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Drug Allows Deafened Mice to Regrow Inner Ear Hair

Unknown Lamer posted about a year ago | from the turn-it-up-to-11 dept.

Medicine 80

sciencehabit writes "All you graying, half-deaf Def Leppard fans, listen up. A drug applied to the ears of mice deafened by noise can restore some hearing in the animals. By blocking a key protein, the drug allows sound-sensing cells that are damaged by noise to regrow. The treatment isn't anywhere near ready for use in humans, but the advance at least raises the prospect of restoring hearing to some deafened people."

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But... (4, Funny)

bmo (77928) | about a year ago | (#42548363)

But I have hair in my ears. I need it under my hat!


Re:But... (0)

Anonymous Coward | about a year ago | (#42548739)

That must mean you have super hearing.

Re:But... (-1, Offtopic)

fuhagaga (2812935) | about a year ago | (#42551665)

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Are you sure about that? (0)

Anonymous Coward | about a year ago | (#42548383)

I never head of this.

Sweet. (5, Insightful)

geekoid (135745) | about a year ago | (#42548387)

maybe they can cure tinnitus .

Re:Sweet. (1)

labiator (193328) | about a year ago | (#42548807)

I would love a cure for my tinnitus. 20 years of ringing in my ears is more than enough. Maybe thats why I am crazy...

Re:Sweet. (5, Informative)

Anonymous Coward | about a year ago | (#42549027)


Advice to those younger than me: WEAR FRIGGEN EAR PLUGS. It doesn't matter how dorky you think it looks. You WILL regret it if you don't.

A few years in college of night clubs, concerts, and parties was enough to set off a lifetime of tinnitus.

My ears ring constantly and it will never, ever stop.

Re:Sweet. (4, Interesting)

Hatta (162192) | about a year ago | (#42549323)

Ear plugs are the greatest. I wear Ety plugs whenver I go to a concert. These have fairly flat frequency response, and are pretty comfortable too. I was third row center at Phish with these, and had no ringing, fuzziness or any other hearing problems immediately afterwards. I've seen other LOUD concerts in small venues, P-Funk, Buckethead, shitty local punk bands, etc. with similar results. Honestly, once the levels get high enough you get more distortion without earplugs than with them.

If you are brave.... (1)

Anonymous Coward | about a year ago | (#42550099)

...the current evidence shows that Tinnitus is actually a neurological problem (the sound comes from the brain part of the ear, not the sound-sensing cells themselves) and that treatment for it (the actually effective but only available from about six psychologists in the entire world kind) is a highly-specialized variant of phantom limb pain treatment.

Based on that knowledge I decided to do some experiments with my own Tinnitus.....sitting in a relatively quiet room so the ringing was quite clear, turning on a fan so I could hear some simple white-noise too, and then mentally "pushing" the ring into the sound of the fan. I can't tell you what "pushing" really means....it is just something you have to try and do until you figure it out. It is an internal mental action in which you are trying to consciously act upon the sound itself, and change it.

After practice with this, I can (when I concentrate and do this) exercize some control over the sound. I can't make it stop completely, but I can make some of the frequencies stop (my Tinnitus is polytonal), and I can make some frequencies change into different frequencies.

It isn't much, but it is more than I was lead to believe is possible, and it is a start.

The downside is....it makes you more aware of your tinnitus in the short term (because you are mentally focusing on it and paying attention to it). If you are still in a stage where Tinnitus causes you tension or anxiety, don't try this.

Re:If you are brave.... (1)

Mike Frett (2811077) | about a year ago | (#42551733)

I think that's for some different form of Tinnitus. For instance, mine is 100% caused by excess fluid in my ear causing pressure on my nerves and such, basically an allergy. I've been to numerous Doctors and specialists. That being said, It gets so loud sometimes, not even fans or any loud noise can quell it, I have almost taught myself to ignore it but I wish it away so many times. If anyone is listening, please help us. =(

Re:If you are brave.... (0)

Anonymous Coward | about a year ago | (#42554655)

I've got tinnitus from physical abuse (mother's boyfriend attacked my biological father, got beaten up, attacked him again, got beaten up again, rinse, repeat). He caused the problem when I was 5 or 6. Since then, 31 or so years have passed, and I've learned to ignore it. Don't know how I did it, I just did.

I'm also a bass player. Unfortunately, I have great difficult matching notes, because I ignore it. I can do it by comparison sometimes, other times I can't even hold the note in my head for very long. Occasionally, i can pick the notes and just go from the fretboard (by gut feeling or knowledge) without hearing the tune for several minutes. It's really weird, and quite annoying. People think I'm tone-deaf, but I'm not.

Re:If you are brave.... (1)

gr8dude (832945) | about a year ago | (#42554759)

There is a university in Texas that works on a solution to this problem, please consider making a donation: http://www.utdallas.edu/~kilgard/tinnitus.htm [utdallas.edu]

What you write makes sense, and this is the approach taken by the researches mentioned above. I suspect that the method should work, because there are similar stories (related to other types of issues) discussed in:
- the brain that changes itself
- Dr. Ramachandran's stories about his patients

How long did it take you to learn to influence it that way?

I've done some similar experiments and I sometimes can make it less loud, just by imagining that it fades out into silence. I was never able to shut it off completely, at least not yet.

As a sufferer of mild Tinnitus (1)

arcite (661011) | about a year ago | (#42550779)

I would be willing to pay a few tens of thousands of dollars to get SILENCE back.

Re:As a sufferer of mild Tinnitus (0)

Anonymous Coward | about a year ago | (#42551771)


Re:Sweet. (1)

rtb61 (674572) | about a year ago | (#42555071)

Hate to bust your bubble moron, but every person on the planet does not damage the sight by "LOOKING AT THE FUCKING SUN", 'grr', there are many ways you can harm your sight just like there are many ways you hearing can be damaged, infection by disease just the most obvious example, this from a fellow suffer who obviously did not spend a huge amount of time in noisy environments. So a cure would still be appreciated and ear plugs do nothing for infections other than obviously increase the risk of one.

Re:Sweet. (0)

Anonymous Coward | about a year ago | (#42556953)

Or, you know, don't go to nightclubs, concerts and parties.

Re:Sweet. (3, Interesting)

mandginguero (1435161) | about a year ago | (#42549299)

it may not be a cure, but Otosound (http://www.otosound.com/) has a therapy device they are working on, and I've overheard some talk of clinical trials in Europe.

Re:Sweet. (1)

mcspoo (933106) | about a year ago | (#42549351)

As a deaf person now using Cochlear Implant(s), this would be so nice... except having a Cochlear implant probably precludes this from working for me (unless it repairs the damaged cillia in the ear as well.

Re:Sweet. (1)

evil_aaronm (671521) | about a year ago | (#42550829)

Ditto. But only in my right ear, the better one at the time. On the other hand, I'm not sure if I'd like to return to 24/7 sound. I like being able to tune things out as needed.

Re:Sweet. (0)

Anonymous Coward | about a year ago | (#42551277)

maybe they can cure tinnitus .

I hope so! My ears ring so bad, sometimes I consider making myself deaf just to make it stop.

Re:Sweet. (0)

Anonymous Coward | about a year ago | (#42555097)

Whatever you do, don't do that. As I understand it, tinnitus can be caused by the brain not shutting down the feeds from the hairs in your ear, meaning that it's getting a constant signal from them. Making yourself deaf would mean that it's the only sound you would hear - almost a Twilight Zone ending. (Had tinnitus for the last 31 years. i can sympathise with you.)

Re:Sweet. (1)

gr8dude (832945) | about a year ago | (#42554719)

I have it too and I've been experimenting with various methods of living with it. It does not bother me during the day, when there are various ambient sounds, but it becomes a problem when I am trying to fall asleep.

The method I found reasonably effective is falling asleep while playing an audiobook or podcast, for details: http://railean.net/index.php/2012/11/30/tinnitus-and-audiobooks [railean.net]

On a side note, there are quite a lot of comments posted by people with this condition. Does it feel that Tinnitus is a common "feature" among Slashdot readers? Perhaps there is something in our life-style that causes it?

I have been to a few music concerts in my life (say, 10) and I never go to discos, I am quite puzzled by the origin of my Tinnitus.

Come again? (0)

Anonymous Coward | about a year ago | (#42548397)

Didn't get any of this due to my Tinnitus.

Def Leppard fans are probably better off over time (2)

Picass0 (147474) | about a year ago | (#42548479)

... than the hearing of younger music fans listening to todays music. It's well established recording levels on newer, digitally mixed music is higher and features fewer audio low points than music from the early 90's and prior.

Also consider ear buds are the new norm for most music players, delivering sound directly to the ear canal. Your parents had walkmen with crappy foam headphones that didn't stay centered over the ear all that well.

Re:Def Leppard fans are probably better off over t (1)

codewarren (927270) | about a year ago | (#42548561)

I'm not sure that follows. Listeners compensate for both of these things by cranking up the volume only to be way over tolerance when the song goes from low point to high point or when the foam headphones shift back into place.

Which is worse for ears? Semi-loud music for 10 minutes or 10 seconds of over-the-top loud? It doesn't seem unreasonable to expect the opposite effect with flatter dynamics and a more physically stable listening device.

Re:Def Leppard fans are probably better off over t (2)

mcgrew (92797) | about a year ago | (#42550081)

Well, no, I think you're wrong and have it backwards. Listen to an old LP like Boston or Santana Abraxis and you're going to have to have it cranked to hear the soft parts while the loud parts will be LOUD. Back then, audio engineers did all they could to put that last decibel of dynamic range to use. Despite the fact that CDs have a superior range, today's engineers (like you say) have it all cranked. So you're not going to be listening to Pantera as loud as you listened to Led Zeppelin*.

That said, the only ones who are going to lose hearing from music are the musicians themselves. Most people lose their hearing from their jobs; hammers and chain saws and jet engines and factories are far louder than your super-duper high watt car stereo, and orders of magnatude louder than what comes out of an ear bud.

I'm 60 and have been listening to loud rock all my life and I have no hearing problems, although the Air Force doctors detected a 10% loss in my left ear when my enlistment was up, and I immediately knew why they had instituted the rule that the aircraft always has to be to the left of your vehicle -- it's so you only go deaf in one ear. But even after half a century of Led Zeppelin and Van halen and Ozzie and playing my own guitar, my hearing is about what it was back in 1975 when I got out of the USAF.

If you go hunting, wear ear protection. If you work construction wear ear protection. If you work in a factory it's probably mandated.

But don't worry about the music unless you're the drumer or bass player standing right in front of the speaker for four hours five nights a week. If you are, wear ear protection.

Re:Def Leppard fans are probably better off over t (1)

gstoddart (321705) | about a year ago | (#42550511)

Back then, audio engineers did all they could to put that last decibel of dynamic range to use.

But the key here is range ... as in it has highs and lows. Contrast that with someone like Nickelback, where everything is at a constant volume all the time. I found this interesting [thequietus.com] in terms of showing the differences.

I'm 60 and have been listening to loud rock all my life

And this is what's wrong with the world, old geezers are still in control of rock music. You're supposed to be listening to easy listening or Guy Lombardo by now -- you guys fucked everybody and smoked all of the good drugs, and now we can't do any of that. But it's OK, I'm dealing with it. ;-)

But don't worry about the music unless you're the drumer or bass player standing right in front of the speaker for four hours five nights a week. If you are, wear ear protection.

I don't know about that, I've been to a few concerts where the ringing lasted for hours afterwards -- and I really didn't like it. In fact, I really don't want to do it again.

I had an old manager who said he's been to so many concerts that most things sound like the adults in a Peanuts cartoon ... an indistinct "wah wah waaah". :-P

If you're listening to headphones loud enough to be causing damage, well, that's your choice. But for concerts and the like? I'll stick with the earplugs myself. It doesn't take all that long to cause damage, and the few times I've had ringing which lasted hours afterwards taught me it's not something I'd like to repeat.

Re:Def Leppard fans are probably better off over t (1)

mcgrew (92797) | about a year ago | (#42557691)

But the key here is range ... as in it has highs and lows. Contrast that with someone like Nickelback, where everything is at a constant volume all the time.

That was exactly my point. Listen to Nickleback at three and you;ll hear every note. Listen to Zeppelin's "The Ocean" (on LP, they stupidly compressed the dynamics on the CD) and if it isn't cranked to ten, the soft part in the middle is inaudible. Which is why the older music would have been harder on the ears.

And this is what's wrong with the world, old geezers are still in control of rock music. You're supposed to be listening to easy listening or Guy Lombardo by now -- you guys fucked everybody and smoked all of the good drugs, and now we can't do any of that.

LOL! Actually, today's reefer is far better than all but the best back in the seventies, and you really wouldn't want to smoke elephant tranquilizer (phencyclidine). As to music, well, it's not our fault that we were so good at making music.

I had a discussion with my dad once, who opined that the music of his youth (Glen Miller, Tomy Dorsey) was the best music recorded, but he's wrong. My generation never listened to those old guys and my dad's only 21 years older than me. OTOH today's twentysomething are still listening to the same music I did (and still do) forty years ago.

Of course, back then we used joints and pipes and bongs, and it was a social thing. Today's youth (and even most geezers) use one hitters. I far prefer the old way there.

I don't know about that, I've been to a few concerts where the ringing lasted for hours afterwards

Fire a 20 guage shotgun, just one round, and your ears will ring for hours. Imagine if your job site were as loud as that concert? Most factories are louder. Most everyone I know who's my age and worked in construction or in a factory wear hearing aids.

Re:Def Leppard fans are probably better off over t (1)

Samantha Wright (1324923) | about a year ago | (#42550273)

Because the decibel scale is logarithmic, hearing damage is not something most music listeners subject themselves to except at concerts and dance parties. People are much less likely to turn up their headphones until they feel pain than they are to go to a concert and accept a bit of pain in exchange for the experience.

Re:Def Leppard fans are probably better off over t (1)

ozydingo (922211) | about a year ago | (#42556877)

It might be true that most listeners aren't subjecting themselves to great damage over their headphones, but even then I think you're drawing too quick a conclusion with too little data. And certainly on the (not-too-uncommon) instances when I can listen to the music of the guy sitting a few seats down from me on the bus through his headphones, I think there's likely some damage going on there.

Note also that the threshold of pain for hearing is often measured well above where damage starts to occur. Maladaptive, maybe, but it seems to be pretty true nonetheless. And if I'm not mistaken, those studies were done before the current research coming out showing that even when loud sounds do not cause permanent shifts in hearing thresholds, permanent nerve damage is still being done. Thresholds for pain are often well above 100 dB SPL (for broadband stimuli), while damage can be done with prolonged exposure well below that.

Lastly, a minor point, but I don't know what the logarithmic nature of the dB scale has to do with any of this. It's just a scale, a way to place arbitrary numbers on physical phenomena.

Re:Def Leppard fans are probably better off over t (1)

Samantha Wright (1324923) | about a year ago | (#42559823)

Alright. I dug up some further numbers. Most sources recommend keeping exposure below 85 dB. Prolonged exposure to 90 dB and above can cause hearing loss, and pain begins at 120-125 dB. With the right headphones, the old iPod Nano puts out 90 dB at half volume, which is enough to cause permanent damage after eight hours of continuous exposure. So, yeah, you're thoroughly right. Forget the logarithmic thing; I had that backwards. Definitely been too long since I looked at sound stats.

Don't be so quick to judge based on bleeding audio, though; at least not unless you get a good look at the headphones in question. The listener might not be wearing the headphones properly (hence causing leakage) or the headphones may have an open-back design meaning they leak more than usual. I have a pair of (rather old) AKG K240s which do this, and because they're very bulky people assume they must be operating at an exceptionally powerful level—but it's just the lack of a solid casing around the drivers.

Re:Def Leppard fans are probably better off over t (1)

ozydingo (922211) | about a year ago | (#42560211)

Of course you're right, the bleeding audio comment was more of a "damn kids and your music" than a scientific remark. It would actually depend on everything from the design of the headphones to the shape of the listener's ear and its orientation relative to me. I still think it's a reasonable intuition when it's coming over iPod earbuds, leaky as they may be.

Re:Def Leppard fans are probably better off over t (1)

Cyrano de Maniac (60961) | about a year ago | (#42555381)

I am a middle-aged fan of Def Leppard, a mild tinnitus sufferer (starting as early in childhood as I can remember -- so probably neurological), and a weekend warrior front-of-house sound engineer. I think you are completely correct, and not just because of the dynamic range issues you mention.

Despite being a fan since the Hysteria years, it was only about a year and a half ago that I first went to a Def Leppard concert. Knowing that there could be problems and that I value my hearing, I made sure to bring decent ear protection. The sound for the opening act (Heart) was brutal -- piercing, obnoxious, and you couldn't make out lyrics except where you already knew them. I put in my ear plugs and sat down, waiting for the spectacle to be over.

That all changed when Def Leppard took the stage. The music was loud, but everything was also very clear and pleasantly equalized and mixed. It was easily the best mixed live show I've ever had the privilege of hearing, bested perhaps only by Phantom of the Opera and Les Miserables touring companies (which aren't dealing with nearly as high of sound pressure levels). Willing to risk it for the experience of hearing my favorite rock band live for the first time in my life I didn't use hearing protection at all, and while my hearing was certainly desensitized until the next morning, there was never a single moment of pain.

I love my weekend hobby as a live sound guy, and the highest complement I've ever received (from a pro) for a rock-style show was that they were impressed that everything felt nice and loud, and they were so happy that their ears didn't hurt afterward. That's a difficult thing to achieve, so I have nothing but admiration for whoever (most likely Ronan McHugh) mixed Def Leppard's show that night.

Hair cells are not hair. (1)

Antipater (2053064) | about a year ago | (#42548493)

There is no hair in the inner ear. Even the submitter didn't RTFA, apparently...

Re:Hair cells are not hair. (0)

Anonymous Coward | about a year ago | (#42548591)

Well, actually, ever looked inside an arab's ear ??

All a matter of time.... EXCEPT... (5, Funny)

Anonymous Coward | about a year ago | (#42548513)

Deaf people re-growing inner ear parts...
Blind people re-growing eyes and optic nerves...
Alcoholics re-growing a liver...
Soldiers re-growing limbs....

It's all possible, given time to develop these things... EXCEPT...

I just can't grow a set of balls and stand up to my wife!

Re:All a matter of time.... EXCEPT... (0)

Anonymous Coward | about a year ago | (#42549277)

It's all possible, given time to develop these things... EXCEPT...

I just can't grow a set of balls and stand up to my wife!

Just tell her you need them for guy's night out, then conveniently forget to return them when you're finished showing them off at the pub.

Re:All a matter of time.... EXCEPT... (0)

Anonymous Coward | about a year ago | (#42551331)

They offer sex change operations these days to convert from female to male. But she may prefer the rug instead of a sausage.

Super Powers (0)

Anonymous Coward | about a year ago | (#42548517)

Drug double dosis by accident and get superauditive powers, then become the paladin of the neighbour gossips.

Alternate use. (4, Insightful)

SuricouRaven (1897204) | about a year ago | (#42548615)

Could this be used to reverse or at least slow down age-related hearing loss? People are living so much longer than they used to, so we need every medical trick we can devise to lessen the detriments of age.

Re:Alternate use. (1)

tokencode (1952944) | about a year ago | (#42548851)

Last I checked, old people do not need any help growing more hair in their ears ... seriously though, I would guess that this kind of damage is one of the leading causes of age-related hearing loss so yes it would probably help in at least some cases.

Re:Alternate use. (2)

Alphadecay27 (1277022) | about a year ago | (#42549597)

They administered the drug the day after the damage occurred. The article states that it is not clear whether it would be effective for long term hearing loss. The actual study is behind a paywall but the highlights don't seem to indicate any perceived limitation based on time. They state that:

hair cell generation resulted from transdifferentiation of supporting cells.

My (completely uneducated) guess would be that it should restore some level of hearing in age related cases since it is inducing new cell growth not just healing or multiplying existing cells.

Re:Alternate use. (2)

mcgrew (92797) | about a year ago | (#42550961)

Could this be used to reverse or at least slow down age-related hearing loss?

I could be mistaken, but I think what most call "age related" just means that the damage to your ears over the years is cumulative. If I'm right, then yes, it would.

People are living so much longer than they used to

Only statistically; individuals are still having heart attacks in their forties and cancers even among children. The reason the statistics say we're living longer is because some diseases and injuries that would previously have been fatal are more easily treated or have been wiped out, industry has been made to be safer, cars are far safer (note that fatalities have been dropping yearly for decades). OTOH my grandmother was born in 1903 and lived a hundred years.

Statistics only give the odds; there are always outliers. An example is my great uncle, who started smoking at age 12, quit at age 82 and died ten years later. Statistics taken like most people take them would seem to suggest that my uncle was an impossibility, but statistics is just a game of the odds.

Re:Alternate use. (1)

cusco (717999) | about a year ago | (#42553109)

Doesn't even require damage to the ears in many cases. There can be a hereditary component to hearing loss (which I've been unlucky enough to inherit) which is progressive and irreversible. Live in a nice quiet environment your whole life and you can still lose your hearing.

A major component in the rise in average life expectancy is reduced child and infant mortality. If a family had 10 kids, lost 5 of them in infancy, and the rest lived to all be 100 the average life expectancy for the family is still only 50 years.

Re:Alternate use. (1)

Neil Boekend (1854906) | about a year ago | (#42555689)

The age-statistic is even less usefull: Many infant deaths have been solved. This bumps up the average age a lot, without raising the maximum age. Aging problems are a result from the maximum age, not simply the average. Better would be to use the average age of people who get older than 50 (for example).
BTW: The maximum age is higher than it was 100 years ago, but not as much as the average age.

Re:Alternate use. (1)

techno-vampire (666512) | about a year ago | (#42552493)

Not everybody with noise-related hearing loss got it from concerts. I got mine from exposure to outbound shore bombardment [wikipedia.org] back in Tonkin Gulf in '72, making it service connected. Free hearing aids are nice, but I'd rather have my hearing back. I hope they get this working in humans in time for me to benefit, as well as a friend [jerrypournelle.com] with similar issues from Korea.

At a concert I went to .... (2)

sandytaru (1158959) | about a year ago | (#42548633)

The tech guys had a big meter with numbers on it that seemed to also be "dancing" in time with the music. Mostly wobbling between 110 and 118 with some fractions in between. I had earplugs in, but after a while I realized it was ensuring that the decibels never got above 120, the point at which permanent hearing loss occurs.

Re:At a concert I went to .... (0)

Anonymous Coward | about a year ago | (#42549479)

your ears can be damaged at leves as low as 85dbA if the durration of the exposure is long enough. http://www.osha.gov/SLTC/noisehearingconservation/

Re:At a concert I went to .... (0)

Anonymous Coward | about a year ago | (#42549565)

There is no "point" in decibels at which permanent hearing loss occurs. It's cumulative. If you spend enough time listening to 110 dB music, you will definitely get permanent hearing loss.

Re:At a concert I went to .... (1)

clockwise_music (594832) | about a year ago | (#42552469)

Good job on the earplugs.

But the reason why they had the volume meter is not because they care about your hearing, but for legal reasons. There is normally a restriction on the maximum volume level allowed. Some venues even have an automatic cutoff so that if the volume stays above a particular threshold for a particular amount of time, BOOM, OFF GOES YOUR PA. Terrifying when you're the sound person doing a big gig that people have paid lots of money for.

Meh. (0)

Anonymous Coward | about a year ago | (#42548703)

For sheer volume of noise, Def Leppard can't hold a candle to Blue Cheer...what?

Yeah, would be nice to get my hearing back after spending most of the late '70s and early '80s at concerts losing it...not gonna hold my breath, though.

Eh? (1)

digitalhermit (113459) | about a year ago | (#42550763)

I'm reading this two minutes after pulling apart a Peavey RAGE guitar amp and showing my daughter how to play Marissa Paternoster's shred near the middle of "I Don't Mind It".

Too late (1)

jamesh (87723) | about a year ago | (#42550803)

Too late for those of us from the Def Leppard era (I was never a fan, but there was lots of other loud music going on). Might be just in time for the kids of today from the One Direction era (Ha Ha - that's how your generation is going to be defined!!!)

Def Leppard fan with hearing damage...... (1)

antsbull (2648931) | about a year ago | (#42551115)

Very relevant post to me - massive Def Leppard fan (35 years old) and have mild tinnitus in one ear from getting headbutted in a soccer game which also burst my ear drum. It would be awesome if there was something they could do to fix my hearing - the ringing is very high pitched, so gets lost amongst ambient sounds, but the real annoying thing is that semi-loud music now distorts in that ear for some reason. I still remember going to concerts in the early 90s like White Zombie where they had posters up all over the walls warning that they weren't responsible for any hearing damage concert goers may suffer. There were concerts where your ears had loud ringing noises in them for 3-4 days after the concert. I always wear ear plugs these days.

Re:Def Leppard fan with hearing damage...... (1)

nopainogain (1091795) | about a year ago | (#42553239)

Whaaaaat? lol, i stood in front of my share of speakers too man.. (38 year old guitarist and metal fan here)

Re:Def Leppard fan with hearing damage...... (1)

ckedge (192996) | about a year ago | (#42555077)

Might not be relevant to me. :(

There's a huge fraction of Tinnitus sufferers whose Tinnitus is *not* caused by loud music. They can tell because the hearing loss is in the mid-range, whereas loud music loss is at the high and the low ends. In our cases it develops in your 30's to 50's -- with no known cause. They figure it may have more to do with the brain!

My ability to hear things is not actually impaired when they test it. When they test it they can't see a difference between the two ears. But in one ear sounds SOUND different. They sound muffled and/or distorted (despite testing saying that my raw sensitivity is not affected) . If I lie in bed with right side of my head down, the ambient noise "sounds dulled", when I turn my head and put the other side down I can hear all the crisp little bits of the ambient noise. Putting a freshly poured pepsi up to each ear, sounds drastically different between the two. No known cause. The ringing is likely as much a symptom as the dulled sharpness.

The docs say it's clearly related to something to do with modern society, as the incidence rates are rising.

What about genetic hearing loss? (1)

MetricT (128876) | about a year ago | (#42552869)

I'm hard of hearing. It's not because of noise, I actually can't stand loud sounds at all. It just runs in the family. I've got it, so does dad, so did grandpa, and so on.

While *any* advance in restoring hearing is nice, how about concentrating on helping those of us who never had a choice, rather than those who just stood too close to the speakers?

But if ear hair improves hearing (2)

nopainogain (1091795) | about a year ago | (#42553211)

how are so many aged men with fur-coats growing out of their ears so hard of hearing? (this replaces my bad joke based solely on the headline which was "are you sure you didn't just turn the mice into middle-aged-men?")

More Slashdot sociopaths... (0)

Anonymous Coward | about a year ago | (#42553241)

Yes, sure is 'fun', isn't it, torturing animals so that worthless humans (including the psychopaths who enjoy torturing them for a 'job') can benefit.

Look at the ridiculous comments, what a bunch of saddoes you are. The only living beings who will ever matter to you in your pathetic lives are those who directly benefit YOU, i.e. YOUR wife, YOUR children, etc.etc. and only because YOU get something out of them.

When was the last time you couldn't sleep because you were thinking about innocent animals being tortured in factory farms, or in vivisection laboratories?
Cue laughable attempts by the aforementioned sociopaths to convince me that they aren't sociopaths...

92% of drugs which work in animal experiments FAIL in human experiments (AKA 'clinical trials'). NO drugs get to market without passing human experiments (AKA 'clinical trials'). An 8% success rate means that animal experiments are medical fraud. Which animal is the correct model for human disease X? We don't know until AFTER the human experiments have been done? Which means ALL animals experiments are a fraud.

Sounds good (1)

HHealthy (2803519) | about a year ago | (#42577877)

This is really good. As of now we can say that some useful transdifferentiation is on the way. Of course this woudnt be so easy in organs with a much complex structure, like the retina, but still a great step forward. We already know that some cells can migrate in the adult brain, like those renewed for smelling. It may only take time for 1+1=2! For funding, research and peer finding please refer to the non-profit Aging Portfolio.
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