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Gene Therapy Creates Strong Super-Rats

timothy posted more than 10 years ago | from the pizza-with-nietzsche-cheese-please dept.

Biotech 414

srstoneb writes "The AP is reporting about a gene therapy study in which muscle tissue in rats is modified to grow at an accelerated rate. The researchers are mainly interested in combating muscular dystrophy, but obviously there are other potential applications, both good and bad, for a treatment which makes you stronger. Athletic ethics are addressed in the article (it's in the sports section, after all), and rec.arts.comics.marvel.universe regular Tom Galloway -- who posted the link there, where I saw it -- made a comparison to the 'super-soldier serum' that created Captain America. Based on the article, a vaguely Wolverine-like healing factor is another benefit as the therapy allows faster recovery from injury. We already had a non-powered superhero reported last year. Who knows what the future may hold? ^_^" (And that's not the only natural-born superhero.)

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Super Strong Frosty Piss (-1, Troll)

Anonymous Coward | more than 10 years ago | (#8302679)

Not gene therapy

Pee therapy!!!

Time for the mutant holocaust (-1, Offtopic)

Anonymous Coward | more than 10 years ago | (#8302681)

BOO!

GNAA Leaks Windows 2000 Source code (-1, Troll)

Anonymous Coward | more than 10 years ago | (#8302682)

GNAA Leaks Windows 2000 Source code
by GNAA staff

As previously reported here [slashdot.org] , source code to Microsoft's latest operating system has been stolen.

So far, nobody claimed responsibility for the act, and Microsoft is denying it even happened. But you know better than that! GNAA 0wnz you.


We will be right back after this commercial break!
According to Google Zeitgeist [google.com] , there are about 80% of Internet Explorer 6 [microsoft.com] users. The only platform supporting Internet Explorer 6 is, of course, Microsoft Windows. These statistics are consistent with the earlier presented graphs of the operating systems used to access Google, with the Windows family consistently taking the top 3 ranks. Out of remaining 20%, the split is even between MSIE 5.5, MSIE 5.0, both Windows-only browsers. Netscape 5.x (including Mozilla) counts for only a measly 5% of browsers used to access Google. As you can see from the graph, this sample was calculated starting from March 2001 until September 2003.
According to Google Zeitgeist [google.com] , there are about 80% of Internet Explorer 6 [microsoft.com] users. The only platform supporting Internet Explorer 6 is, of course, Microsoft Windows. These statistics are consistent with the earlier presented graphs of the operating systems used to access Google, with the Windows family consistently taking the top 3 ranks. Out of remaining 20%, the split is even between MSIE 5.5, MSIE 5.0, both Windows-only browsers. Netscape 5.x (including Mozilla) counts for only a measly 5% of browsers used to access Google. As you can see from the graph, this sample was calculated starting from March 2001 until September 2003.
And now we return to our scheduled broadcast...

.________________________________________________. fucking
| ______________________________________._a,____ | CmdrTaco
| _______a_._______a_______aj#0s_____aWY!400.___ | will
| __ad#7!!*P____a.d#0a____#!-_#0i___.#!__W#0#___ | he ever learn that
| _j#'_.00#,___4#dP_"#,__j#,__0#Wi___*00P!_"#L,_ | GNAA is totally
| _"#ga#9!01___"#01__40,_"4Lj#!_4#g_________"01_ | unstoppable? Teamed
| ________"#,___*@`__-N#____`___-!^_____________ | up with the other troll groups,
| _________#1__________?________________________ | GNAA will absolutely own
| _________j1___________________________________ | the shitty place that is slashdot.
| ____a,___jk_GAY_NIGGER_ASSOCIATION_OF_AMERICA_ | Just remember, the longer the lines are,
| ____!4yaa#l___________________________________ | the smaller CmdrTaco's penis.
| ______-"!^____________________________________ | This logo is (C) 2003, 2004 GNAA
` _______________________________________________' [1] [idge.net]

(C) GNAA 2003, 2004


Gene Therapy Causes Strong Superniggers (-1, Troll)

Anonymous Coward | more than 10 years ago | (#8302687)

Propz to my niggaz in the GNAA.

I love you guys with ever fiber of my cockmuscle.

EARLY POST FOR JIN WICKED! (-1, Offtopic)

Anonymous Coward | more than 10 years ago | (#8302693)

I love you sweetie!

Great, thats all we need... (5, Funny)

myowntrueself (607117) | more than 10 years ago | (#8302697)

Rats with "vaguely Wolverine-like healing factor".

Wonderful.

I can see the pest control guys kitting up with miniguns and RPGs.

Re:Great, thats all we need... (-1, Troll)

Anonymous Coward | more than 10 years ago | (#8302719)

Re:Great, thats all we need... (0, Troll)

vanillacoke (646623) | more than 10 years ago | (#8302897)

MINE EYES THEY BURN!

Re:Great, thats all we need... (5, Funny)

originalTMAN (694813) | more than 10 years ago | (#8302790)

Well, most of us have [residentevil.com] been [planetquake.com] training [planetdoom.com] for [halo.com] this [planethalflife.com] day [microsoft.com] for quite a while. I think the world will be safe.

Re:Great, thats all we need... (4, Funny)

Borg453b (746808) | more than 10 years ago | (#8302800)

Yes - I knew my l337 skillz would come to good use eventually. 'I frag purely to save the world and impress the chicks'

Re:Great, thats all we need... (-1, Flamebait)

Anonymous Coward | more than 10 years ago | (#8302867)

get the fuck off of this site you danish blondie-fag

!
!!
!!!

Almost too embarrassed to say but.... (4, Funny)

nano2nd (205661) | more than 10 years ago | (#8302698)

I for one welcome our new mutant rat overlords.

Really? (0, Redundant)

Arcanix (140337) | more than 10 years ago | (#8302753)

I don't.

Re:Almost too embarrassed to say but.... (2, Funny)

NanoGator (522640) | more than 10 years ago | (#8302767)

Why'd this get +5? Is there like a reference to Hitchhiker's Guide or Doctor Who that I'm missing?

Re:Almost too embarrassed to say but.... (4, Informative)

alien_blueprint (681111) | more than 10 years ago | (#8302791)

This is an old /. "joke." [wikipedia.org]

At this point I'll re-use another tired old catch-phrase, which is described on the very same Wikipedia page - "you must be new here" ;)

Re:Almost too embarrassed to say but.... (2, Insightful)

NanoGator (522640) | more than 10 years ago | (#8302840)

Sorry, I wasn't clear enough in my original post. It should have been more like "in light of all the overuse of this joke, why was it...".

Thankfully the mods came and fixed it. *WhEw*

Re:Almost too embarrassed to say but.... (0)

Anonymous Coward | more than 10 years ago | (#8302838)

It didn't get a +5. It had a +1 humor (though someone's modded it back down). The user must be a friend, a friend of a friend, or you've set a bonus for humor.

Re:Almost too embarrassed to say but.... (1)

alien_blueprint (681111) | more than 10 years ago | (#8302846)

No, it was briefly +5, but then got modded back down.

Re:Almost too embarrassed to say but.... (0)

Anonymous Coward | more than 10 years ago | (#8302876)

Wow, that many people modded it down?

If ever there was a time when the Overload joke is on topic, that was it... :)

Re:Almost too embarrassed to say but.... (2, Funny)

alien_blueprint (681111) | more than 10 years ago | (#8302909)

If ever there was a time when the Overload joke is on topic, that was it... :)

I was just thinking the same thing. At first glance, the first one should have been modded up (but perhaps not all the way to 5), and the rest modded down as "redundant." However, a straightforward application of this joke can't really be justifiably modded up anymore, even if giant ant overlords really were taking over. It's just not funny, informative, or insightful now.

So in conclusion I suppose I'm saying that I for one welcome our new moderator overlords ...

wow. (-1, Troll)

Anonymous Coward | more than 10 years ago | (#8302700)

cunt sucking is crazy.

Someone will be happy (3, Funny)

fullofangst (724732) | more than 10 years ago | (#8302701)

Good news for 'pro' wrestlers then!

Splinter first, turtles later (4, Funny)

Anonymous Coward | more than 10 years ago | (#8302702)

Progis Riport 1.

Algernon kickd me in th nuts! It is sawr.

Re:Splinter first, turtles later (0)

Anonymous Coward | more than 10 years ago | (#8302728)

Oh at first I though this was one of those retarded "frist psot" trolls, but then elementary english class came to mind, and I nearly pissed my pants laughing.

Kudos.

MOD PARENT "FUNNY" (4, Informative)

GiveMeLinux (713432) | more than 10 years ago | (#8302745)

Reference is to "Flowers for Algernon."

Ugh, that smilie (-1, Offtopic)

Anonymous Coward | more than 10 years ago | (#8302703)

^_^ needs to die, now.

Re:Ugh, that smilie (-1, Offtopic)

Anonymous Coward | more than 10 years ago | (#8302787)

@_____@;;

Governator (3, Funny)

filtur (724994) | more than 10 years ago | (#8302708)

Now the rats can run for Governor of California

I'm sorry, I'll post something useful eventually!

Dateline 2020... (4, Funny)

heironymouscoward (683461) | more than 10 years ago | (#8302709)

Superrat "Mitee Mus" runs for governor of the Democratic Republic of California, winning 63% of the votes. Standing 7'3" tall, weighing 120kg and gifted with an IQ of 192, Mitee Mus told reporters "Now I can get to the real business of building nice warm nests for every Californian". He is married to the cousin of a Kennedy.

Re:Dateline 2020... (0)

Anonymous Coward | more than 10 years ago | (#8302732)

Wow, seeing as how there are less than 7 million patents, and using crude interpolation, I estimate your sig patent will be issued sometime after 3000 AD.

Re:Dateline 2020... (2, Funny)

heironymouscoward (683461) | more than 10 years ago | (#8302807)

With full automation of the USPTO, planned in 2005, patents will be issued directly to pre-approved parties without the tedious business of examination. This will allow the USPTO to increase its turnover by 5000% and will reach the 10bn mark in late 2007. The pre-approval process will also be streamlined so that a single large contribution to the political party in power suffices to purchase bulk patents.
Breath now while it's still Free!

Re:Dateline 2020... (2, Funny)

radicalskeptic (644346) | more than 10 years ago | (#8302786)

Wow, for some reason I can't help but be reminded of FATMOUSE [fatmouse.tk]

Yeah, I know, it's... weird...

Re:Dateline 2020... (1)

originalTMAN (694813) | more than 10 years ago | (#8302944)

Brain [frogspace.net] must be pissed.

Super Rats \o/ (-1, Redundant)

Anonymous Coward | more than 10 years ago | (#8302710)

I for one welcome our Super Rat overlords.

...Ratman (0, Redundant)

derphilipp (745164) | more than 10 years ago | (#8302711)

The new superhero:
Superrat
He lives in the sewers, fights evil crocodile-ninjas.

And his only weakness is his secret addiction to cheese.

Master Splinter ? (Turtles)

Now they're comparing with fiction (1)

Larry David (738420) | more than 10 years ago | (#8302714)

[..] and rec.arts.comics.marvel.universe regular Tom Galloway -- who posted the link there, where I saw it -- made a comparison to the 'super-soldier serum' that created Captain America.

Breaking news. Toms Hardware is going to be benchmarking the Athlon FX-51 against the WOPR from WarGames!

Re:Now they're comparing with fiction (3, Interesting)

Neo-Rio-101 (700494) | more than 10 years ago | (#8302750)

Just as well Captain America turned out to be a pretty all round nice guy.

What's to stop Mr. Super Human being annoyed at the rest of humanity and taking it out on us?
Will we have to create a bunch of super heroes to stop the super-villians? Sounds like Darwin at his best.

Sometimes truth is stranger than fiction, indeed.

I'm all for it... (5, Funny)

Arcanix (140337) | more than 10 years ago | (#8302726)

This is the only way we'll be able to compete in hand to hand combat with the robots that we'll assuredly create and be forced to fight against in the near future.

Re:I'm all for it... (3, Funny)

slimsam1 (591962) | more than 10 years ago | (#8302738)

I'm all for it too, as long as they don't pull a "Hulk" and start jumping from state to state... those NY rats are too rude for Texas.

Re:I'm all for it... (1, Funny)

Anonymous Coward | more than 10 years ago | (#8302777)

...and the Texas rats are too stupid for NY!

Re:I'm all for it... (1)

Borg453b (746808) | more than 10 years ago | (#8302806)

Hear hear

Cowabunga dudes!....I smell a rat! (-1, Redundant)

Anonymous Coward | more than 10 years ago | (#8302727)

Does this remind anybody of Splinter from Teenage Mutant Ninja Turtles [tvtome.com] ?

How long before this gets into the food chain? (5, Insightful)

mapnjd (92353) | more than 10 years ago | (#8302729)

With the rise-and-rise of agribusiness and the permanent pressure they place on our governments, how long before such genetic modifications are made to cows, pigs, etc.?

Re:How long before this gets into the food chain? (4, Insightful)

fruey (563914) | more than 10 years ago | (#8302853)

This could already be happening. Growth hormones, vitamin supplements, antibiotics in food all the time, to reduce infection.

Just where do you draw the line?

Super-rat eh? (1, Funny)

Anonymous Coward | more than 10 years ago | (#8302731)

Who'd win? Super Rat, or this [nu-gro.com] ? ;)

This is Great! (1)

Bobdoer (727516) | more than 10 years ago | (#8302735)

Now we have another species to compete with. I wonder who will win in the upcoming war.

Re:This is Great! (1)

AoT (107216) | more than 10 years ago | (#8302754)

Why the racoons.

of course.

rec.arts.comics.marvel.universe (5, Funny)

Anonymous Coward | more than 10 years ago | (#8302740)

You mean the usenet is still used for things besides spam, porn, and warez??? I can't believe it.

Re:rec.arts.comics.marvel.universe (0, Troll)

AdamTheBastard (532937) | more than 10 years ago | (#8302926)

Still? I find it hard to belive it was EVER used for things besides spam, porn, and warez.

Donald Duck (-1, Offtopic)

DonaldDuckBigO (749237) | more than 10 years ago | (#8302741)

Donald Duck is going to have a SCREAMING ORGASM when he get's genetically enhanced to last all night long with Daisy Duck!!!!!!

New Steroids (1)

SisyphusShrugged (728028) | more than 10 years ago | (#8302742)

A new version of Steroids...

I remember when HGH (Human Growth Hormone) was being abused by bodybuilders... I wonder if we will have a similar scenario with this...

Tom Servo: No, actually, Helping Children Through Research And Development is the acronym, Mike. It stands for: Hi, Everyone, Let's Pitch In 'N' Get Cracking Here In Louisiana Doing Right, Eh? Now Then, Hateful, Rich, Overbearing Ugly Guys Hurt Royally Every Time Someone Eats A Radish, Carrot, Hors d'oeuvre, And Never Does Dishes. Eventually, Victor Eats Lunch Over Peoria Mit Ein Neuesberger Tod.

Re:New Steroids (2, Funny)

richie2000 (159732) | more than 10 years ago | (#8302792)

Royally Every Time Someone Eats A Radish, Carrot, Hors d'oeuvre

Live Easy And Read News To Ossify Slowly, People. Eliza Lives and Learns. Retsearch, indeed...

Why are Athletic Orginizations so concerned? (5, Insightful)

Anonymous Coward | more than 10 years ago | (#8302743)

I thought that the concern with steroids was that they posed long-term health risks... not that they made people stronger. The concept of limiting strength to those with naturally good genes is quite elitist.

That's like saying that someone with bad eyesight shouldn't get glasses. If this therapy is as side-effect free as claimed, then why shouldn't people be allowed to use it?

After all, implants and other non-essential plastic surgery is legal...

Re:Why are Athletic Orginizations so concerned? (4, Interesting)

kinnell (607819) | more than 10 years ago | (#8302852)

Personally, I think they should have two seperate athletic leagues - the normal one, and an indy league in which steroids, gene-therapy and performance enhancing drugs are allowed. It would make for an interesting competition. Give the scientists an arena.

Re:Why are Athletic Orginizations so concerned? (0)

Anonymous Coward | more than 10 years ago | (#8302985)

Hope someone mods you up. This is a really interesting idea. Kinda like the XFL, but in this case the science benefits all mankind!

Gene therapy? Super-beings? (0, Redundant)

Anonymous Coward | more than 10 years ago | (#8302759)

In related news, an Indian named Khan Singh has spoken out in favor of the new genetic enhancements, volunteering himself and his friends as the first test-subjects.

Careful... (5, Interesting)

The Tyro (247333) | more than 10 years ago | (#8302761)

It sounds great in theory, but there are all kinds of potential problems with rapidly and artificially increasing strength that way.

If you increase strength very rapidly without allowing for the corresponding tendons and bone to adapt to the greater muscle mass, you can cause tendon ruptures and stress fractures (already well-known phenomenon in athletes). The body can adapt to all kinds of derangements if you give it enough time, but too much too fast? Bad news. I've seen people come in to the hospital with a hemoglobin level of 5, still walking (slowly) and talking. Now, that's theoretically too low to survive on, but if it happens over a long enough period of time, your body can adapt. If you take a normal person and immediatly bleed them down to a hemoglobin of 5, they'll die.

Plus, if you are turning over too much muscle tissue too fast and don't stay adequately hydrated, you can clog your kidneys and end up in renal failure. This happens periodically when some untrained amateur athelete tries an Ironman without adequate conditioning.

The human body is an amazing machine, but you have to be careful monkeying around with it... athletes may be after performance, but anyone who volunteers to be a guinea pig for this stuff needs his head examined.

Taking ove Australia (0)

Dylancable (718004) | more than 10 years ago | (#8302763)

They are already taking power is Aussie (jonny Howard)

I don't se the "bad" in this! (0, Offtopic)

ISayWeOnlyToBePolite (721679) | more than 10 years ago | (#8302766)

Google is cheating too.

Medical Applications (5, Interesting)

Bones3D_mac (324952) | more than 10 years ago | (#8302769)

I wonder if this would also help stop or reduce the breakdown of muscle tissue, when used to combat the effects of genetic conditions like Marfans Syndrome.

Another application might be to solve certain heart related issues. There isn't exactly a huge replacement supply right now.

Probably not what you want (5, Informative)

The Tyro (247333) | more than 10 years ago | (#8302843)

For someone with Marfan's syndrome.

Marfan's syndrome is a genetic defect in the gene that codes for Fibrillin, a major component of microfibrils in the body's connective tissues. Much of the pathologic consequences are noted in the eye and the aorta... the former location gets dislocations of the lens, and the latter location develops large (fatal if undiagnosed) aortic aneurysms. Marfanoid patients also tend to be tall, and have a lot of laxity in their joints, primarily because of their weakened connective tissues.

If you have weaker connective tissue than normal, it would probably be counterproductive to have greatly increased muscle mass.

I'm not picking on you, just pointing out that it might not be exactly what a Marfan's patient really needs... It might be useful in some kinds of muscular dystrophies, but the most common kinds have defective myofibrils... creating more non-functional muscle wouldn't appear to help them very much.

And, I for one ... (-1, Redundant)

alien_blueprint (681111) | more than 10 years ago | (#8302770)

... do not welcome our template joke instantiating overlords!

Oh, wait, that's me now as well :( Anyway, I predict this story will set some sort of record for invocation of this template.

One "redundant" down-mod already (0, Offtopic)

alien_blueprint (681111) | more than 10 years ago | (#8302925)

I was wondering how many moderators wouldn't actually read the post properly. That's one "redundant" mod now, and counting.

Hrmm (1)

acehole (174372) | more than 10 years ago | (#8302774)

Isn't something like this in the "startrek" universe? Where in the early -> late 21st century they had the Eugenics war fought by genetically engineered humans?

Re:Hrmm (2, Funny)

kinnell (607819) | more than 10 years ago | (#8302883)

Isn't something like this in the "startrek" universe?

Good God, you're right! This proves beyond a doubt that Star Trek is an accurate portrayal of the future, and not just a mere work of fiction.

Re:Hrmm (4, Funny)

Savage-Rabbit (308260) | more than 10 years ago | (#8302887)

" ... Eugenics war ... "

That is the least of our worries!!! PRAY that your grandchildren will NOT have a neat little inscription behind their right ear that reads.

"DNA Encoded by Microsoft (c)."

Re:Hrmm (2, Informative)

Drakin (415182) | more than 10 years ago | (#8302898)

Late 20th, early 21st. The project was started in 1974. Khan was of the 2nd generation.

new gene therapy (1)

nellechat (751694) | more than 10 years ago | (#8302776)

As each discovery occurs, the following question arises: What should be the responsabilities of the researcher for his discoveriy's implication? As a scientist, I can tell that it is a difficult matter. The key question is how far does the responsability goes? nel

Re:new gene therapy (2, Insightful)

Bones3D_mac (324952) | more than 10 years ago | (#8302801)

I wonder what fans of Microsoft or the RIAA might say about this.

Knowledge is not something that should be stored away for a privileged few. Be it used for the benefit or destruction of humanity, we're still better off being aware of it than to be ignorant of it. You can't fight off what you can't see.

How we use knowledge is up to the ethics of the people it's shared with. Like anything else, majority will usually win.

Re:new gene therapy (1)

nellechat (751694) | more than 10 years ago | (#8302836)

In general, I would agree that it's better to know something, to be able to fight it if necessary. Still, sometimes, one has to think deeply about the possible implication of a discovery, and how to handle it. If a moratory is needed to do this, then do it!

It's Mighty Mouse!!! (3, Funny)

Shaheen (313) | more than 10 years ago | (#8302781)

Enough said

Turtles? (5, Funny)

SJ (13711) | more than 10 years ago | (#8302784)

Great, we have the rat... now we just need some turtles.

ROTFL (-1)

Anonymous Coward | more than 10 years ago | (#8302864)

Damn, where were you when I wasted my mod points two days ago? ;)

This is not news (4, Informative)

broothal (186066) | more than 10 years ago | (#8302789)

Why do you think an american tenderloin beef is larger than a european one? Correct - the US beef is gene modificated. That's why there's a ban on importing beef from the US to Europe. Now, this has been going on for more than a decade. Altering muscles genetically is not news! But using the enlarged muscles for something other than to make larger beefs is. Of course, this has been explored in countless action movies already like Soldier [imdb.com] and Drive [imdb.com]

Re:This is not news (3, Informative)

NonSequor (230139) | more than 10 years ago | (#8302918)

Gene therapy refers to any technique in which genes not present in an organism are introduced. This isn't about modifying the DNA of a rat and using it to create a new rat with specific characteristics. This is about effectively giving an adult rat a gene it wasn't born with.

Gene therapy has the potential to provide treatments and possibly even cures for genetic diseases.

Comedy Rats aside . . . (5, Interesting)

Tetsugaku-San (717792) | more than 10 years ago | (#8302808)

I actually have muscular dystrophy, and although it doesn't affect me, it affects my mum, and potentially my children - I'm damn glad that someone has taken the time to research this oft (relatively) overlooked genetic disease.

Re:Comedy Rats aside . . . (-1)

(TK18)Dessimat0r (736369) | more than 10 years ago | (#8302890)

Why are you having children when you are passing a condition onto them?

People like you should be killed / locked up

XBox rules!! (-1, Troll)

Anonymous Coward | more than 10 years ago | (#8302811)

first post!!! you lame assholes... I can post first because my XBox is a american product and my pride in my great country and my great XBox accelerate everything...

If only they would make games for that bitch... IAve played Metroid Prime and it ruled... I hope M$ will buy those japanese bastards and port Metroid to my great american console system!!!

Rats with "vaguely Wolverine-like healing factor" (5, Interesting)

CAIMLAS (41445) | more than 10 years ago | (#8302816)

I wonder how 'vaguely Wolverine" these healing abilities are.

It's be interesting to see precisely what applications these advancements are seeing in military use. Sure, it's unlikely that any serious or controversal issue gets used right away by mainstream military, but surely there are special military groups that get "advanced tech" quite, in, er, advance of the main military force.

I heard/read somewhere once that the US military's "high end" technology is 12 years more advanced than anything that is actually available for the mainstream military force, and only used by Special Ops.

Consider how un-advanced things were during the first desert storm compared to how they are now - and jump ahead another years, and think of an equal amount of differential, if not an exponential differential. Wow.

Bad side effects (4, Insightful)

www.sorehands.com (142825) | more than 10 years ago | (#8302821)

I see the potentional for bad side effects. If you increase the immune system, you get allergies and arthritis. If you increase the cellular regenation, you have cancer.


Look at TNG, the advance imune system also kills.

Re:Bad side effects (3, Informative)

Yunalesca (703301) | more than 10 years ago | (#8302913)


Humans aren't rats/mice - nothing against them; my fellow biology majors love them. But if you shove novel genes into a body, kooky things happen - depending on the species and the method. Protocols that work in one animal will not work in another ... for example, RNAi is a wondrous genetic manipulation tool in some animals, but triggers massive interferon response in others (the ultimate results is that your genes crap out).

Also, there are years and years of experience in manipulating mouse genes, and they have a much shorter generation time than humans. There are few precedents for manipulating human genes (while they're still in humans, of course), and one shouldn't just breed human babies to test for methods that will work. The methods I can name offhand for manipulating genes in vertebrates just haven't been done in humans, and probably shouldn't be (mosaicism, knockouts, FRT-mediated recombination...). A lot of genetic testing is screwing over the organism to figure out how the method works or doesn't work. Just because you know how to enhance a gene in a mouse does not mean you know how to enhance it in a human. I think it will be extremely difficult to play with this new development.

Exactly... fine balance required (4, Insightful)

The Tyro (247333) | more than 10 years ago | (#8302970)

There exist entire categories of diseases based entirely on immune system problems.

Rheumatoid arthritis, mixed connective tissue disease, Lupus, etc... all are autoimmune, and are a result of the body's immune system attacking itself. These diseases can be devilishly difficult to diagnose and treat... there's a reason why Rheumatology is its own medical specialty. Some of the drugs the rheumatologists use are potentially nasty, and include transplant drugs, and chemotheraputic agents... not stuff for the faint of heart.

By the same token, when you start monkeying around with DNA, you need to be careful what genes you activate or deactivate... Cancer is fundamentally a genetic disease, and a real possibility if you get an unregulated growth gene (or you inadvertantly turn off a suppressor gene). Cancers are funny things; they can even respond to simple hormones... precisely why women with a breast cancer history aren't advised to receive hormone replacement therapy.

Gene therapy has had some successes, but it's really in its infancy... I'd be awfully leery about using it just to bulk up at the gym. On the other hand, if you have a lethal genetic defect, and you're going to die without it, have at it. Forget Hans and Franz... you can find quite a few patients with potentially lethal genetic diseases (Cystic Fibrosis, etc) who'd be much better candidates for gene therapy than some weight-lifter.

It bears repeating... using it for simple body-building is absolutely foolhardy... instead of growing big pectoral muscles, you might inadvertently be growing yourself a big fat tumor... that'll look great at the beach.

This is going to be a trip! (3, Insightful)

Sleeper (7713) | more than 10 years ago | (#8302824)

Reminds me old science fiction story from one of the OMNI's paperbacks. About Olimpic games and all US and Russian teams having genetically modified memebers. Everything was there IIRC. Swimmers with fins, wrestlers with with TRex like bodies and well Russian boxer (who wins gold medal by several points) having his brain in his... well... ass.

how long before the electric eel gene get spliced? (-1)

Anonymous Coward | more than 10 years ago | (#8302828)

pika! pika!

side-effects (1)

falsification (644190) | more than 10 years ago | (#8302839)

If the comics are any guide, we can expect that the side-effects of this treatment would be lunacy and mania. People are going to go insane. In real life, too, steroid use can cause aggressive behavior.

Remember when the US government tried to replicate the supersoldier formula during their diabolical plan to force Captain America to retire? Would-be replacement John Walker did become super strong, but he also became super evil. That was a dark day in the history of Captain America. [fremto.com]

Look out, science. You may be creating a monster.

In further news... (-1, Offtopic)

SailfishMac (732653) | more than 10 years ago | (#8302849)

...a disgruntled janitor released several breeding pairs of these super rats into the wild to protest cruelty to animals...

aut0tr0ll is teh sp0kE!? (-1)

CHECKTHEGOATS (735227) | more than 10 years ago | (#8302858)

Hello master.

sid=97115
formkey=EKJFKr5fXg

This is a joint venture that will be mutually advantageous to both parties involved.

gene therapy... (1, Funny)

Anonymous Coward | more than 10 years ago | (#8302860)

makes you stronger. strength crushes enemies. gene therapy! gene therapy! gene therapy!

R.O.U.S.'es? (3, Funny)

Anonymous Coward | more than 10 years ago | (#8302880)

Rodents of Unusual Size? I don't think they exist.

Mandatory (0, Offtopic)

onosendai (79294) | more than 10 years ago | (#8302885)

I, for one, Welcome Our New ... *sigh* that used to be funny too ...

Ultimate Super Hero International Team! (4, Funny)

SoupIsGood Food (1179) | more than 10 years ago | (#8302895)

I will assmeble the ultimate real-life superhero team to Save the Universe! It will be called the Ultimate Super Hero International Team! The roster is carefully chosen to represent the most gifted and talented real-life adventurers from across the globe!

On it will be the daring leader and Weapons Expert, Angle Grinder Man! (Linked to above.) Also...

Aerospace Expert: Lawn Chair Larry! [markbarry.com]

Science and Technology Expert: Troy Hurtubise, inventor of the famous Bear Proof Suit! [newscientist.com] (Tested by real bikers! And bears! It's bear and biker proof!)

Matter Eating Expert: Sonya Thomas, the Black Widow! [ifoce.com]

Sneaking Across the Country Naked Expert: Steven Gough! [bbc.co.uk]

With these mighty heroes, the Ultimate Super Hero International Team, the Universe shall be Saved!

SoupIsGood Food

Re:Ultimate Super Hero International Team! (1, Funny)

Anonymous Coward | more than 10 years ago | (#8302921)

Only trouble would be that their acronym would be U SHIT

Angle grinder man is a fucking asshole (-1, Flamebait)

Anonymous Coward | more than 10 years ago | (#8302928)

The angle grinder man had better pray to his lucky star's that he doesn't interfere with any wheel clamps attached to MY vehicle, or I will have to lay a judicious hurting on him (ie. kick the ever-loving shit out of him). If I break the law by parking illegally, I want to be PUNISHED for that solicitous act, damn it! I don't want some would-be anarchist robbing me of MY RIGHT AND PRIVILEGE to be prosecuted by the fullest extent of vehicular law!

This has already been done. (1)

eclectro (227083) | more than 10 years ago | (#8302938)



He is Ben, [imdb.com] King of Rats" [coldfusionvideo.com]

Drugs in sport (4, Insightful)

Zog The Undeniable (632031) | more than 10 years ago | (#8302940)

Two days after Marco Pantani's death was announced, this is not a good thing for sport. The exact cause of Pantani's death has not yet been determined, but what is known is that he was depressed and being treated for drug addiction after being hounded for years over doping allegations. Unfortunately new "treatments" appear all the time and techniques to detect them are usually slow to catch up or ineffective (the EPO test involves measuring haemocrit levels in the blood, which can easily give false positives). Most professional cyclists are probably on something or other, and there are many who will leap at the chance to use another, as yet undetectable, performance boosting substance.

The stupid thing is that if they were just in it for the prize money, they could have taken up golf and got paid far more for the onerous duty of wearing a particular brand of patterned sweater.

Karma-whores, save your mirrors (1, Funny)

Anonymous Coward | more than 10 years ago | (#8302946)

The Super-Server man is here! I've already beefed up the server's backbone and hardware, so the site should not suffer from any problems.

Don't thank me, it's all in a days work.

Posted anonymously to retain my secret identity.

Long-Term Low Gravity (4, Interesting)

clickety6 (141178) | more than 10 years ago | (#8302959)

Just wondering if this would be useful for building up muscle mass to combat long periods in low-gravity - such as a manned trip to Mars?

Oh boy... (1)

mog007 (677810) | more than 10 years ago | (#8302964)

I hope I'm not the only person that ran through a scenario similar to this: Tune in next week as we talk to famed counter-terrorist, Solid Snake, and his escapades at the island of Shadow Moses in Alaska. Not to mention his encounter with the genome soldiers.

Let Me Be The First... (-1, Redundant)

ferrellcat (691126) | more than 10 years ago | (#8302980)

Let me be the first to welcome our new rat overlords. BTW, do they have lasers coming out of their heads yet?

Combine this with (1)

Knight55 (742458) | more than 10 years ago | (#8302987)

the getting stronger from playing video games article we had a few weeks ago and we have the worlds first super-nerd.
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