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Nanoparticle Exposure Could Disrupt Immune Cell Function

Soulskill posted about 9 months ago | from the finding-new-and-creative-ways-to-harm-ourselves dept.

Biotech 31

MTorrice writes "A new study suggests there's more to nanoparticle toxicology than cell life and death. Although immune cells treated with iron oxide particles appeared healthy in standard toxicology tests, they struggled to perform one of their key jobs: engulfing pathogenic bacteria. The researchers wonder if exposure to significant levels of the nanoparticles could lead to dysfunction in people's immune systems."

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31 comments

Turn that around (4, Interesting)

Spy Handler (822350) | about 9 months ago | (#44312013)

researchers should wonder if exposure to nanoparticles will disrupt cancer cell function or antibiotic-resistant superbug function and devise a strategy to shoot them with the appropriate nanoparticles.

Re:Turn that around (0)

Anonymous Coward | about 9 months ago | (#44312049)

Or wonder if this is the true cause of aids. Not the barely detectable HIV.

Re:Turn that around (0)

Anonymous Coward | about 9 months ago | (#44312155)

Or wonder if this is the true cause of aids. Not the barely detectable HIV.

HIV is very well studied and quite detectable when your viral load is high enough.

Pictures of HIV [va.gov]

Pictures of HIV [phys.org]

HIV isn't some exotic particle that scientists theorize *may* exist in some dimension.
It is something that we've observed with our own eyes and can replicate with (far too much) ease.

Don't spread nonsense about HIV not being the cause of AIDS unless you've got some peer reviewed research to back it up.

Re:Turn that around (0)

Anonymous Coward | about 9 months ago | (#44316097)

I think you should re-read the post you're replying to, he wasn't spreading "nonsense about HIV not being the cause of AIDS".

You thought police should fuck right off.

Re:Turn that around (1)

Rhywden (1940872) | about 9 months ago | (#44312185)

I wonder if you actually spent two seconds thinking about this our simply spouted off another tangent for your favourite conspiracy theory.

Seriously, if it were nano particles it wouldn't explain why:
- it's a sexually transmitted disease (through exposure to blood)
- it has a variable dormancy period
- why it gets more serious with time passing (nanoparticles would, just like heavy metals, eventually leave the body)
- why it's treatable with antiviral medicine.

Re:Turn that around (0)

Anonymous Coward | about 9 months ago | (#44316123)

I wonder if you actually spent two seconds thinking about this our simply spouted off another tangent for your favourite [sic] way to bash people with propaganda based terminology (conspiracy theory).

How about if HIV gave off nano particles?

I wish the capital "S" science crowd would get the idea into their heads that claiming "rationality" doesn't give you the right to act like an ass to everyone you disagree with.

Re:Turn that around (1)

Anonymous Coward | about 9 months ago | (#44312239)

yes

http://www.ncbi.nlm.nih.gov/pubmed/?term=nanoparticles+cancer

and yes

http://www.ncbi.nlm.nih.gov/pubmed/?term=nanoparticles+bacteria

Re:Turn that around (1)

Anonymous Coward | about 9 months ago | (#44312259)

A study was just released describing a potential link between MS (an immune disorder) and Iron deposits
http://www.thealmagest.com/2013/07/gray-matter-damage-linked-to-multiple-sclerosis/

Re:Turn that around (0)

Anonymous Coward | about 9 months ago | (#44313001)

To this day I wonder why phage therapy never caught on in the US...

No Need (1)

caspy7 (117545) | about 9 months ago | (#44314711)

No need to turn it around, we can have both.
But if it turns out the cure is worse than the cause, these are good questions to answer.

Re:Turn that around (0)

Anonymous Coward | about 9 months ago | (#44315861)

Yes, but they will also kill the patient in the process.

We already have a solution that very elegantly cures cancer: Gene therapy, using modified AIDS viruses that "infects" white blood cells with a gene code that tells them that those cancer calls are to be attacked. 3 days of fever, and the cancer is gone. (Remember the news story? The last time I checked, they already had cured 8 patients of lung cancer that way.)

Besides: Anyone who remembers how the whole asbestos thing went, isn't the least bit surprised that nanoparticles WILL cause lots of really nasty diseases. It's almost a given. A guarantee. And it's pretty obvious, if you understand how the body works.

Finally, somebody understands. (1)

Anonymous Coward | about 9 months ago | (#44312147)

Nanoparticles that are the size of mineral molecules will displace the essential minerals from their place in the enzymes that make up the function of the immune system. This is the same problem with heavy metals. The implication is we will probably never be able to successfuly manipulate the body's immune system to any significant degree. Anybody who tells you otherwise is trying to sell you the Brooklyn Bridge.

If you want to cure degenerative illness, then take out heavy metals and don't poison yourself with chemicals. This is a good as it gets.

Re: Finally, somebody understands. (2)

Gilmoure (18428) | about 9 months ago | (#44312325)

Exactly! As things stand now, that's as good as it'll ever be. Human beings are not exactly known for making advances in areas where everyone knows advances can't be made.

Re: Finally, somebody understands. (0)

Anonymous Coward | about 9 months ago | (#44314093)

If degenerative illness could be "cured" it would have been done by now, don't you think? I mean really, I'm old. I'm an old person. Crooks, er, "researchers" have been telling us there is a cure for cancer, ALS, MS due any year now since I was a child. Just give us all your money. Which, if you haven't noticed, is happening to an *alarming* number of people during the horrible course of their degenerative illnesses.

Ok, here's an idea for an advance: Prevent the transfer of heavy metals from pregnant mothers to the fetus. That way you prevent many of the heart-breaking congenital illnesses that currently plague us. But that could be a bad thing. A whole lot of people would be born healty. Reduced need for the health care gravy train. All the Bernie Madhoffites on Wall Street might not like that idea.

Hey Wall Street: Big Hat, No Cattle.

Re:Finally, somebody understands. (1)

wonkey_monkey (2592601) | about 9 months ago | (#44312641)

don't poison yourself with chemicals.

Damn straight. From now on I'm not letting any chemicals into my body!

Re:Finally, somebody understands. (0)

Anonymous Coward | about 9 months ago | (#44312879)

Especially dihydrogen monoxide! That shit is deadly!

Re:Finally, somebody understands. (2)

bdwebb (985489) | about 9 months ago | (#44312699)

Hmm...you lost me when you said we won't be able to successfully manipulate the body's immune system...what about vaccines? That is pretty effective manipulation, sans-bridge.

Re:Finally, somebody understands. (0)

Anonymous Coward | about 9 months ago | (#44313927)

I said degenerative illnesses, ie. ALS, Altzheimers... cancer.

Remember that many nanoparticles occur naturally (1)

Ambassador Kosh (18352) | about 9 months ago | (#44312825)

It is great that we are learning this stuff. However nanoparticles are not in general good or bad, they are an entire class of molecules that are on the scale of a nanometer. Some will be good, some will be bad and the more we can learn about this the better off we are. There are some we have found that tend to concentrate in certain cell types and may help or harm the cell depending on what they are.

This is an area that needs a massive amount of effort and research. I suspect that many of the illnesses that people have now are actually caused by naturally occurring nanoparticles and that the cures for them is likely to be found in other types of nanoparticles.

Re:Remember that many nanoparticles occur naturall (0)

Anonymous Coward | about 9 months ago | (#44314133)

"This is an area that needs a massive amount of effort and research."

Big Hat, No Cattle

BAN IT ALL NOW (0)

Anonymous Coward | about 9 months ago | (#44312843)

Or adopt reasonable precautions as we do for any other hazardous substance.

Re:BAN IT ALL NOW (1)

Anonymous Coward | about 9 months ago | (#44314455)

Thats just it, we don't "adopt reasonable precautions as we do for any other hazardous substance". You wonder why our country is plaged by chemically induced illnesses? Because congress made it legal to do so in 1976.

Lookup the Toxic Substances Control Act of 1976. A complete travesty. Congress sold your health and pocketed the money and kissed babies after they kissed Monsanto's ass.

Now you know why cancer won't be cured any time soon.

This is just as good a reason to riot than anything else I've seen recently.

in other news (1)

stenvar (2789879) | about 9 months ago | (#44313499)

Exposure to liquids can cause poisoning, and exposure to solids can cause bullet wounds. We should avoid all liquids and solids, just to be sure.

Pills (1)

Misagon (1135) | about 9 months ago | (#44314221)

Yet, practically all types of medicinal pills still contain nanoparticles of Titanium Dioxide, used only for colouring the pills white.
It is not like you have the option of choosing another brand that does not have nanoparticles. Often the prescribed medicine is the only one available with the active ingredient ... or all the brands contain TiO2.
TiO2 is also in many brands of sunscreen, but in this case it is much easier to choose another brand.

Re:Pills (0)

Anonymous Coward | about 9 months ago | (#44314741)

"It is not like you have the option of choosing another brand that does not have nanoparticles"

Oh, yes you do. It depends on the manufacturer. Try Now Foods, Neesby, Thorne Research, Integrative Theraputics, Jarrow, Solgar, Klaire...
Just don't buy your vitamins from WalMart.

duh iron not good... (0)

Anonymous Coward | about 9 months ago | (#44314825)

Wow what a finding metalic iron not good for the body?

Get a clue hippies.

I know you won't post but you are still an idiot hippie... CO2 is a poison plants love and you exhale...

HA ha..

Miracle Material (1)

ThatsNotPudding (1045640) | about 9 months ago | (#44316245)

Once upon a time, asbestos was considered a miracle too.

Material that can effortlessly pass thru the blood / brain barrier are being used in more and more products with no foresight whatsoever (commerce!). This will not end well.

Re: Miracle Material (-1)

Anonymous Coward | about 9 months ago | (#44317279)

Don't believe the hype. As usual this "science" has confused correlation with causation. Too many scientists these days are incompetent and simply looking for funding By making ridiculous claims hoping they stick. How else can you explain hoaxes like global warming and evolution?

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