with real problems.

Obvious (?) question (1)

Dice (109560) | more than 4 years ago | (#30372294)

And what would we do with this super strength? Personally, the heaviest thing I ever need to lift is the occasional DB server.

Re:Obvious (?) question (4, Insightful)

hort_wort (1401963) | more than 4 years ago | (#30372372)

This is my reaction too. Also, what is the cost of having to maintain all these muscles? Do you have to eat more than the normal person? Do you lose all your fine motor control?

The human is the best animal in the brain department. Why don't they try to improve what we're good at? Why compete with the Gorilla?

Re:Obvious (?) question (0)

Anonymous Coward | more than 4 years ago | (#30372400)

I think the applications are obvious...

No doubt these super humans would need more calories to function at a basic level

Re:Obvious (?) question (5, Funny)

Conspiracy_Of_Doves (236787) | more than 4 years ago | (#30372444)

We would need to eat a lot more than the normal human needs to.

The diet of the average American should just about cover it.

Re:Obvious (?) question (3, Insightful)

benjamindees (441808) | more than 4 years ago | (#30373028)

That's true but unfortunately you would probably have to eat a lot more protein. The diet of the average American is heavily weighted towards sugars, fats and starches since that's what our overdeveloped brains tell us we need. So we have naturally used those brains to develop mechanized agriculture that can produce those foods most efficiently. This has basically turned us into highly-intelligent blobs.

Re:Obvious (?) question (4, Insightful)

digitalunity (19107) | more than 4 years ago | (#30372498)

Muscle burns more energy than fat, both at rest and during physical activity.

An effective oral myostatic blocker would enable a lot of people to reduce their body fat levels with minimal lifestyle change.

For those who are severely obese, this would be a godsend since for many of them they weigh so much and have such small muscle mass that physical activity can be dangerous.

Re:Obvious (?) question (1)

noric (1203882) | more than 4 years ago | (#30372664)

very interesting point.. who knew the secret to weight loss might be a fitness drug ;)

Re:Obvious (?) question (0)

Anonymous Coward | more than 4 years ago | (#30372740)

Maybe you should rethink that for just a moment. If you weigh 400lbs and are able to move under your own power don't you think that you would by definition have more muscle mass than the guy next to you who weighs 120lbs and does no exercise as well. At least you should be able to push with your legs with a force greater than 400lbs in order to move.

Re:Obvious (?) question (1)

geekoid (135745) | more than 4 years ago | (#30372792)

It would also be a god send to us 40 something with a pot belly thatw ant to look like they did in high school without the pesky being active all the time part.

Re:Obvious (?) question (4, Insightful)

compro01 (777531) | more than 4 years ago | (#30372502)

The human is the best animal in the brain department

Which we are using to (attempt to) become better than everything at everything.

Re:Obvious (?) question (1, Redundant)

maxume (22995) | more than 4 years ago | (#30372386)

I would guess the researchers are interested in treating people with severely decreased muscle mass (for whatever reason; genetics, disease, bedridden, space travel, etc.).

Re:Obvious (?) question (4, Insightful)

gandhi_2 (1108023) | more than 4 years ago | (#30372532)

I would guess the researchers are interested in the multi-billion-dollar weight-lifting supplement market.

There...

Re:Obvious (?) question (5, Informative)

PotatoFarmer (1250696) | more than 4 years ago | (#30372676)

No need to guess, from TFA:

"The National Children's Hospital interest in myostatin is not to create super strong children, but to help those children whose muscles have already atrophied. Muscular Dystrophy (MD) affects thousands of children in the US who slowly lose muscle and rarely survive into adulthood. Follistatin gene therapy could serve as a method to extend their lives or perhaps even reverse the symptoms of their conditions. Likewise, the eldery are susceptible to several diseases that lead to a loss of muscle strength and coordination. By blocking myostatin, we may all be able to live with the strength of our youth even as we age into our 80s."

Re:Obvious (?) question (5, Interesting)

timeOday (582209) | more than 4 years ago | (#30372714)

I'm sure you're right, but I'll bet the main commercial application will be found in super-meaty chickens and cows.

Re:Obvious (?) question (1)

Sulphur (1548251) | more than 4 years ago | (#30372980)

I'll bet the main commercial application will be found in super-meaty chickens and cows.

That is assuming that you can catch and kill the chickens and cows.

Re:Obvious (?) question (2, Insightful)

geekoid (135745) | more than 4 years ago | (#30372440)

first off, you would have 40% more muscle with no effort. The ladies will be a callin'

Second off, you cold intimidate someone else to lift the DB server

Re:Obvious (?) question (5, Interesting)

cl0ckt0wer (973067) | more than 4 years ago | (#30372442)

It could cure obesity: more muscles increases your resting metabolic rate. Just increase muscle mass to the point where your digestive tract is overwhelmed, and you start burning fat, no matter what you eat. Kind of like the movie "thinner", but this one would be called "muscular". That brings up interesting questions about what happens when your musculo-skeletal system and your nervous system start fighting for calories. The stereotypical big dumb guy? And isn't this gene therapy, where one shot changes your DNA for life? Culturally, this will hit the fitness industry like a bombshell. Billions are spent annually on looking "ripped". Here's the real deal. Pretty soon, you won't get laid without it.

Re:Obvious (?) question (5, Funny)

Locke2005 (849178) | more than 4 years ago | (#30372514)

Pretty soon, you won't get laid without it. I think I speak for many slashdotters when I ask, "how is that any different from my current situation?"

Re:Obvious (?) question (0)

failedlogic (627314) | more than 4 years ago | (#30372860)

So are if you're an old man, you'll have to lift weights with your dick and take Viagra impress the ladies.

Re:Obvious (?) question (0)

Anonymous Coward | more than 4 years ago | (#30372652)

It could cure obesity: more muscles increases your resting metabolic rate.

Muscles turn into fat when you quit training. Add some alcoholic beverages in the mix and it's the opposite of the cure for obesity.

Re:Obvious (?) question (1)

DigiShaman (671371) | more than 4 years ago | (#30372506)

If I had to choose one spot to have this therapy applied, it would be my lower back. Having pulled it every other month is getting annoying.

Re:Obvious (?) question (5, Insightful)

wizardforce (1005805) | more than 4 years ago | (#30372516)

I would imagine that this would be incredibly useful to those with muscle wasting diseases.

Re:Obvious (?) question (5, Interesting)

Antique Geekmeister (740220) | more than 4 years ago | (#30372608)

And astronauts: the muscular atrophy they experience at zero gee is quite profound, and is a real risk to extended space station or possible Mars missions.

Re:Obvious (?) question (1, Insightful)

Anonymous Coward | more than 4 years ago | (#30372786)

Isn't the osteoporosis one of the other big problems? Would that mean that when they got back to Earth their bones could break from too much exertion by their extra large muscles?

Re:Obvious (?) question (1)

phantomcircuit (938963) | more than 4 years ago | (#30372934)

Actually it is the loss of bone mass that is really dangerous. In fact increasing muscle mass without increasing bone density would probably be FATAL to astronauts.

Re:Obvious (?) question (1)

Labcoat Samurai (1517479) | more than 4 years ago | (#30372530)

This is a long shot, but maybe this would level the playing field in terms of physical appearance. Then it would all come down to money and personality, and surely Slashdot readers would benefit.

I wouldn't get my hopes too high just yet, though.

Re:Obvious (?) question (0)

Anonymous Coward | more than 4 years ago | (#30372766)

They've got a pill to give you muscles, but they still don't have a pill to cure your particular brand of ugly.

Re:Obvious (?) question (1)

svunt (916464) | more than 4 years ago | (#30373034)

Off the top of my head, I could do a lot on foot that I currently need a car for, like carrying a tonne of groceries home from the shop. I could move house without trolleys - and more importantly without back injuries, with more muscle supporting my spine. I'd also be faster, so I could avoid otherwise fatal accidents with falling pianos. I could bang my fat wife standing up for once (disclaimer: I have no fat wife), pull my kids out of a flaming wreckage several years longer into their own lives...the list goes on. Your sedentary lifestyle is not normal, or healthy.

Super-strength Macaque monkeys (0, Redundant)

noidentity (188756) | more than 4 years ago | (#30372324)

scientists have been able to get follistatin (a myostatin blocker) to promote phenomenal muscle growth in macaque monkeys

I, for one, welcome our soon-to-be Macaque monkey overlords with my open puny-muscled arms.

Super mutants going cheap (2, Insightful)

Qlither (1614211) | more than 4 years ago | (#30372334)

Well damn, now no one will buy my super mutants if they can be one :(. >MadDoc

Now I'll never finish my fortress! (5, Informative)

Anonymous Coward | more than 4 years ago | (#30372348)

My dwarves are going to be 100% more terrified when the monkeys have super strength!

Re:Now I'll never finish my fortress! (1)

smartaleq (905491) | more than 4 years ago | (#30372870)

Urist Stormfist cancels drink: Interrupted by Macaque Hulk.
Urist Stormfist has been struck down.

Just wait until they get to the elephants... (0)

Anonymous Coward | more than 4 years ago | (#30373036)

If you think that's bad, just wait until they get it to work on the elephants. I mean, after what happened to the fortress of Boatmurdered, it's like you need an Orbital Magma Cannon just to survive. And God help you when those damn fish show up...

It's just a pity that you can't really use the elf toilet setup (where you wall them in, build a roof over them, then flood out and drown the elves, with a nice drain to flush things out afterwards) on the monsters of the Glowing Pit...

No. (0)

Anonymous Coward | more than 4 years ago | (#30372394)

No. It will be used clinically for people who have muscle growth problems. For athletes, it will remain a banned substance.

Re:No. (1)

Locke2005 (849178) | more than 4 years ago | (#30372484)

Riiiiiiight... 'cause there are no documented cases of athletes EVER using banned substances!

In this case, it's not even a banned substance, it's a banned gene therapy treatment -- at least it should be easy to detect. Guess we need to start rewriting the rules now to deal with athletes with modified DNA.

Helpful for the Obese... (1)

jameskojiro (705701) | more than 4 years ago | (#30372448)

One of the problems with wanting to lose weight is by the time you become a large tub, you no longer have enough muscle to move around and exercise. Now you can take this drug, have enough power to start working out and not feel like you are dying when you are starting out, which may increase the positive feedback effect.

Re:Helpful for the Obese... (1)

furbearntrout (1036146) | more than 4 years ago | (#30372898)

In my experience, the problem (with exercise) is the joints, not the muscles. In this case, the increase in BMR [wikipedia.org] is more significant.

Fastest way to burn calories is to gain musclemass (3, Insightful)

netsavior (627338) | more than 4 years ago | (#30372452)

so is this the new diet drug? Americans already take in too many calories, it would be very trans-human and very cool if we just altered our muscle mass instead of shrinking our calorie intake.

Re:Fastest way to burn calories is to gain musclem (1)

geekoid (135745) | more than 4 years ago | (#30372758)

That would be awesome.

Also, getting modded so you absorb a small % of fat.
SO many great ways we could modify our bodies. If only I can be modded to generate electricity for my mobile devices*.

Please spare me the obvious matrix reference.

Um, there are not-unforseen problems (3, Insightful)

Jack9 (11421) | more than 4 years ago | (#30372456)

We have a world food distribution/shortage problem as it is. Imagine SUPER STRONG STARVING Humans.

http://www.ashtreehill.com/the-hungry.html [ashtreehill.com]

Re:Um, there are not-unforseen problems (1)

maxume (22995) | more than 4 years ago | (#30372496)

I am imagining them breaking down the muscle mass for energy and becoming super weak starving humans.

Re:Um, there are not-unforseen problems (1)

FooAtWFU (699187) | more than 4 years ago | (#30372528)

The food supplies of those who are likely to consume this drug aren't really strongly related to those of the world's starving, for better or worse. At least not at the moment.

Re:Um, there are not-unforseen problems (2, Insightful)

Locke2005 (849178) | more than 4 years ago | (#30372564)

And you thought you had problems with bullies stealing your lunch money before!

Re:Um, there are not-unforseen problems (0, Insightful)

Anonymous Coward | more than 4 years ago | (#30372650)

We have a world food distribution/shortage problem as it is. Imagine SUPER STRONG STARVING Humans.

http://www.ashtreehill.com/the-hungry.html [ashtreehill.com]

*We* do? Citation needed. Definition of "we" needed. I don't have a food shortage. No one I personally know does either. Crazy homeless people don't count. Why? Because of that little theory called "evolution." Natural selection should kill you off if you are too stupid to obtain food, or too stupid to follow the heard, or too stupid to cultivate crops. I doubt we would have a food shortage if all you evil bastards stopped donating to starving kids in Africa charities.

Look people, they had their chance just like ever single other lineage. They grew incapable of sustaining their own lives, the burden is not on us to keep them alive, and THAT is what is causing a food shortage. If they are incapable of obtaining food (through hunting, gathering, or you know, CROP CULTIVATION) they should all starve to death so the rest of us have more resources.

It's disgusting to see people actual donate to the starving kids in Africa funds because it allows those specific Africans to continue living off handouts in disease infested squalor, rather than migrating to an area capable of sustaining their very own lives. Shame on you charity corporations for preserving and perpetuating human suffering.

~80% Increase (1)

jesusfr3Ak (1693850) | more than 4 years ago | (#30372490)

Imagine being able to go from 100 kilos to 180 - a pretty significant gain. I don't see how the likes of the Army or Marines could pass something like this up.

Funny, but... (1, Funny)

Anonymous Coward | more than 4 years ago | (#30372512)

...why are all of these rated so Low? The Score dude doesn't appreciate good humor?

Missing the point (0)

Anonymous Coward | more than 4 years ago | (#30372526)

The odds are against general use of the treatment in humans. What about domestic animals though? 40 to 60lb turkeys or 2,500lb cattle. Chickens the size of turkeys? Anything to squeeze another buck out of domestic livestock.

consequences (4, Interesting)

fred fleenblat (463628) | more than 4 years ago | (#30372560)

Seems like there is probably a reason we have myostatin and if you disable it, other health problems may result. We're just don't know what they are yet.

Further, it seems like the people most interested in taking this drug would be bodybuilders who already have a low body fat percentage...they have little fat to burn and now this reduces the ability to metabolize their muscle tissue. I could foresee that a small medical problem involving the digestive tract could turn into a complete crisis if they cannot get the energy they need to fight an infection from their own tissues when they need it most.

Re:consequences (5, Insightful)

John Hasler (414242) | more than 4 years ago | (#30372732)

> Seems like there is probably a reason we have myostatin and if you disable
> it, other health problems may result.

You'll need to eat more.

And no, that isn't a joke. There is strong evolutionary pressure for nutritional efficiency. Carrying around muscles you don't need uses up calories you could have used to live through the drought. Not a problem now for most humans, but it really mattered for all animals until fairly recently.

Re:consequences (1)

crazybit (918023) | more than 4 years ago | (#30373044)

There is strong evolutionary pressure for nutritional efficiency. Carrying around muscles you don't need uses up calories you could have used to live through the drought. Not a problem now for most humans, but it really mattered for all animals until fairly recently.

Yeah? so if a single human would have been able to kill a Mamut with his bare hands it wouldn't have been considered as an evolutionary advantage? If they could have built a house by themselves using 1 ton stones by himself? how about ripping the head off saber tooth tigers?

I don't think it's an evolutionary issue, as parent says, we don't know what we will break in the long term if humans start using this drug. Maybe each generation will loose 10% of it's IQ, which will be hard to measure in monkeys and mice.

Re:consequences (1)

dbIII (701233) | more than 4 years ago | (#30372784)

Seems like there is probably a reason we have myostatin and if you disable it

There is a theory that early human hunters would spear a big, strong, fast furry critter and then just keep following the thing at a steady pace until it collapsed from exhaustion. We seem to be built for the long run instead of the short sprint.
Personally I'm looking for the genetic modification that lets me get by on about an hour of sleep a night.

Re:consequences (3, Interesting)

arb phd slp (1144717) | more than 4 years ago | (#30372858)

I think I read something (in the same article as I read about the endurance hunting you reference) that humans already deal with sleep deprivation better than most of the animal kingdom. It's one of the reasons that endurance hunting works for us but other predators can't do it.
I don't think knowledge workers like slashdotters would want to go without sleep long-term. Sleep is when learning happens (moving memory traces from short-term into long-term memory). Even if you could, why would you want to kick your cognition in the teeth like that?

features, not side effects (1)

mevets (322601) | more than 4 years ago | (#30372960)

For example I take anabolic steroids to shrink my testicles, not gain muscle mass. Works like a charm, I'm no longer embarrassed at the beach.

Super Soldiers? (4, Insightful)

SpuriousLogic (1183411) | more than 4 years ago | (#30372636)

Seriously, if we had soldiers that were 40% stronger, that would be a huge advantage. They could carry more gear, or more powerful weapons, and be considerably more effective than "normal" soldiers. The Air Force already has done trials on drugs that allow pilots to stay awake for days without side effect(a little tangent here - I'm surprised IT departments have not done this yet for Admins and programmers). You have got to think the Army and Marines would be VERY interested in this if it is viable.

Re:Super Soldiers? (4, Interesting)

isa-kuruption (317695) | more than 4 years ago | (#30372744)

The military has been working on what I'd call troop supplement vehicles. Basically, they are small cart vehicles able to carry a couple thousand pounds. They can follow a soldier around, or manually controlled to perform delivery tasks during a fire fight. Beats a 40% increase in strength by far.

Re:Super Soldiers? (0)

Anonymous Coward | more than 4 years ago | (#30372826)

Um, So the Military can't have both. Troop supplement vehicles sound great. So does being able to pick up the stuff on the vehicle should, I don't know someone blow one of it's legs off. Other then unforeseen side effects I can't see why we wouldn't use this drug. The man side effect seems to be needs more food then usual. Also the stronger the muscles the easier it will be to break your bones and tendons If they are not also strengthened up.

Re:Super Soldiers? (2, Informative)

JoeMerchant (803320) | more than 4 years ago | (#30372800)

Did you read the part about eating 6 meals a day and still not thriving? These "supermen" will have a super intensive logistical support network, not just to feed them but also to take care of their other medical quirks.

Re:Super Soldiers? (0)

Anonymous Coward | more than 4 years ago | (#30372926)

Right, from the previous article (http://www.ctv.ca/servlet/ArticleNews/story/CTVNews/20070530/strong_toddler_070530?hub=WFive)

"He's hungry for a full meal about every hour because of his rapid metabolism," Dana Hoekstra said. "He's already eating me out of house and home."

Obviously has a drawback there.

Re:Super Soldiers? (2, Interesting)

sexconker (1179573) | more than 4 years ago | (#30372866)

The human brain operates on around a 22.5 hour cycle. Sleep, the sun, diet, and routine are enough to compensate for the 1.5 hour difference between our wired cycle and the Earth''s rotational cycle.

The Navy operates submarines (shift-wise) on a 16-hour cycle. And without the sun, that shit gets fucked up enough as it is.

The solution? Nothing - power through, boys!

Re:Super Soldiers? (0)

Anonymous Coward | more than 4 years ago | (#30372908)

Admins and programmers already "juice" on caffeine pills, power drinks, caffeine shampoos, cocaine, meth, coffee, and masturbating before in the morning before/during the drive to work.

Re:Super Soldiers? (5, Funny)

Rogerborg (306625) | more than 4 years ago | (#30372930)

Since the US adopted a policy of only fighting wars against tiny Orientals or half-starved Arabs, they're already 40% stronger than the opposition.

Re:Super Soldiers? (1)

Chris Burke (6130) | more than 4 years ago | (#30372986)

(a little tangent here - I'm surprised IT departments have not done this yet for Admins and programmers).

They pretty much do, by only drug testing prior to employment, encouraging or outright demanding their employees work extreme hours, and turning a blind eye to whatever the employee may choose to do in order to comply. Granted, coke and meth are hardly "without side effect", but IT departments hardly have the resources of the Air Force to create experimental drugs, and they let you get the job done for a while at least, with the plus side that the employer can't and thus doesn't have to provide them.

Help for the Elderly? (4, Insightful)

LifesABeach (234436) | more than 4 years ago | (#30372638)

One group of people that might take advantage of this treatment would be the elderly. Diminishing muscle mass is a major issue. I use to joke about my Mother-In-Law being mean enough to hunt Bear with a Switch; some how that doesn't seem funny any more.

Space program application (1, Interesting)

Anonymous Coward | more than 4 years ago | (#30372674)

There's a major application for this research in space travel. One of the major issues with long duration space missions is muscle atrophy. This could provide assistance in maintaining muscle mass on trips to and from Mars, as well as long duration Moon missions. Not to mention the potential eventual colonization of said worlds.

Use for astronaunts? (0)

Anonymous Coward | more than 4 years ago | (#30372726)

Could this be used to help fix the problem astronaunts have of losing muscle mass in weightlessness?

That's it. (1)

Korey Kaczor (1345661) | more than 4 years ago | (#30372778)

Time to stock up on molotovs and pills for my safe room.

Re:That's it. (0, Offtopic)

sexconker (1179573) | more than 4 years ago | (#30372892)

Grabbin' peeels!

The new survivors suck. Bill and Zoey forever.

Hell, even Francis and Louis are better than any of the shitty fuckers we got this time around.

The way of things... (2, Insightful)

WheelDweller (108946) | more than 4 years ago | (#30372816)

Ya know, I've seen A LOT of announcements here, like the ever-popular flexible displays that are always "just around the corner" since about 1996, but there's a reality about things like this.

1. It's not a guaranteed arrival. Nothing in here says you get, for example, to keep the use of your penis, or that you'll be able to take the medicine AND sleep at night.

2. This won't likely start a new race of uber-supermen as one might guess. What it *will* do is complicate Oylmpic candidates and other sport.

I hate to be Slashdot's wet blanket, but I'm an old man, and I've seen a LOT of these things come to nothing.

Ahhhh (0)

Anonymous Coward | more than 4 years ago | (#30372846)

So this is what kicks off the Zombie Apocalypse...

Skeptical about significant increase Caloric Needs (5, Informative)

axjms (167179) | more than 4 years ago | (#30372864)

While true that muscle burns more calories at rest and that a more heavier, more muscular person needs more calories than a lighter, thinner person I think most slashdotters are overestimating the effects. I mean the little hulk kid is growing too. All toddlers eat like little monsters. Anyway, a pound of muscle at rest burns 35 to 50 calories a day, so up to 500 calories for ten pounds of new muscle per day. So lets do some quick math. The average American male is made up of about 42% skeletal muscle, which at 185 lbs that is roughly 75 pounds of muscle. If you increase the muscle mass by 40% (Yes, I RTFA) that is about 30 lbs of new muscle. Pretty awesome when you think about it, but that still only burns an extra 1500 calories a day max. Most Americans overeat that amount anyway. I don't think anyone would be starving, they would just be harder and fitter. A big mac has over 500 calories to put that into perspective.

I think a more interesting question is what do you do if this is readily available, cheap and easy to use? Would you do it? What if you are an active amateur cyclist working your way up the local ranks? They guys are gonna love you coming in with your extra 30 lbs of muscle and storm by them up the local hill. Do we start over with all the record books? This isn't exactly roids but it isn't exactly a tough training plan that you earned your fitness with either.

Less Captain America, more Marshal Law (1)

BearRanger (945122) | more than 4 years ago | (#30372900)

Sure, they'll have super strength and big muscles. Only to find that their skeletons can't handle the strain, and they end up breaking their arms, legs and ripping tendons with every step.

What's the bet if this thing passes it becomes.. (0)

Anonymous Coward | more than 4 years ago | (#30372994)

What's the bet if this thing passes it becomes standard issue in military forces?

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