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Real-World Synthehol In Development

timothy posted more than 4 years ago | from the volstead-was-an-alien dept.

Sci-Fi 273

Ada_Rules writes "Researchers at the Imperial College London have announced development of an alcohol substitute that has many of the same properties as the Synthehol from the series Star Trek, in that one will get a buzz from it but will not end up with a hangover. In addition you will have the option of getting immediately sober if you so desire it. Let's hope this is not the typical vaporware. It is not that I really want a drink of Synthehol, but with its release I assume Romulan Ale won't be far behind."

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273 comments

First Postohol (-1)

Anonymous Coward | more than 4 years ago | (#30557974)

This is 100 percent non-synthetic.

Re:First Postohol (-1, Troll)

Anonymous Coward | more than 4 years ago | (#30558474)

Also 100 percent stupid. Congrats!

pussy tastes good, feels good, but the Mac users are all faggots who cant appreciate it. sucks to be them! keep using locked down hardware you faggots, cuz its so stylish and hip right? nothin is as hip as a corporation you fucks.

Headache? (0)

Colin Smith (2679) | more than 4 years ago | (#30557978)

What junk are you drinking? Smirnoff?

It isn't the alcohol which gives you a headache. It's the alcohol in combination with the rest of the crap in the beverage.

Either buy decent quality and/or drink a glass of water for each drink and take two paracetamol before you go to bed.
 

Re:Headache? (5, Informative)

White Shade (57215) | more than 4 years ago | (#30558018)

I was always under the impression that taking paracetamol and other similar drugs along with alcohol was rather unhealthy to the liver and whatnot...

Drinking lots of water is always good though!

Re:Headache? (1, Funny)

Colin Smith (2679) | more than 4 years ago | (#30558050)

Drinking lots of water is always good though!

Great. You'd better just stick to the water then.

 

Re:Headache? (2, Interesting)

Forge (2456) | more than 4 years ago | (#30558144)

Never underestimate the value of a tall glass of Dihydrogen Monoxide. What bugs me though is the original stories implication the Romulan Ale dose not yet exist.

On the contrary, I was able to buy Romulan Ale AND Klingon Blood wine at the Star Trek Museum.

Of course this facility also hosts a Bar called "Quark's at which you are encouraged to drink a "Warp core breach", so some of these beverages may not be exactly as advertised.

Re:Headache? (3, Funny)

Anonymous Coward | more than 4 years ago | (#30558524)

"Warp core breach" - A 50/50 shot of vodka and castor oil.

Served at an event with 1,500+ people and about 10 porta potties.

Re:Headache? (1)

peragrin (659227) | more than 4 years ago | (#30558256)

after a night of heavy drinking, a tall glass of dihydrogen monoxide, along with a bottle of gatorade. means I haven't had a hangover in years. That means I can drink a whole bottle of rum, and then shots of tequila, and wake up happier than most people.

Re:Headache? (4, Informative)

wizardforce (1005805) | more than 4 years ago | (#30558062)

You are correct. Paracetamol which is better known as Tylenol, metabolises into N-acetyl-p-benzoquinoneimine which is what actually damages the Liver. [wikipedia.org]

Re:Headache? (4, Informative)

Colin Smith (2679) | more than 4 years ago | (#30558556)

Paracetamol which is better known as Tylenol

Paracetamol is not better known as Tylenol, only a tiny proportion of the world population know paracetamol as Tylenol.

And the GP is not correct.

along with alcohol was rather unhealthy to the liver

Paracetamol is metabolized whether there is alcohol involved or not; Paracetamol is unhealthy for the liver regardless.

   

Re:Headache? (0)

Anonymous Coward | more than 4 years ago | (#30558638)

This isn't the world, it's slashdot.

Re:Headache? (1, Insightful)

wizardforce (1005805) | more than 4 years ago | (#30558750)

Paracetamol is not better known as Tylenol, only a tiny proportion of the world population know paracetamol as Tylenol.

Nonsense. Slashdot is a US centric site and here the brand name is Tylenol.

Paracetamol is metabolized whether there is alcohol involved or not; Paracetamol is unhealthy for the liver regardless.

both of them are bad for the liver. The combination of the two is worse than either of them by themselves. The maximum dose of Tylenol is cut in half if it is taken with a reasonable amount of Alcohol. SO the statement that taking Tylenol and Alcohol together is bad for your Liver is still true.

Re:Headache? (0)

Anonymous Coward | more than 4 years ago | (#30558402)

Drinking lots of water is always good though!

But drinking too much water is also deadly.

Re:Headache? (1)

JWeinraub (773433) | more than 4 years ago | (#30558682)

yes drinking water after each drink is good, i also might add drinking a litre before bed to be a good option as well. and if your stomach can tolerate it, taking two ASA tablets wouldn't be a bad idea either.

Re:Headache? (1)

Hurricane78 (562437) | more than 4 years ago | (#30558722)

No, I found the perfect solution. Tested an proven many, manyy times by me and friends of mine:

Eat a really nice filet steak *before* going out! Or something similar. The redder, the better! (Less destroyed molecules.)

I never have hangovers anymore. I can’t remember the last time I had one. Even if I drink like a hole.

Re:Headache? (3, Informative)

maxume (22995) | more than 4 years ago | (#30558026)

Mixing acetaminophen with alcohol is terrible advice.

Re:Headache? (0)

Anonymous Coward | more than 4 years ago | (#30558030)

It is also the metabolites of ethyl alcohol (such as methyl "wood" alcohol) which cause the hangover.

Re:Headache? (2, Insightful)

HornWumpus (783565) | more than 4 years ago | (#30558112)

Ethanol does not metabolize into methanol.

Further Smirnoff is perfectly fine Vodka.

Anybody who spends more then about $US12 on a 750 of Vodka is just a moron who watches too much TV and believes what he sees on commercials.

Save your money for booze where quality is harder to achieve. Vodka is just pure Ethanol and water.

Some of the most toxic components of booze are leached out of the char in the barrels. If you must get drunk do it on clear booze for lesser hangovers.

Re:Headache? (1)

Colin Smith (2679) | more than 4 years ago | (#30558212)

Further Smirnoff is perfectly fine Vodka.

Smirnoff is paint remover. Try Samson instead. It's not in fact very expensive.

Vodka is just pure Ethanol and water.

Clearly you know your vodkas.

 

Re:Headache? (1)

HornWumpus (783565) | more than 4 years ago | (#30558246)

Try Hertikamp (sp?) it's ten bucks/750ml and recommended by Russians.

I generally find that people who 'know their vodkas' are idiots who think that advertising and spending a lot makes a product better.

I bet you can't tell Smirnoff from your favorite vodka double blind.

Re:Headache? (2, Informative)

zippthorne (748122) | more than 4 years ago | (#30558724)

All American vodkas are equivalently tasteless due to stringent industry regulations on filtering for products bearing the label of vodka. American vodkas are, in fact, pretty much pure ethanol and water.

Re:Headache? (0)

Anonymous Coward | more than 4 years ago | (#30558332)

I live in Ontario - if you can get 750 of Vodka for less than $12 US, you're making it in your bathtub. I think $24-$30 is about typical on the low end.

Re:Headache? (1, Funny)

Anonymous Coward | more than 4 years ago | (#30558064)

This is the stupidest post I've ever read on /. That's saying something.

Re:Headache? (4, Informative)

Abcd1234 (188840) | more than 4 years ago | (#30558142)

Uh, no. Put down the drink, it seems to have damaged your brain.

The primary cause of most hangover symptoms is very simple: Dehydration. The rest are caused by the presence of metabolic by-products of alcohol, which cause, among other things, a decline in available glucose for use by the brain, inhibition of liver function, and vitamin B12 deficiency.

For more information, wikipedia is your friend [wikipedia.org].

And yet, whisky causes worse hangovers than vodka (-1, Flamebait)

Colin Smith (2679) | more than 4 years ago | (#30558480)

For example, since I was taking the piss out of Smirnoff.

http://news.bbc.co.uk/2/hi/health/8416431.stm [bbc.co.uk]

Uh, no. Put down the drink, it seems to have damaged your brain.

Clearly Wikipedia is the font of all knowledge (that was sarcasm (for the Americans)). You haven't had your brain replaced by a parrot brain have you?

Crap red (in particular) wines have a similar effect. You can drink equal amounts of alcohol from poor and good quality reds and the poor quality ones will give you a blinding headache the following day.
 

Re:And yet, whisky causes worse hangovers than vod (3, Informative)

Abcd1234 (188840) | more than 4 years ago | (#30558528)

Clearly Wikipedia is the font of all knowledge (that was sarcasm (for the Americans)). You haven't had your brain replaced by a parrot brain have you?

Huh, clearly you're not illiterate, yet you apparently didn't even read the article I posted, which explicitly mentioned cogeners as exacerbating hangover symptoms.

Meanwhile, nowhere in the article you linked to do I see text which suggests that "It isn't the alcohol which gives you a headache"... probably because that's completely false.

Re:And yet, whisky causes worse hangovers than vod (-1, Flamebait)

Colin Smith (2679) | more than 4 years ago | (#30558634)

Meanwhile, nowhere in the article you linked to do I see text which suggests that

You obviously suffer from premature ej^H^Hreply syndrome. Try reading (and comprehending) the following sentences before your knees jerk so hard you end up with a mouthful of foot.
 

Re:And yet, whisky causes worse hangovers than vod (1)

Abcd1234 (188840) | more than 4 years ago | (#30558704)

I'm sorry, where did I misread? Your initial post flat out state that alcohol plays no role in hangovers. Your subsequent post was to cite an article which does nothing to support that claim, instead identifying an additional factor (cogeners) which plays a role in the product of hangovers. And your last post was entirely content-free.

So, please, enlighten me. What did I miss?

Re:And yet, whisky causes worse hangovers than vod (1)

Abcd1234 (188840) | more than 4 years ago | (#30558738)

Ah, yes, I see, you seem to believe that the statement:

"It isn't the alcohol which gives you a headache. It's the alcohol in combination with the rest of the crap in the beverage."

Is more accurate than simply:

"It isn't the alcohol which gives you a headache."

Of course, it's not. Both are false, and for the exact same reason: They both imply that alcohol, alone, doesn't play a causative role in the production of hangovers, which is silly, given that it's the dehydration caused by alcohol which creates headaches, and the metabolites of alcohol which create many of the other symptoms.

Re:And yet, whisky causes worse hangovers than vod (1)

Hurricane78 (562437) | more than 4 years ago | (#30558754)

That’s simple to explain: Good alcohol has little fusel alcohols. Which are a product of incomplete transformation to alcohol. Or of adding sugar to it. And whiskey simply has more of them, as the strongly distilled vodka.

The sugar (and cheap alcoholic products) inside is why cocktails can be even worse.

Re:Headache? (3, Informative)

adamchou (993073) | more than 4 years ago | (#30558552)

and yet the article in wikipedia clearly says...

"Hypoglycemia, dehydration, acetaldehyde intoxication, and vitamin B12 deficiency are all theorized causes of hangover symptoms".

so how can you authoritatively assert what causes a hangover when the scientists, at least according to that article, aren't even sure?

Re:Headache? (2, Insightful)

Abcd1234 (188840) | more than 4 years ago | (#30558574)

So I suppose, then, that you have a citation or two that demonstrates that alcohol plays on role, whatsoever, in the development of a hangover? I know I've never come across such a thing, which seems to suggest such a theory is *highly* unlikely, but hey, I could certainly be wrong.

Re:Headache? (1)

adamchou (993073) | more than 4 years ago | (#30558614)

i don't need to provide a citation to anything. you're the one that cited wikipedia and misrepresented what it said.

Re:Headache? (3, Interesting)

7-Vodka (195504) | more than 4 years ago | (#30558462)

Actually, other major components of your hangover include:

  1. dehydration
  2. Capillaries in your skull that dilate and expand and put your brain under pressure due to..
  3. acetaldehyde, a metabolite of ethanol
  4. Loss of vitamins and other important materials which get excreted
  5. Liver stress and alcohol poisoning itself

For most of these it doesn't matter what quality vodka you drink.

Re:Headache? (4, Interesting)

causality (777677) | more than 4 years ago | (#30558520)

What junk are you drinking? Smirnoff?

It isn't the alcohol which gives you a headache. It's the alcohol in combination with the rest of the crap in the beverage.

Either buy decent quality and/or drink a glass of water for each drink and take two paracetamol before you go to bed.

There seems to be reason to believe that the hangover is caued by acetaldehyde [wikipedia.org]. Though, I have noticed that some drinks are worse than others. For example, I think red wine has very small amounts of alcohols other than ethanol, alcohols which are a bit more toxic. It's probably also why I seem to get much more subjectively drunk from red wine than an equivalent amount of most liquors. Beer has a similar effect with me, and I assume that's because of the hops. Hops alone are sedating, and in fact hops tea (non-fermented, non-alcoholic) can be used as a natural sleep aid or a way to relax.

From that Wiki article:

Most people of East Asian descent have a mutation in their alcohol dehydrogenase gene that makes this enzyme unusually effective at converting ethanol to acetaldehyde, and about half of such people also have a form of acetaldehyde dehydrogenase that is less effective at converting acetaldehyde to acetic acid.[16] This combination causes them to suffer from alcohol flush reaction, in which acetaldehyde accumulates after drinking, leading to immediate and severe hangover symptoms. These people are therefore less likely to become alcoholics.[17][18]

The drug disulfiram (Antabuse) prevents the oxidation of acetaldehyde to acetic acid, and it has the same unpleasant effect on drinkers. Antabuse is used as a deterrent for alcoholics who wish to stay sober.

Instant (5, Interesting)

Entropy98 (1340659) | more than 4 years ago | (#30558004)

you will have the option of getting immediately sober if you so desire it
 
Can I get drunk again later that night?

Synthetic scotch, synthetic commanders (1)

fotbr (855184) | more than 4 years ago | (#30558016)

We're (apparently) close to the first, time to start making some serious progress towards the second.

Missing the point... (5, Interesting)

tyroneking (258793) | more than 4 years ago | (#30558060)

Having the option of getting immediately sober is rather missing the point of drinking alcohol ... it is the assured descent into a carefree state with no possibility of reversal that is one of the last few pleasures left in life.
Throwing the car keys onto the dining table, pulling a bottle of vodka from the freezer and taking a few shots ... the perfect end to a usually cold, wet and crappy day in the so-called western-civilisation.

Re:Missing the point... (0, Troll)

negRo_slim (636783) | more than 4 years ago | (#30558076)

Having the option of getting immediately sober is rather missing the point of drinking alcohol ... it is the assured descent into a carefree state with no possibility of reversal that is one of the last few pleasures left in life. Throwing the car keys onto the dining table, pulling a bottle of vodka from the freezer and taking a few shots ... the perfect end to a usually cold, wet and crappy day in the so-called western-civilisation.

Spoken like a true alcoholic!

Re:Missing the point... (2, Interesting)

Nethead (1563) | more than 4 years ago | (#30558110)

No, he said a few shots, not the whole bottle. If you have the bottle already in the cooler, and not had just bought it, then you're not quite an alkie yet.

Re:Missing the point... (1)

wizardforce (1005805) | more than 4 years ago | (#30558108)

If you don't want to be sober until later then you shouldn't take the antidote. Alcohol doesn't give you a choice in the matter, synthehol just might.

Re:Missing the point... (1)

tyroneking (258793) | more than 4 years ago | (#30558216)

Seriously man - haven't you ever had a wife/girlfriend/etc. moan at you for being a bit drunk? Now, you can shrug your shoulders and smile sweetly at the Fait Accompli that life has sold her.
In the future she can just slip you a reverse micky (and by which I don't mean some sort of sexual position). Instant disaster.

Re:Missing the point... (4, Interesting)

epine (68316) | more than 4 years ago | (#30558448)

I'm waiting for the first published life reflection on the topic of wife-beater interruptus by a man whose blood-honey got wise to syntheholic Narcan. I'd dearly love to read an explanation by a man who experiences a sudden return to clarity mid swing.

The mind reels at the possibilities. If synaloxone is designed to be easily absorbed through eye membranes (there's another criteria for the designer checklist), it will soon become the feature ingredient in Pepperpoison H. This could lead to the baning of real alcohol. If real alcohol is banned, then only the alcoholics will have it.

Speaking of roids, how many drunks are going to drive home under the influence to maintain the party atmosphere, and quickly jab themselves at the first sign of traffic surveillance or air bag deployment? How is that going to be regulated?

Should this comes to pass, the law of unintended consequence is going to be working double shifts for several decade.

Re:Missing the point... (5, Interesting)

girlintraining (1395911) | more than 4 years ago | (#30558126)

Throwing the car keys onto the dining table, pulling a bottle of vodka from the freezer and taking a few shots ... the perfect end to a usually cold, wet and crappy day in the so-called western-civilisation.

"I asked many people why they drank so much but never received an explanation that I fully understood. It was the tales of their escapades while under the influence of drink that brought me nearest to comprehending their need for it. It seemed to give them a few hours of freedom from rules which, during the rest of their lives, they reluctantly obeyed. If this was true, then in the example of my life lay a cure for drunkenness... never to conform at all." ~ Quentin Crisp, The Naked Civil Servant

Re:Missing the point... (2, Insightful)

tyroneking (258793) | more than 4 years ago | (#30558228)

... but we're not all writers or rock stars.

Re:Missing the point... (1)

hitmark (640295) | more than 4 years ago | (#30558338)

maybe not, but with the workforce surplus that this planet is experiencing, "cheap" entertainment is a must have unless the elite wants a big rebellion on their hands...

Antidote (5, Funny)

proficiovera (1099145) | more than 4 years ago | (#30558086)

So if some drunk is being obnoxious at the bar you can now slip the antidote in his drink?

slip the antidote in his drink? (1, Insightful)

Anonymous Coward | more than 4 years ago | (#30558496)

The antidote for being drunk or the antidote for being obnoxious?

Re:Antidote (1)

Renraku (518261) | more than 4 years ago | (#30558544)

That wouldn't be a bad idea actually.

"Calm the hell down, get the hell out, or take this antidote."

The drunk would have three choices. To stop being loud and obnoxious, to leave the establishment, or to take the antidote. Knowing most drunks, he'd take a swing at someone, but then it crosses into the legal territory and is no longer a civil matter. Then there would be even fewer excuses for synthehol-related crimes. Drunk driving? Stupid, you get a year in jail for not taking the antidote. Drinking and dialing? Stupid, don't call me ever again. Drinking and deriving? Stupid, get out of my math class.

Not really (2, Interesting)

Anonymous Coward | more than 4 years ago | (#30558096)

Prof Nutt and his team are concentrating their efforts on benzodiazepines, of which diazepam, the chief ingredient of Valium is one. Thousands of candidate benzos are already known to science. He said it is just a matter of identifying the closest match.

From my benzo experience, I doubt any benzo will replace alcohol. Alcohol effects a whole range of neurotransmitters, not just GABA.

And this is the "we can just turn it off" part:

“I’ve been in experiments where I’ve taken benzos,” said Professor Nutt. “One minute I was sedated and nearly asleep, five minutes later I was giving a lecture.

Since good old valium, benzos have been getting shorter and shorter acting with faster and faster clearances, but you can get such short actions that to get any sort off effect you have to shovel the stuff in IV just to keep up with the clearance. I don't know of any oral approach than can be turned off like a switch.

And doesn't someone already have an "off-switch" type pill for good old ethanol. It doesn't turn off the liver processing or clear the acetylaldehyde souring your stomach, but it would clear your head enough to drive.

Re:Not really (4, Insightful)

Anonymous Coward | more than 4 years ago | (#30558304)

And this is the "we can just turn it off" part:

“I’ve been in experiments where I’ve taken benzos,” said Professor Nutt. “One minute I was sedated and nearly asleep, five minutes later I was giving a lecture.

I think we've seen this show before. It was called the 1950's and 60's.

Can't sleep? Take a pill to sleep. Trouble waking up? Take a pill to wake up. Now you're really awake and agitated and jittery? Take a pill to calm you down.

Be sure to wash those pills down with a nice distilled beverage of your choice and don't forget have a refreshing smoke.

Head researcher (-1, Troll)

schmidt349 (690948) | more than 4 years ago | (#30558114)

It seems that the head researcher on this project is David Nutt, who was sacked by the British government over his "controversial" views on drugs like THC and ecstasy. What a bunch of blowhards; but then I'm not one to talk, since the teabaggers here hold the same rigid views.

Re:Head researcher (5, Interesting)

Doug Neal (195160) | more than 4 years ago | (#30558416)

It seems that the head researcher on this project is David Nutt, who was sacked by the British government over his "controversial" views on drugs like THC and ecstasy. What a bunch of blowhards; but then I'm not one to talk, since the teabaggers here hold the same rigid views.

The guy is awesome. Having been sacked in a purely political manoeuvre by Jacqui Smith (spit) it sounds like he now leads an Alexander Shulgin-like life of synthesising new chemicals and trying them out faster than the government can ban or control them. Sadly the same reasons for him being sacked will probably mean that this project doesn't gain any traction. Politics trump science and reason...

No thanks, I'm drinking. (5, Interesting)

Tackhead (54550) | more than 4 years ago | (#30558132)

Let's read between the lines here...

From TFA:

Professor Nutt believes that the new drug, which would need licensing, could have a dramatic effect on society and improve the nation's health

In this one sentence we see: (a), an appeal to the neo-prohibitionist/nanny-stater lobby to spin this story into a positive, and (b), because you can't make this stuff at home, a pharmaceutical company is going to get a cut. Alcohol's easy to make - take some yeast and just about any form of sugar (or starch that can be converted via enzymatic action into sugar) - and you've got yourself the foundations of beer, wine, and distilled spirits. Synthetic valium, not so much.

Net effect here is that we all wind up hooked on benzos as depressants, rather than alcohol. Hey, that's fine if valium's his depressant of choice, but it's not one of mine. What's next, a move to replace the caffeine in coffee (my stimulant of choice :) with slightly-modified speed?

From the TFsummary:

It is not that I really want a drink of Synthehol, but with its release I assume Romulan Ale won't be far behind.

As cool as it sounds, that's not a feature, that's a bug.

Allow me to nerd out for a bit: When Synthehol [memory-alpha.org] was invented, Romulan Ale [memory-alpha.org] (which presumably contained real alcohol) became illegal.

And if you go back and re-read TFA, you'll see that's pretty much where this is goin. This guy's not interested in an alternative to alcohol, he's looking for a substitute for alcohol. Even if he is working in good faith, his efforts will be used to help the neo-prohibitionists. And I can't get down with that. Because I like real ale, Romulan or not. (Homebrewing is like turning half the basement into a mad scientist's chemistry lab for a day, and it's all the more fun because you get to consume the product of your experiment when it's done!)

Around this time of year, I usually say "A drink? No thanks, I'm driving." But on this one, I'm gonna have to say "Benzos? No thanks, I'm drinking."

Re:No thanks, I'm drinking. (2, Insightful)

hitmark (640295) | more than 4 years ago | (#30558310)

meh, just wait for the recipe to hit the net, and for someone to come up with a way to make it in a bathtub...

Re:No thanks, I'm drinking. (5, Interesting)

King_TJ (85913) | more than 4 years ago | (#30558440)

You make a valid point about the potential killing off of the art of home-brewing ... but other than that (very valid) issue, I'm not so sure your other complaints would really matter in the long-run. At the end of the day, the drugs society considers "more acceptable to consume regularly" are really just a matter of how popularized they've become. Caffeine, for example, is pretty much treated like a major food group, since it's found in everything from soda to cappuccino. Heck, they've even got caffeinated water you can buy. But if some other drug (like a small dose of the contents of ADD/ADHD medications, perhaps?) was the drug of choice to insert into carbonated beverages and such, instead? It might have been caffeine people generally thought was a little "unsettling" or "weird" to ingest as part of recreational drinking.

Missing the point (2, Funny)

nielsenj (313987) | more than 4 years ago | (#30558138)

Who cares about getting sober instantly ? I'd rather get instantly wasted. I'll take a Pan Galactic Gargle Blaster over romulan ale any day!

Oops (0)

Anonymous Coward | more than 4 years ago | (#30558190)

"I've been in experiments where I've taken benzos," said Professor Nutt. "One minute I was sedated and nearly asleep, five minutes later I was giving a lecture."

But the students couldn't figure out why he insisted on being called Mr. Hyde. Or why he kept throwing chairs.

Romulan Ale? (0)

Anonymous Coward | more than 4 years ago | (#30558198)

But Bones, you know that stuff's illegal!

Better Profit Through Pharmaceuticals (4, Insightful)

handy_vandal (606174) | more than 4 years ago | (#30558230)

"Prof Nutt and his team are concentrating their efforts on benzodiazepines, of which diazepam, the chief ingredient of Valium is one."

In other words, let's invent another Happy Pill that will make big profit for Big Pharmco. And we'll call it an "alcohol substitute" because alcohol is well-known as the active ingredient in alcoholism, and you're in favor of a cure for alcoholism, right?

Good thing they're not calling it a "Valium analog", what with Valium's well-known and deserved reputation for causing addiction, tolerance, and withdrawal [wikipedia.org].

Re:Better Profit Through Pharmaceuticals (1)

couchslug (175151) | more than 4 years ago | (#30558374)

A "happy pill" is a reasonable goal, as is chemical pleasure (well, all pleasure is chemical) in general.

Information wants to be free, and information that valuable will be free in short order after the product is invented.

Re:Better Profit Through Pharmaceuticals (2, Interesting)

Hurricane78 (562437) | more than 4 years ago | (#30558772)

Benzoes? How did a friend say: I tried everything. Even Heroine. But that benzo shit? That’s even worse!

Romulan Ale (1)

feldhaus (813019) | more than 4 years ago | (#30558232)

Romulan Ale [memory-alpha.org] is alcoholic, not sythoholic and a cocktail recipes are available at that link to those with no sense of self-preservation.

Toxicity (4, Insightful)

hwyhobo (1420503) | more than 4 years ago | (#30558244)

If it is ingested orally, then it will be metabolized in the liver. What about its toxicity? If it's the same or higher than alcohol, then the illusion of safety may in the end be detrimental to the health of the user.

Re:Toxicity (0)

Anonymous Coward | more than 4 years ago | (#30558696)

IMO, there should be no illusion of safety to begin with. Why? Because, in a statistical overview kind of way, people are stupid, and they'll do the same stupid things with a new chemical that they do with the old ones - all these things that aren't supposed to be taken with anything else end up being taken with every imaginable combo of other things anyway. We'll be seeing the same celebrity autopsies where this stuff is in their bloodstream along with cocaine and alcohol and the relaxant/antidepressant of the day :|

Alcohol didn't exist more than 3,000 years ago? (1)

RNLockwood (224353) | more than 4 years ago | (#30558296)

The article says that alcohol has only been around for 3,000 years. This implies that leavened bread has only been around for that long. Wonder what the yeasts were producing before and why so many animals have the enzyme alcohol dehydroginase.

Please tag such stories "Telegraph (UK)." (0)

Anonymous Coward | more than 4 years ago | (#30558298)

This would make it clear that the degree of correlation between scientific assertion and journalistic conclusion in the article might not be actually be high enough to support any conclusion of statistical significance, let alone causality.

The Puritans won't like this. (4, Insightful)

plopez (54068) | more than 4 years ago | (#30558322)

Or the Catholics. If you're going to have fun, the punishment must be built-in.

Don't lump us Catholics in with the Puritans. (0)

Anonymous Coward | more than 4 years ago | (#30558796)

Three words: Wedding at Cana.

The real questions (1)

mmmmbeer (107215) | more than 4 years ago | (#30558326)

Can I blame my mistakes on my friends and a case of synthehol? Can I drink a girl pretty with synthehol? Will this help ugly people get laid? These are the important questions!

From the article... (0)

Anonymous Coward | more than 4 years ago | (#30558384)

Professor Nutt got sacked.

I'm not alone (5, Insightful)

7-Vodka (195504) | more than 4 years ago | (#30558408)

You know the first thing I'm gonna fucking do, is mix this shit in my rum and cokes while chewing some nicotine gum and smoking a fat joint.
And I know I'm not the only one.

Vaporware?? (1)

davidwr (791652) | more than 4 years ago | (#30558438)

It better be vaporware.

I love the aroma of a good glass of real wine. If the synthetic stuff doesn't measure up then what's the point?

Containers (0)

Anonymous Coward | more than 4 years ago | (#30558446)

Don't forget to sell it in Transparent Aluminum cans.

GHB/GBL (0)

Anonymous Coward | more than 4 years ago | (#30558468)

I have always found GHB and/or GBL to be excellent alcohol substitutes. They wear off in a few hours and leave you with no hangover. Unless you mix it with other depressants (alcohol, I'm looking at YOU!) or otherwise overdose you are fine the next day. Not sure about the sobering up-pill though, I don't know enough about the selectivity of their action on GABA. My guess is that it's similar to bensodiazepines.

Like this will be accepted. (1)

TheRealGrogan (1660825) | more than 4 years ago | (#30558498)

Yeah, right. Like society is going to suddenly get over their prejudices about "drugs" and it's going to be acceptable to consume this, take an antidote and drive or go to work or other drinking taboo. In societies where they still criminally prosecute and jail people for the mere possession of marijuana. (which to an established, regular user is relatively harmless)

Actually, we do have safe alcohol substitute (5, Informative)

lawpoop (604919) | more than 4 years ago | (#30558536)

We already have alcohol substitutes ( read: recreational drugs ) that are safer than alcohol. Only problem is, they're illegal.

You can't handle the truth [boston.com]. Dr. David Nutt, the British government scientist that was recently fired, did an exhaustive study of the real impact of recreational drugs. Herion was 8.32, alcohol 5.54, Cannabis 4.00, LSD 3.68 and Ecstacy 3.27. A higher score is worse.( Many other drugs were in the study).

So we already have several safer alternatives to alcohol.

I am not a doctor (1)

vorlich (972710) | more than 4 years ago | (#30558652)

but I know someone who is. They would advise all slashdotters (and anyone else for that matter) that it is an incredibly bad idea to take any paracetamol when you have been drinking alcohol http://en.wikipedia.org/wiki/Paracetamol [wikipedia.org].
It is very toxic to your liver. Better to drink responsibly, consume quality products and remember that a reasonable consumption of water only protects you from the effects of hydration but has no real effect on the contaminants that cause the headache and nausea. Wait until the alcohol has been metabolised (2 hours per unit) and then take the lowest dose possible or some other analgesic.

The only problem is... (1)

Hurricane78 (562437) | more than 4 years ago | (#30558668)

...that in the real world, alcohol making you drunk is the whole point! We certainly don’t drink it because of the bitter, burning taste. ^^

If this had any chance of being a success, then people would already prefer non-alcoholic cocktails and brews for a looong time.
And I don’t see that being the case, or ever happening.

Re:The only problem is... (1)

Hurricane78 (562437) | more than 4 years ago | (#30558698)

Aaah, shit. I forgot to read TFS.

Now where is the delete button for my comment??
Or: What is the ^H equivalent for whole comments?

Do Not Mix With Alcohol? (1)

Plekto (1018050) | more than 4 years ago | (#30558680)

If you read the article, they are using substances that are related to the same family or compounds that you find in Valium and other depressants. You very well might see them succeed, but I can't imagine drinking beer that has a warning label to not mix with (real)alcohol.

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