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Old Stems Cells Young Again — Via Vampirism

ScuttleMonkey posted more than 4 years ago | from the ecstatic-twilight-fans dept.

Medicine 109

pdragon04 writes to tell us that in recent tests a Howard Hughes Medical Institute team has found that through exposure to "young" blood cells, bone marrow stem cells start to act young again as well. "The researchers have not yet isolated the blood-borne factors that can switch old stem cells back to a more youthful state, but their results are consistent with other recent studies that show stem-cell aging may be reversible. Together those results suggest that it might one day be possible to boost the practical lifespan of stem cells, and thereby increase the body’s resistance to disease and age-related degeneration."

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But can you walk out in sunlight afterwards? (4, Funny)

gestalt_n_pepper (991155) | more than 4 years ago | (#30953406)

And do you respect yourself in the morning, um, er evening? Whenever....

Re:But can you walk out in sunlight afterwards? (1)

Jhon (241832) | more than 4 years ago | (#30953530)

You can. Providing you immediately jump in water.

Warning: This will reverse the effects and kill anyone else who tries to use your blood.

Re:But can you walk out in sunlight afterwards? (5, Informative)

mfh (56) | more than 4 years ago | (#30953926)

Depends on which vampire you are:
http://imgur.com/DwTbo.jpg [imgur.com]

Re:But can you walk out in sunlight afterwards? (0)

Anonymous Coward | more than 4 years ago | (#30954054)

They screwed up the Lestat part of the chart, I think. He should have a half-drop for sun sensitivity and quick healing, instead of a full drop for the first and nothing for the second.

Re:But can you walk out in sunlight afterwards? (1)

locallyunscene (1000523) | more than 4 years ago | (#30955464)

+1 for having Bunnicula

-3 for missing I Am Legend.

Re:But can you walk out in sunlight afterwards? (1)

tsm_sf (545316) | more than 4 years ago | (#30959074)

Those were zombies or something else freaky.

Agree on Bunnicula though. "Pounding a steak" still cracks me up.

Re:But can you walk out in sunlight afterwards? (0)

Anonymous Coward | more than 4 years ago | (#30954114)

Easy there Daybreakers!

Let me get this straight... (4, Funny)

Monkeedude1212 (1560403) | more than 4 years ago | (#30953428)

I'll live forever if I eat babies?

Re:Let me get this straight... (2, Funny)

Jabrwock (985861) | more than 4 years ago | (#30953452)

My god, South Park/Christopher Reeves was right!

Re:Let me get this straight... (1)

gestalt_n_pepper (991155) | more than 4 years ago | (#30953634)

This surprises you?

Re:Let me get this straight... (1)

Sponge Bath (413667) | more than 4 years ago | (#30953816)

It might have been a reference to Battlestar Galactica. Remember when President Roslin was getting injected with cyclon fetus juice? It's just one more step to munchin' down. nom, nom, nom...

Re:Let me get this straight... (0)

Anonymous Coward | more than 4 years ago | (#30953460)

and maybe you'll sparkle too!

Re:Let me get this straight... (3, Funny)

KarrdeSW (996917) | more than 4 years ago | (#30953470)

I'll live forever if I eat babies?

Are you sure you want to be that young? I'll stick to eating 18-year-old blond women.

If this line of reasoning continues it's only going to get creepier.

Re:Let me get this straight... (2, Funny)

macraig (621737) | more than 4 years ago | (#30953858)

You mean like:

So Jeffrey Dahmer was really in the forefront of anti-aging research, then?

Re:Let me get this straight... (1)

PopeRatzo (965947) | more than 4 years ago | (#30954058)

I'll stick to eating 18-year-old blond women.

Whatever works for you, but most of us prefer live women. How do you get the taste of formaldehyde out of your mouth?

And does your employer at the funeral home know what you're up to?

Re:Let me get this straight... (2, Interesting)

WillDraven (760005) | more than 4 years ago | (#30953488)

Well, going just by the summary, the marrow has to be exposed to the young blood cells. Now I doubt they would survive the digestion process very well, so you probably have to drain their blood and IV it like a heroin junkie while it's still fresh. Or even worse drill or punch a hole in your bone to shoot it directly into the marrow.

Re:Let me get this straight... (0)

Anonymous Coward | more than 4 years ago | (#30959790)

I'm still waiting to see a DIY on hackaday.

Re:Let me get this straight... (4, Informative)

starbugs (1670420) | more than 4 years ago | (#30953602)

Silly, It's 'EXPOSURE' (not 'PHAGOCYTOSIS') to Young blood cells.

Think Hugh Hefner, not Silence of the Lambs.

Re:Let me get this straight... (2, Funny)

operagost (62405) | more than 4 years ago | (#30953728)

Damn. *puts the fava beans and chianti away*

Re:Let me get this straight... (2, Funny)

2obvious4u (871996) | more than 4 years ago | (#30954556)

Gee, I was thinking Michael Jackson....


to soon?

Re:Let me get this straight... (4, Interesting)

fyoder (857358) | more than 4 years ago | (#30953604)

I'll live forever if I eat babies?

It's a little more complicated than that. From the article:

To see if younger blood could reverse the sluggishness of aging blood cells, the researchers began by surgically joining the bloodstreams of pairs of mice that were of different ages, but nearly clones of one another.

So not eat, but perhaps get transfusions from a much younger sibling. It would probably have to be the same blood type. Simply sucking the blood of random babies is unlikely to be effective and won't be appreciated by their parents or society, so probably best not to.

Re:Let me get this straight... (1)

Gilmoure (18428) | more than 4 years ago | (#30954918)

Time to keep young clones around? At what age do you have to get rid of them and start a new one? Ages 13-17, I was pretty unpleasant to be around.

Re:Let me get this straight... (2, Insightful)

ColdWetDog (752185) | more than 4 years ago | (#30956318)

Ages 13-17, I was pretty unpleasant to be around.

"You" would likely be in a vat, frozen in liquid nitrogen. What's not to like?

Re:Let me get this straight... (1)

ascari (1400977) | more than 4 years ago | (#30956654)

Crap! I'm the youngest sibling. Destined for exploitation evidently.

Re:Let me get this straight... (1)

mdielmann (514750) | more than 4 years ago | (#30959736)

"And to think, all I needed was the blood of a young boy."

Re:Let me get this straight... (5, Funny)

frank_adrian314159 (469671) | more than 4 years ago | (#30953660)

I'll live forever if I eat babies?

That's how Dick Cheney does it.

Re:Let me get this straight... (4, Funny)

Requiem18th (742389) | more than 4 years ago | (#30956024)

He discovered it accidentally back when he was busy funding the Mongol Empire.

Re:Let me get this straight... (1, Funny)

macraig (621737) | more than 4 years ago | (#30953834)

So Jeffrey Dahmer was really in the forefront of anti-aging research, then?

Re:Let me get this straight... (2, Funny)

Arancaytar (966377) | more than 4 years ago | (#30953868)

Don't forget to bathe in the blood of virgins regularly.

Re:Let me get this straight... (4, Funny)

PopeRatzo (965947) | more than 4 years ago | (#30954026)

through exposure to "young" blood cells, bone marrow stem cells start to act young again as well

How do you think Demi Moore managed to keep it together so long?

Re:Let me get this straight... (1)

Lithdren (605362) | more than 4 years ago | (#30954200)

I'll live forever if I eat babies?

Only if you bathe in their blood.

Shades of 'Blindsight' (1)

Krishnoid (984597) | more than 4 years ago | (#30953448)

It almost sounds like Peter Watts' [slashdot.org] concepts are moving from his fiction into mainstream science. Well, I for one ...

There Is Nothing About Vampirism (5, Informative)

Anonymous Coward | more than 4 years ago | (#30953454)

in TFA.

Re:There Is Nothing About Vampirism (1)

corbettw (214229) | more than 4 years ago | (#30954250)

I'll bet this particular Anonymous Coward is a vampire himself, trying to convince us all they don't exist.

I'm onto your schemes, bloodsucker!

Re:There Is Nothing About Vampirism (2, Informative)

BJ_Covert_Action (1499847) | more than 4 years ago | (#30954608)

Lack of substance in a particular article has never stopped some, "creative editing," on slashdot before ;)

Well duh! (1)

KiwiCanuck (1075767) | more than 4 years ago | (#30953458)

Didn't they see the Dark Angel episode where Logan got a blood transfusion from Max, and was the able to walk a couple of eps later. Clearly researcher don't watch enough scifi. ~:-)

Re:Well duh! (1)

kalirion (728907) | more than 4 years ago | (#30953672)

Or Heroes, where a few drops of Claire's blood gives temporary regeneration powers to the receiver. Something Claire apparently forgot about in the most recent episode....

Re:Well duh! (1)

jeffmeden (135043) | more than 4 years ago | (#30953848)

She has forgotten about that in every single episode since it happened! I just explain it away as a special property of her blood that only worked on others after Mohinder processed it. Yeah, that's it.

God I wish I could stop watching that show.

Re:Well duh! (1)

decoy256 (1335427) | more than 4 years ago | (#30953936)

Except Takezo Kensai (A.K.A. Adam Monroe) used just his blood to heal Peter... and supposedly Monroe and Claire had the same ability.

Re:Well duh! (1)

LT Stephen (1693790) | more than 4 years ago | (#30958840)

Actually it was Nathan that he healed. Still not sure how he recovered from being shot.

Paging Dr. Bathory... (4, Interesting)

fuzzyfuzzyfungus (1223518) | more than 4 years ago | (#30953474)

Elizabeth Bathory [wikipedia.org] could have told them all about it.

Let's keep this one to ourselves... (1)

swanzilla (1458281) | more than 4 years ago | (#30953490)

FTA:

To see if younger blood could reverse the sluggishness of aging blood cells, the researchers began by surgically joining the bloodstreams of pairs of mice that were of different ages, but nearly clones of one another.

PETA is going to go ape-shit.

Re:Let's keep this one to ourselves... (1)

Totenglocke (1291680) | more than 4 years ago | (#30953710)

And I'll say what I always say - fuck PETA. Yes, I'm against being unnecessarily cruel to animals, but if you eliminate animal testing then several areas of science will pretty much grind to a halt. I for one would gladly sacrifice countless animals if it means we can slow down the rate of aging.

Re:Let's keep this one to ourselves... (1)

patlabor (56309) | more than 4 years ago | (#30953878)

Watch the documentary 'Earthlings' and then tell me how you feel about this issue.

Re:Let's keep this one to ourselves... (1)

poetmatt (793785) | more than 4 years ago | (#30954408)

we are a product of speciesism, what do you expect us to do, refuse our natural instincts? Remind me of that the next time you try to counterpoint it.

I for one would gladly sacrifice countless amounts of any species if it is done voluntarily and without duress by the sentient/cognizant ones, to benefit humanity and/or the advance of science. Lots of people believe in this kind of concept, even though it is easily subverted. Some call it service (military or otherwise), or employment.

Re:Let's keep this one to ourselves... (0)

Anonymous Coward | more than 4 years ago | (#30953976)

if you eliminate animal testing then several areas of science will pretty much grind to a halt.

That's not an argument, though. You could just as well say we can't give up slavery because if we do, the cotton industry will suffer, or we can't stop the war on drugs because without mandatory minimum sentencing laws for pot smokers, prison labor will suffer.

If you're debating ethics, this simply isn't an argument.

Re:Let's keep this one to ourselves... (3, Insightful)

Totenglocke (1291680) | more than 4 years ago | (#30954110)

Science is necessary for medical treatments meaning saving and improving lives. Animals are not more important than humans and if X animals have to die so that countless human lives can be saved / horrible medical conditions can be treated so that their quality of life is better, then yes, it's a worthwhile trade off.

Your argument would have a point if we were talking about human testing against people's will (as was done during the Holocaust). However, since we're talking about animal testing, the ethics part doesn't fit in.

Re:Let's keep this one to ourselves... (0)

Anonymous Coward | more than 4 years ago | (#30960202)

and humans are no more important than any other animal .. except in over inflated human egos ..

humans are behaving like a virus on the planet .. it and the rest of the other animals undeniable would be better off without us ..

and as for human tests during the holocaust (like there has only ever been one) this has occurred may times in so called modern democracies .. one example being the CIA MK-ULTRA experiments on mental patients etc. .. and in fact is happening every day in american prisons .. with inmates being use as drug test guinea pigs ..

the human animals that think they are more worthy and above the other animals living on this planet are laughable . but they are most certainly not funny . just very dangerous and in the end self destructive because of their self importance ..

just for one minute contemplate the implications of conquering disease and death .. what do yo think would happen on this planet if that were to happen ??? unending war .. starvation .. ecosystem destruction etc.

and who would get to be the beneficiaries of such discoveries but the mostly white ruling class ..

of course the ruling class would be last to go ..

or maybe they think that if they can conquerer death and disease for themselves .. through medical research payed for with public funds .. they can then simply kill off the working (slave) class and keep the planet for themselves .. as the rest of us are eating their food .. drinking their water .. and breathing their air ..

the only upside of practical immortality for the ruling class .. is that the health and sustainability of the environment will become of great importance to those possessing it ..

Re:Let's keep this one to ourselves... (1)

Arthur Grumbine (1086397) | more than 4 years ago | (#30954956)

To see if younger blood could reverse the sluggishness of aging blood cells, the researchers began by surgically joining the bloodstreams of pairs of mice that were of different ages, but nearly clones of one another.

PETA is going to go ape-shit.

Not to mention what Dr. Egon Spengler's [wikipedia.org] reaction will be.

Re:Let's keep this one to ourselves... (1)

interkin3tic (1469267) | more than 4 years ago | (#30956614)

PETA is going to go ape-shit.

True, but off-topic. They're probably going to go ape-shit over someone wearing fake leather. I doubt they are going to be reading the methods sections of scientific papers, they'd probably get upset over the non-cruelty-free ink the paper was printed on first.

Side effects include: (3, Funny)

gad_zuki! (70830) | more than 4 years ago | (#30953492)

Side effects include:

Wearing pasty white makeup
Being especially emo and whiney
Changing username to MrsCullen4Ever3
Wearing black nail polish
and hanging out with shirtless underage guys.

Re:Side effects include: (0)

Anonymous Coward | more than 4 years ago | (#30953892)

cool story bro

Re:Side effects include: (1)

BJ_Covert_Action (1499847) | more than 4 years ago | (#30954644)

and hanging out with shirtless underage guys.

That's a side effect? I thought that was a feature!

/shudder

Re:Side effects include: (-1, Flamebait)

Anonymous Coward | more than 4 years ago | (#30957788)

and hanging out with shirtless underage guys.

That's a side effect? I thought that was a feature!

I'm sure for you it would be. But I haven't figured out whether you're gay or just Jewish.

Sorry, Buffy.... (1)

X'16435934 (988304) | more than 4 years ago | (#30953518)

I'd love to go out with you tonight, but something just came up-
now I have to read this big research paper...

-

Diabetes was mentioned, so... (4, Informative)

Orbijx (1208864) | more than 4 years ago | (#30953520)

I read TFA (gasp! rare!)

They were using older and diabetic mice for their tests.

I can't help but wonder if this discovery may have some effect on diabetes treatments in the future. For diabetics who still have some pancreatic function, and aren't wholly dependent on pills, maybe the results found from this research could help them.

As for those who are dependent on pills, needles, and the like, I could wonder what it would do for them.

The article didn't really clarify what happened with the diabetes in the affected test subjects, though, so I lack that answer.

Re:Diabetes was mentioned, so... (1)

fuzzyfuzzyfungus (1223518) | more than 4 years ago | (#30953616)

Hmm... Do you think that medical ethicists would whine if insulin pumps [wikipedia.org] were replaced with tiny little stunted clone fetuses, permanently grafted into the host's circulatory system? You could even dress them up in adorable little baby clothes!

Re:Diabetes was mentioned, so... (1)

ImprovOmega (744717) | more than 4 years ago | (#30954692)

Hmm... Do you think that medical ethicists would whine if insulin pumps [wikipedia.org] were replaced with tiny little stunted clone fetuses, permanently grafted into the host's circulatory system? You could even dress them up in adorable little baby clothes!

Hmm...given that real fetuses currently can induce gestational diabetes [wikipedia.org] I'm not sure your fetal insulin pump replacement plan is going to work like you hope.

Probably just matters how you write up the grant paper work though.

Re:Diabetes was mentioned, so... (1)

Gilmoure (18428) | more than 4 years ago | (#30954970)

And if they were stuck to your forehead!

Re:Diabetes was mentioned, so... (1)

compro01 (777531) | more than 4 years ago | (#30954628)

For diabetics who still have some pancreatic function, and aren't wholly dependent on pills, maybe the results found from this research could help them.

I think you meant dependent on injections. The pills in question would be to either boost insulin sensitivity (Useful for type 1 (no pancreatic function) and 2 (insufficient pancreatic function)) or boost pancreatic function (only useful for type 2). Injections provide insulin directly (required in type 1, used in type 2 if other options are insufficient or can't be used for other reasons).

Re:Diabetes was mentioned, so... (1)

Orbijx (1208864) | more than 4 years ago | (#30955932)

I'm a type 2 diabetic. I only use pills, diet, and exercise to treat my symptoms, since the insulin I was taking was causing me to bottom out (50-60 mg/dL or lower). I would love something that would drop the need for (up to) 2.5 gigantic pills out of my daily regimen (especially given the side-effects (of which my gut would thank me to avoid) of Metformin).

I did address the needle group in my thoughts above, but a little haphazardly, perhaps. :)

Well (2, Informative)

elsJake (1129889) | more than 4 years ago | (#30956914)

A fairly older friend of mine's got type 2 diabetes and he sais he's been keeping it under control with diet , exercise and a couple of plant extracts.

Now I'm not big on all the "nature treatments" and stuff if i can't read a proper scientific paper on the active ingredients and how they go about their business , and frankly i haven't given it much effort but it seems to work for him and he no longer has to take those nasty sulfamides the docs were feeding him.

So here's a list of the stuff he takes:
1) gymnema sylvestre (he's taking some pills called diabecon containing that , and i'm not sure but i think they're local , but anything containing that should be good)
2) momordica charantia (some kind of cucumbers ., he's taking "insulina verde" (ie green insulin in english) by hofigal , also local i think) You should be able to find tinctures containing that anywhere though.
3) Diabetico , made by Tang xin so ..china town ?. It's supposed to be plant based , haven't the slightest clue what it contains , probably more of what i've listed in a different form.
4) Diavit , made by some local guy , ingredients are: Vaccinium myrtillus , Hippophae rhannoides

So search for those ingredients and see what you can find locally that's got the same basic things, so far it's been working great for'em and his mom as well.


Now if you're serious about your health you're going to permanetly fix this , and not just rely on plants to keep you above the floating line.
I've studied everything i could related to type 2 diabetes , and what has to be done about it. You know what i've noticed ? Body builders do everything a type 2 diabetic is supposed to do to maintain healthy , because they need insulin sensitivity (what you're lacking) in order to reach their goals.
As such i recommend you start bodybuilding :). One great site i found ( abcbodybuilding.com ) has great articles on diet and exercise , and you'll probably be glad you're getting in shape as well.
You've probably heard it all before , but health is worth the effort , do something about it before it's too late. My friend is too lazy to do it , even though i've shown him the results (I'm sorta predisposed to diabetes myself , i just started weightlifting and dieting like the Terminator in time and my bloodwork went from red to black in a few months). The deal is , you have to keep at it , it's a lifestyle change , not a quick fix.


Good health to you mate.

Re:Diabetes was mentioned, so... (1)

Wiarumas (919682) | more than 4 years ago | (#30954910)

So, it is uncertain if our future overlords will be immortal diabetics.

Meh (2, Funny)

Anonymous Coward | more than 4 years ago | (#30953524)

I'll stay young the old-fashioned way: eat sensibly, exercise, and suck the life force from teenage virgins.

Re:Meh (3, Funny)

smellsofbikes (890263) | more than 4 years ago | (#30955232)

I'll stay young the old-fashioned way: eat sensibly, exercise, and suck the life force from teenage virgins.

no offense but I'm going to try exactly the opposite: eat outrageously, slack, and get teenage virgins to suck the life force out of me.

They Always Say... (1)

Nom du Keyboard (633989) | more than 4 years ago | (#30953526)

They always say that Science is catching up to Science Fiction.

Now it appears that Science is catching up to Paranormal as well.

Re:They Always Say... (1)

H0p313ss (811249) | more than 4 years ago | (#30953670)

They always say that Science is catching up to Science Fiction. Now it appears that Science is catching up to Paranormal as well.

Actually my thought was this sounds a lot like the treatments talked about in Heinlein's [wikipedia.org] Methuselah's Children [wikipedia.org]

Just another piece of evidence (1)

zippthorne (748122) | more than 4 years ago | (#30958930)

Supporting a hypothesis of "Quantum Immortality" an obvious alternative to the simulation hypothesis [wikipedia.org] , with references to the anthropic principle.

If every possible universe exists in quantum superposition, then I am experiencing this one because it is the one in which I live the longest, or the one in which I never cease to exist.

O Lord. What will Fox news say... (0, Troll)

valadaar (1667093) | more than 4 years ago | (#30953540)

Ye gods this is going to be interesting...

Re:O Lord. What will Fox news say... (1)

gestalt_n_pepper (991155) | more than 4 years ago | (#30953698)

They'll wire out over it, of course. Anything to keep "The Base" stirred up in their trailers.

Simpsons did it! (1)

jameskojiro (705701) | more than 4 years ago | (#30953570)

Mr. Burns is well known to have lived beyond his years due to infusions of blood from young boys.

Looking forward to Eternal Youth (2, Insightful)

physburn (1095481) | more than 4 years ago | (#30953576)

Except acting young again, does mean they stem cells will have lost any genetic damage, that occurred though aging. Perphaps some day though medicine will be able to produce truely young stem cells, but that would require checking that the DNA hasn't mutated from the orignal young cell line.

---

Stell Cells [feeddistiller.com] Feed @ Feed Distiller [feeddistiller.com]

Re:Looking forward to Eternal Youth (1)

interkin3tic (1469267) | more than 4 years ago | (#30956828)

Except acting young again, does mean they stem cells will have lost any genetic damage, that occurred though aging. Perphaps some day though medicine will be able to produce truely young stem cells, but that would require checking that the DNA hasn't mutated from the orignal young cell line

The current thinking in the field is that stem cells are generally more resistant to DNA damage than many other types of cells. A lot of damage comes from when the cell replicates it's DNA in preparation for division. The "textbook" stem cell don't seem to divide very often, instead they divide once to make transit amplifying cells, which divide like mad for a short period, making cells which will eventually mature and then not divide again. Why exactly older stem cells don't replentish the immune system, it sounds like that isn't known. They did say it had something to do with a growth factor, it sounds like it has little to do with DNA damage in the stem cells.

So my understanding of current stem cell theory is that stem cells won't have as much DNA damage as you would expect, and that shouldn't affect their behavior. I am not a stem cell biologist though, my understanding may be obsolete by now, and of course the "textbook" understanding of stem cells in general may or may not be true for any or all stem cell examples, such as the hematopoetic stem cells discussed here.

Re:Looking forward to Eternal Youth (1)

intrazer (449566) | more than 4 years ago | (#30958092)

This is right on the money. There is a reason that stem cells become old, they become senescent and decrease or stop their division to protect against cancer. Cellular senescence can be induced by oncogenes, or bypassed by introducing the factors found in this study.

Knocking out tumor-suppressing genes has been shown to decrease aging while at the same time increase tumor incidence.

Call me the day cancer is cured, that's the day these discoveries can be beneficial against aging.

A serious discussion, maybe? (1, Redundant)

Bovius (1243040) | more than 4 years ago | (#30953622)

Right now the comments on this topic are 85% jokes. Fun.

So, how about a serious (read: overwraught) discussion. Postulate: no greater crimes will be committed against humanity than when we discover the secrets to clinical immortality.

Re:A serious discussion, maybe? (1)

gestalt_n_pepper (991155) | more than 4 years ago | (#30953686)

Serious schmerious. What's funnier than real life vampirism or embedded cloned fetuses? Some people have *no* sense of humor....

Re:A serious discussion, maybe? (2, Insightful)

Anonymous Coward | more than 4 years ago | (#30953766)

Jokes about Howard Hughes and blood sucking seem perfectly reasonable.

Okay for the serious discussion. Obviously there's some chemical trigger involved to so the cells are responding more like young cells. It seems likely a drug could be developed that could delay age related disease. Immortality is likely an impossibility but delaying aging another decade or two would be massive. I'm starting to feel the effects of aging so getting ten years back even if it didn't extend life would be huge to me personally.

Re:A serious discussion, maybe? (1)

tonyreadsnews (1134939) | more than 4 years ago | (#30953838)

Postulate: no greater crimes

Such as growing clones of yourself for the purpose of transfusing their blood to prolong your own life.

B5 (1)

jgtg32a (1173373) | more than 4 years ago | (#30954050)

Wasn't this an episode of Babylon 5?

Re:A serious discussion, maybe? (1)

interkin3tic (1469267) | more than 4 years ago | (#30956958)

Postulate: no greater crimes will be committed against humanity than when we discover the secrets to clinical immortality.

Okay, but it's going to be a while before that's anything other than academic, and it isn't sped up by the results here. The present study has preliminary results on signaling needed to make mouse blood stem cells divide more as they did when they were younger. One day we may be able to use this knowledge to improve immune function in seniors. Cell signaling tends to be very specific to the cell type, the context. We are most likely not going to find that these same signals make all other stem cells act new, like say the stem cells in your gut or the stem cells which would repair your heart.

This line of research is not going to make your body immortal, it's probably at best going to make you less susceptible to infection as a senior citizen. Which is good, it's just not the sci-fi you're thinking of.

Lots of dirty old men . . . (1)

PolygamousRanchKid (1290638) | more than 4 years ago | (#30953626)

. . . start to act young again . . . through exposure to "young" blood cells . . .

. . . especially if those "young" blood cells are packaged in an actractive young woman.

. . . if they want to conduct a study on that, I'll be available in about 50 years . . .

Re:Lots of dirty old men . . . (1)

gstoddart (321705) | more than 4 years ago | (#30954610)

. . . especially if those "young" blood cells are packaged in an actractive young woman.

. . . if they want to conduct a study on that, I'll be available in about 50 years . . .

Dude, I'm available now. Research this important can't wait!!

Cheers

is there a similar effect in organ donations? (1)

peter303 (12292) | more than 4 years ago | (#30953682)

Although they try to match size, then relative age, sometimes out of expediency a recipient must accept a donor a decade, two, or even three decades older than themselves. Would these organs age at the donor's rate or recipient's rate? I'm guessing the answer is "in between". Depending on the tissue, the donor cells may be slowly replaced by host stem cells over the decades and become more host-like. Heart and muscle has a slow turnover rate of one percent a year. So hearts are never fully converted. Some of the earliest organs recipients have lived 3 or 4 decades.

Re:is there a similar effect in organ donations? (1)

DarthBling (1733038) | more than 4 years ago | (#30954580)

My guess is that the organ would most likely continue to age at the donor's rate and any "turnover" would be too slow to make any appreciable difference. I found this article about kidney transplants. From the extract, it basically says the age-matching helps increase the chances of survival for young recipients. http://jasn.asnjournals.org/cgi/content/full/15/4/1086 [asnjournals.org]

Re:is there a similar effect in organ donations? (1)

zippthorne (748122) | more than 4 years ago | (#30958946)

I'd imagine that the risks of taking poison every day to prevent tissue rejection far outweigh the "organ age" issue for most patients.

Old stems cells (1)

roman_mir (125474) | more than 4 years ago | (#30953718)

Old stems those cells, ha? Is that what they call it now? Since I have gone this way already let's continue with that. He, Old, stems them wicked, stems them good!

Twilight (0)

Anonymous Coward | more than 4 years ago | (#30953742)

Do the cells sparkle after this procedure?

Money for the young (1)

EvilRyry (1025309) | more than 4 years ago | (#30953762)

Screw the Red Cross, I'm going to start selling my blood to rich old people!

Chalk another one up... (1)

Angst Badger (8636) | more than 4 years ago | (#30953972)

...in the Kurzweil might not be completely full of shit even if he is crazy column.

Could be the basis for a good sci-fi... (0)

Anonymous Coward | more than 4 years ago | (#30954032)

It is the year 22XX. World leaders and major executives stopped aging over a hundred years ago. With each passing year, contamination claims more and more stockpiles of precious infant vitae. Armies are raised and butchered in the names of aristocrats elevated beyond mortality's grasp. That from above man may, instead of fleeing its footsteps, behold death's visage shall turn son against father lest the cruelties of time remind days of ephemerality.

It will bring new meaning to 'blood money'.

Gentlemen, know we know *ALL* the steps! (1)

ae1294 (1547521) | more than 4 years ago | (#30954160)

Step 1. Abduct teenage girls with proper blood type.
Step 2. Drain them of said blood, Discard remaining husk.
Step 3. Drain your tainted blood while infusing theirs.
Step 4. Hire Amazing P.R. firm to make teenage girls love you.
Step 5. Immortal Profit!

Re:Gentlemen, know we know *ALL* the steps! (1)

Belial6 (794905) | more than 4 years ago | (#30955542)

Sir, you need to reconsider your P.R. firm. With an Amazing P.R. firm, you don't need steps 1 and 2. The teenage girls will gladly give you a pint or two, and you will have plenty of them to do your fill infusion.

Re:Gentlemen, know we know *ALL* the steps! (1)

ae1294 (1547521) | more than 4 years ago | (#30958150)

Doesn't work... The teenage girls need to know you are dangerous and a murderer but that 'they' are somehow differnt and special and you aren't going to kill them...

That's the only way it seems to work.... Donno....

Umbilical Cord Blood (1)

tresho (1000127) | more than 4 years ago | (#30954300)

One painless, uncontroversial source of both young blood and stem cells is (or was) your umbilical cord blood. This is usually thrown away. Collecting it after a baby is born is trivially easy. The material is easy to preserve for decades. Costs are mostly related to storage & record-keeping.

Re:Umbilical Cord Blood (1)

ChrisMaple (607946) | more than 4 years ago | (#30957458)

The failure to get all the blood possible out of the afterbirth and into the infant reduces the health of the infant. Although it's common in modern childbirth to cut the cord as soon as possible, it's very very bad practice.

Re:Umbilical Cord Blood (1)

tresho (1000127) | more than 4 years ago | (#30957786)

The failure to get all the blood possible out of the afterbirth and into the infant reduces the health of the infant. Although it's common in modern childbirth to cut the cord as soon as possible, it's very very bad practice. Your opinion is not shared by modern obstetricians. In any case there will always be some blood retained in the veins of the umbilical cord that would otherwise go to waste.

hurry up dammit!!!! (0)

Anonymous Coward | more than 4 years ago | (#30956102)

I'm 55. With my luck I'll be 70 by the time they figure this out, and of course that will be the point of no return......

It's not vampirism- it's forced siamese twin-ism! (0)

Anonymous Coward | more than 4 years ago | (#30957016)

I saw Dr. Wager's presentation at the American Society for Cell Biology meeting this past December. They surgically attached an old mouse to a young mouse, and allowed cross-circulation to occur. They took blood samples, then later separated the mice and re-measured. It is a brilliantly simple idea (though I imagine the surgery must have been difficult). I think it's amazing! Oh, and according to the researcher apparently the mice didn't care that they were sewn together!! not sure how they determined that part...

Re:It's not vampirism- it's forced siamese twin-is (1)

ChrisMaple (607946) | more than 4 years ago | (#30957480)

Oh, and according to the researcher apparently the mice didn't care that they were sewn together!! not sure how they determined that part...

The had the mice fill out a questionaire after they were separated.

Hungarian scientists already knew that (1)

sourcerror (1718066) | more than 4 years ago | (#30962246)

Hungarian scientists [wikipedia.org] already knew that.

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