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Mice Created With Human Brain Cells

ScuttleMonkey posted more than 8 years ago | from the what-exactly-is-the-yuck-factor dept.

Science 339

pin_gween writes "Scientists have added 100,000 human brain cells to mice in an effort to create realistic models of disorders like Parkinson's Disease. Although mice are 97.5 percent genetically identical to humans and it sounds like a large number, 100,000 only represents 0.1% of the number of cells in mice brains. FTA: 'It's true that there is a huge amount of similarity, but the differences are huge,' Snyder said. 'You will never ever have a little human trapped inside a mouse or monkey's body. [...] Researchers are nevertheless beginning to bump up against what bioethicists call the "yuck factor." 'The worry is if you humanize them too much you cross certain boundaries,' said David Magnus, director of the Stanford Medical Center for Biomedical Ethics. 'But I don't think this research comes even close to that.'"

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339 comments

fp (0, Troll)

elvezZzZ (935966) | more than 8 years ago | (#14245513)

jews did 9/11 and TOOKIE REALLY DID HIS MURDERS. loooooooooooool. lameness filter aborted.

Re:fp (-1, Flamebait)

Anonymous Coward | more than 8 years ago | (#14245555)

Scientists have added 100,000 human brain cells to mice

That are 10,000 complete Apple-user brains!

Re:fp (-1, Troll)

Anonymous Coward | more than 8 years ago | (#14245568)

orly i also heard he raped the corpses afterwars with his big muscular penis. did you also know that he had a deal with a prison guard? i know it because it's a friend of mine. Tookie allowed him to stick his, you know, thing up his ass for some kfc original recipe the guard would smuggle in for him. But he never received the meal, LOLICONS, well at least he received something else, and a good lot of it too!

Re:fp (1, Funny)

TallMatthew (919136) | more than 8 years ago | (#14245646)

jews did 9/11 and TOOKIE REALLY DID HIS MURDERS. loooooooooooool. lameness filter aborted.

If only we could add 100,000 brain cells to you.

Re:fp (1)

PakProtector (115173) | more than 8 years ago | (#14245721)

jews did 9/11 and TOOKIE REALLY DID HIS MURDERS. loooooooooooool. lameness filter aborted.
If only we could add 100,000 brain cells to you.

Why waste those 100,000 brain cells in such an inhumane manner? I have the cure for stupidity right here.

A loaded revolver.

NARF! (5, Funny)

Noctopus (694337) | more than 8 years ago | (#14245516)

I for one welcome our new Pinky and the Brain [uni-duesseldorf.de] overlords [uni-duesseldorf.de] . NARF!

Re:NARF! (0)

Anonymous Coward | more than 8 years ago | (#14245524)

"You will never ever have a little human trapped inside a mouse" or flies?

"Help me! Help me!"

Re:NARF! (-1, Offtopic)

Lisandro (799651) | more than 8 years ago | (#14245527)

On a completely unrelated (and offtopic, sorry) note - does any of my fellow /.tters know if there are plans for a Pinky & the Brain DVD set? I'm dying for it.

Re:NARF! (2, Informative)

mahju (160244) | more than 8 years ago | (#14245590)

through my extensive research [google.co.uk]
I came up with this [tvshowsondvd.com]
We've got great news for you, then! Industry sources, speaking on condition of anonymity, have let us know that Warner Home Video has both of these animated series on their radar screen for a possible mid-2006 DVD release! Look for a multi-disc set for each show, with around two dozen episodes per box.

Re:NARF! (0)

Anonymous Coward | more than 8 years ago | (#14245614)

I love you man!

Are you thinking what I'm thinking? (0)

Anonymous Coward | more than 8 years ago | (#14245566)

Yes, because we have the same brains.

Re:NARF! (-1)

Anonymous Coward | more than 8 years ago | (#14245632)

Rofl, thanks for the good start to the day.

42 (5, Funny)

Anonymous Coward | more than 8 years ago | (#14245518)

The mice were furious.

Re:42 (2, Funny)

strider44 (650833) | more than 8 years ago | (#14245535)

The average mouse IQ lowered by about 5 points.

Re:42 (1)

AndroidCat (229562) | more than 8 years ago | (#14245609)

And you know this because you had mice running tests in mazes? Suddenly running down the wrong way, eating the wrong bit of cheese... Such subtlety, one has to admire it.

Re:42 (-1)

Anonymous Coward | more than 8 years ago | (#14245771)

You forgot "unexpectedly dropping dead of myxomatosis". Shame on you.

what are we going to do tonight brain... (0, Redundant)

know1 (854868) | more than 8 years ago | (#14245519)

...same thing we do every night pinky....get experimented on barberously!

Re:what are we going to do tonight brain... (2, Funny)

ozmanjusri (601766) | more than 8 years ago | (#14245567)

get experimented on barberously!

They gave you a bad haircut? The bastards!

Re:what are we going to do tonight brain... (1, Funny)

PakProtector (115173) | more than 8 years ago | (#14245636)

get experimented on barberously!
They gave you a bad haircut? The bastards!

Seriously! They shaved their tails bald!

97.5% genetically identical (2, Funny)

rhade (709207) | more than 8 years ago | (#14245525)

so is all this 97.5% like generic organ, dna stuff? i dont see the similarities between humans and mice

Re:97.5% genetically identical (5, Insightful)

kfg (145172) | more than 8 years ago | (#14245581)

so is all this 97.5% like generic organ, dna stuff?

You're about 50% banana.

i dont see the similarities between humans and mice

You obviously haven't even looked at a banana very closely, let alone a mouse. About the only difference a lifeform from the proverbial Mars would see between a human and a mouse would be scale. We are virtually identical to mice in every detail but stature.

If you want learn human anatomy, disect a chicken, and a chicken isn't even a mammal.

KFG

Re:97.5% genetically identical (1)

el americano (799629) | more than 8 years ago | (#14245612)

If you want learn human anatomy, disect a chicken...

Comments like this explain why KFC kicked KFG's ass in fast food poultry.

Re:97.5% genetically identical - ah yes, but (0, Flamebait)

OneSmartFellow (716217) | more than 8 years ago | (#14245623)

We are virtually identical to mice in every detail but stature.

God is in the detail

Re:97.5% genetically identical - ah yes, but (2, Insightful)

OneSmartFellow (716217) | more than 8 years ago | (#14245630)

In that same vein:

A brick house is virtually identical to a pile of sand in every detail but stature.

Re:97.5% genetically identical - ah yes, but (3, Interesting)

kfg (145172) | more than 8 years ago | (#14245686)

Compare a brick house to a brick factory building.

Mice and men are made of the same bricks, assembled in the same manner, ending with much the same results, which is why they can use mice for medical research in the first place. Above poster has it right, God is in the details, but the details are really very, very tiny. Sometimes those tiny differences are critical, but it doesn't make them any less tiny.

I'm sorry if it insults your sense of humanity to be compared to a mouse, but I don't exactly see the point of gaining your "stature" by denigrating mice either.

You're "smarter" than a mouse, of course, but being "smarter" isn't even of any particular value if you don't act smarter, and the mouse can do something you likely can't. . .

Take care of itself.

KFG

Re:97.5% genetically identical (3, Insightful)

grimJester (890090) | more than 8 years ago | (#14245615)

They are mammals. Most of their bodies work the same as ours although they are on different scales. They have muscle tissue, brain tissue, eyes, a skeleton etc. that work the same way ours do. They are similar enough to us that many/most of the same drugs that work on us work on them. Apart from size and shape there are no major differences.

Re:97.5% genetically identical (2, Funny)

thelonestranger (915343) | more than 8 years ago | (#14245709)

They are similar enough to us that many/most of the same drugs that work on us work on them. It's true..I came home last night to find that some mice had gotten into my stash and were sat around giggling and eating nachos.

Re:97.5% genetically identical (3, Interesting)

oudzeeman (684485) | more than 8 years ago | (#14245701)

dna that encodes protien synthesis is largely the same, although obviously arranged differently in the chromosomes. that 97.5 match figure is spread all through the genome - a gene that encodes the same thing in mice and man could be located at entirely different positions.

The company I work for http://www.jax.org/ [jax.org] maintains over 2,000 straings of laboratory mice for sale to other research institutions (we do genetics research and are designated a national cancer center, the 69 million dollar a year mouse business all started by selling surplus mice to other researchers, now it's a large part of the company and there has been discussion about spinning it off as a for-profit subsidiary. Right now, since all the surplus funds from the mouse business go directly towards supporting the research, we enjoy a tax-free status). We have models for diabetes, glaucoma, aids, certain cancers, adult onset obesity, etc. In experiments that involve drug testing, the only real difference (after you factor in mass differences) between mice and humans is how fast the mice metabolize the drugs.

well i think (3, Insightful)

know1 (854868) | more than 8 years ago | (#14245528)

" 'The worry is if you humanize them too much you cross certain boundaries,' said David Magnus, director of the Stanford Medical Center for Biomedical Ethics. 'But I don't think this research comes even close to that.'"

it's the thin end of the wedge. maybe this wasn't human enough...and nor will the next infinitessimally small step...but one day it will be too far and we won't have even realised

Re:well i think (2, Interesting)

ozmanjusri (601766) | more than 8 years ago | (#14245585)

but one day it will be too far and we won't have even realised

Then why will it have been too far?

Re:well i think (0)

Gherald (682277) | more than 8 years ago | (#14245789)

> > but one day it will be too far and we won't have even realised

> Then why will it have been too far?


You have to understand the conservative mindset: it will be bad because at that point in time we will not have the exact same moral reaction as we would today.

Almost any moral change is anathema to conservatives. In the USA, for example, about the only such change they have conceded is that minorities and women should have roughly equal rights to white males. Particularly ludicrous is that some are still against contraceptives....

Re:well i think (1)

KiloByte (825081) | more than 8 years ago | (#14245587)

Yeah -- we ("we" as the researchers and (an infinitessimally small contribution) those who give them moral support) already crossed an important boundary.

Before, this research was protested only by few fringe tree huggers. Now you need to count in a whole bunch of religious fundies, and they are those who can block the funding.

Re:well i think (1)

HillaryWBush (882804) | more than 8 years ago | (#14245634)

You are the one who is a religious fundamentalist, if you have so much faith that science should be funded. Where do YOU draw the line? Can we engineer monkeys to contain a gene to knife each other and serve themselves with banana sauce? Well, maybe in a few years.

Re:well i think (0)

Anonymous Coward | more than 8 years ago | (#14245591)

You're right!

Lets stop all scientific research because perhaps, at some point in the future, further research leading on from that might not be ethical.

Re:well i think (-1, Troll)

FungosBauux (929423) | more than 8 years ago | (#14245593)

"'The worry is if you humanize them too much you cross certain boundaries,' said David Magnus, director of the Stanford Medical Center for Biomedical Ethics. 'But I don't think this research comes even close to that.'"

Yes, certain boundaries. F#%$# you. Using other animals to experiences already is "certain boundaries".

At least, they wont be too "human" and so, they will not destroy and kill other species only for fun. This right, we cannot give to any other animal, because we can easily lost our "superiority".

Re:well i think (4, Interesting)

PakProtector (115173) | more than 8 years ago | (#14245649)

"'The worry is if you humanize them too much you cross certain boundaries,' said David Magnus, director of the Stanford Medical Center for Biomedical Ethics. 'But I don't think this research comes even close to that.'"

Yes, certain boundaries. F#%$# you. Using other animals to experiences already is "certain boundaries".

At least, they wont be too "human" and so, they will not destroy and kill other species only for fun. This right, we cannot give to any other animal, because we can easily lost our "superiority".

Woah, there! Easy now, fellah! We've already lost that one to Chimps, at the very least, who have been seen to actively seek out and kill Chimps that don't belong to their own group, going so far as, when finding a lone 'other,' to head back, round up a posse, and then go 'curb stomp' their 'ass.' Chimps will also kill babies of any female they meet that they have not had sex with. Hence Chimp promiscuity.

And dolphins also commit gang-rape.

We humans aren't so special after all.

Re:well i think (1)

DrSkwid (118965) | more than 8 years ago | (#14245655)

David Magnus, director of the Stanford Medical Center for Biomedical Ethics.

an oxymoron of the highest order

Ethics, yeah, I'm all for them, in other people!

Re:well i think (3, Insightful)

rooftop (848580) | more than 8 years ago | (#14245633)

And maybe with the next small step they cure Parkinson's disease. Maybe it's my secular mind, but i find killing and disecting millions of mice far worse than "upsetting god" by growing an ear on a mouse or putting in some human cells.

If the mice are happy and not in constant pain or anything, i don't really see what's wrong with it. Evolution creates new species all the time.

poor humans (-1, Flamebait)

cycledance (812080) | more than 8 years ago | (#14245529)

and we can do that to the mice because...?

Re:poor humans (0)

Anonymous Coward | more than 8 years ago | (#14245539)

Well, I dunno, guv, where were you when we started caging the poor bastards? Or confusing them with Apple peripherals?

Re:poor humans (2, Funny)

Walt Dismal (534799) | more than 8 years ago | (#14245550)

Outsourcing programming becomes even cheaper once you have mice with human brain cells. Pay attention, Bill.

The myth of the poor mouse (3, Insightful)

SimianOverlord (727643) | more than 8 years ago | (#14245772)

Mice and Rats in research are supposed to be pitied, by the usual pathetic ways that humans impart everything around them with the feelings or emotions which we possess. Actually, you should look at some facts.

FACT: Mice in the wild live about a year, in the most stressful, difficult and inhumane conditions you wouldn't like to imagine. Should they be unfortunate to gain access to one of the animal rights protestors habitat, middle class suburbia, the self same protestor, full of indignation at experimental killing, will of course call in someone to rid them of their little problem, or condemn them to freeze to death in wooded areas with humane capture traps. In the lab, mus musculus live on average about 2 years in controlled, warm conditions with regular feeding and exercise.

FACT: Rats in the wild live about 2 years max, again in stressful, disease ridden cramped conditions. In the lab, Rats can survive double that, again in nicely ordered, well controlled and comfortable conditions.

So don't bring up that ignorant rubbish about how animal experiments somehow harm rats and mice: unlike Joe Public taking potshots at rats and mice in his backyard, everything WE do is sanctioned, pored over and refined each and every step of the way to minimise suffering. Hell, our animals are no use for experimentation if they're unhappy or agitated: they get difficult to handle. We go to see them and handle them a couple of weeks before expts even start to get them used to our presence, smell, voices etc.

Rats and mice are far better treated in our labs than in the wild or in your homes, and they are also better treated than the conveyor belt of cattle fattened and slaughtered for your own diet. I get angered by the hypocrisy of people opposed to experimentation while conveniently overlooking the animal suffering inherent in large scale production of meat in all the developed world, with cattle stunned with bolt guns wandering into saws. It's so much easier to criticise someone else than look at your won behaviour, isn't it?

WTF? (5, Funny)

Tune (17738) | more than 8 years ago | (#14245531)

I thought mice - being pan dimensional beings - were far more advanced than humans (ranked 3, just after dolphins).
This is like modding an xbox 360/ps3/whatever with a Z80 - why whould you want to do that?

Re:WTF? (1)

PakProtector (115173) | more than 8 years ago | (#14245657)

I thought mice - being pan dimensional beings - were far more advanced than humans (ranked 3, just after dolphins). This is like modding an xbox 360/ps3/whatever with a Z80 - why whould you want to do that?

Because somewhere, everytime you do it, a Systems Engineer dies inside.

That, or it makes God cry. I forget exactly. Oh, well. Back to masturbating. Gotta get rid of those kittens somehow.

Re:WTF? (1)

Guppy06 (410832) | more than 8 years ago | (#14245722)

"This is like modding an xbox 360/ps3/whatever with a Z80 - why whould you want to do that?"

Because the Sega Master System kicked ass!

Re:WTF? (1)

pato101 (851725) | more than 8 years ago | (#14245763)

This is like modding an xbox 360/ps3/whatever with a Z80 - why whould you want to do that?
To play Manic Miner, obviously.

Read the summary (1)

ion_ (176174) | more than 8 years ago | (#14245775)

I thought mice - being pan dimensional beings - were far more advanced than humans (ranked 3, just after dolphins). This is like modding an xbox 360/ps3/whatever with a Z80 - why whould you want to do that?

Well, duh, the summary answers your question:

"Scientists have added 100,000 human brain cells to mice in an effort to create realistic models of disorders like Parkinson's Disease."

If you want to research human diseases in such advanced beings as mice, you need to put stuff from humans to the mice.

I for one welcome our new Brainy Mice Overlords (3, Funny)

digitaldc (879047) | more than 8 years ago | (#14245534)

'The worry is if you humanize them too much you cross certain boundaries,'

Translation: The worry is that the mice will sue for cruel & unusual punishment and civil rights violations if humanized too much.

Re:I for one welcome our new Brainy Mice Overlords (1)

afaik_ianal (918433) | more than 8 years ago | (#14245570)

I don't think you're going to get too many lawer mice out of this. To do that, you need to remove some of the original brain material, and substitute in some shark brain cells.

Re:I for one welcome our new Brainy Mice Overlords (0)

PakProtector (115173) | more than 8 years ago | (#14245705)

I don't think you're going to get too many lawer mice out of this. To do that, you need to remove some of the original brain material, and substitute in some shark brain cells.

Run! The Munchkin Rules Lawyers cometh!

Re:I for one welcome our new Brainy Mice Overlords (1)

madaxe42 (690151) | more than 8 years ago | (#14245661)

Whether the mice become sentient or not, you can be sure some lawyer will file a class action suit on their behalf.

and the first 2 mice created said... (3, Funny)

mahju (160244) | more than 8 years ago | (#14245541)

"Why Brain, what are we gonna to do tomorrow night?"

"Guess... "

"Oh yeah, try to take over the world, right... "

I for one welcome... (5, Funny)

ocelotbob (173602) | more than 8 years ago | (#14245551)

Yay, human-brained mice. This means that once they escape and start rampaging, scientists will have no choice but to create a race of catpeople to counter them. Of course, this will lead to revolts creating a need for dogpeople, but for a short time, I shall have my catboy! Vengance shall be mine!

Re:I for one welcome... (1)

laejoh (648921) | more than 8 years ago | (#14245569)

Yay, human-brained mice. This means that once they escape and start rampaging, scientists will have no choice but to create a race of catpeople to counter them. Of course, this will lead to revolts creating a need for dogpeople, but for a short time, I shall have my catboy! Vengance shall be mine!

Why? We have zombies for that! Let them chase the mice.

Mmmmh.... Brains!!!!

Re:I for one welcome... (1)

PakProtector (115173) | more than 8 years ago | (#14245667)

I'm gonna go out on a limb here, and assume that you're female, since you have a need for a cat'boy.' So, uh, I have these adorable ears left over from my Inu Yasha costume...

Um. Yeah. That's all I really had to say.

Re:I for one welcome... (1)

ettlz (639203) | more than 8 years ago | (#14245676)

Of course, this will lead to revolts creating a need for dogpeople...

"I'm a mog — half man, half dog. I'm my own best friend!"

Re:I for one welcome... (0)

Anonymous Coward | more than 8 years ago | (#14245782)

> I'm my own best friend!

What a coincidence, I've been my own lover for years.

Re:I for one welcome... (1)

AndroidCat (229562) | more than 8 years ago | (#14245707)

Got to have cat girly-girls too!
Hid the Bell with a blot she did.
But she fell in love with a hominid.
Oh, where is the which of the what she did?
- The Ballad of Lost C'mell

TOOKIE WILLIAMS: MURDERER, NEGRO, PHP PROGRAMMER (-1, Troll)

Anonymous Coward | more than 8 years ago | (#14245571)

PHP: CREATED BY FAG JEWS, LOVED BY DIRTY NEGEROS

ANY TRUE HUMAN BEING (READ: WHITE PERSON) WOULD NEVER WRITE SOFTWARE IN SUCH A NIGGARDLY LANGUAGE! ANYONE WHO CREATES SOFTWARE IN SAID LANGUAGE IS A RACE TRAITOR! GET RID OF YOUR NIGGARDNESS! DROP THE KIKESPEAK! ABOLISH THIS ANTI-HUMAN FAGGOT COMPUTER LANGUAGE AT ALL COSTS!


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Re:TOOKIE WILLIAMS: MURDERER, NEGRO, PHP PROGRAMME (0)

HaydnH (877214) | more than 8 years ago | (#14245639)

I see we've found out which human donated the brain cells for this study!!

That seems about right... (-1, Redundant)

Fahrvergnuugen (700293) | more than 8 years ago | (#14245578)

100,000 only represents 0.1% of the number of cells in mice brains

Sounds like my coworkers...

The "yuck factor" (5, Funny)

TripMaster Monkey (862126) | more than 8 years ago | (#14245583)


Researchers are nevertheless beginning to bump up against what bioethicists call the "yuck factor."
Everyone wants to save Hitler's brain...
but when you put it in the body of a Great White Shark,
suddenly, you've gone too far.
Professor Farnsworth

Re:The "yuck factor" (1)

midicase (902333) | more than 8 years ago | (#14245652)

"...yuck factor."

What, no wikipedia entry for this highly technical term?

As I sip from my Pinky and the Brain coffee cup.

Re:The "yuck factor" (2, Funny)

PakProtector (115173) | more than 8 years ago | (#14245693)

FRY:Hey, Wait a minute! Is this another experiment that crosses a line that man was not meant to cross?

PROFESSOR: Holds Index finger and thumb almost together, shrugging

The conscious neuron? (5, Interesting)

jtangen (861406) | more than 8 years ago | (#14245588)

Remind me what's so unique about human neurons that cause people to fear that mice will somehow become conscious, thinking organisms?

Re:The conscious neuron? (2, Funny)

penguinoid (724646) | more than 8 years ago | (#14245703)

The problem is that the Flying Spaghetti Monster might give the mice a soul if we give them too many human brain cells.

% brain cells (-1, Redundant)

Anonymous Coward | more than 8 years ago | (#14245589)

100,000 only represents 0.1% of the number of cells in mice brains.

Unfortunately, I know a number of humans to whom this would be a fourfold increase in brain volume.
Yes, some of them are politicians.

Keeping a tally... (5, Insightful)

Metasquares (555685) | more than 8 years ago | (#14245606)

So far we have super-strong, long-lived, regenerating mice with human brain cells. We're getting pretty close to "the mice of NIMH".

brain simulation? (4, Interesting)

Anonymous Coward | more than 8 years ago | (#14245613)

If 100.000 brain cells is 0.1% then a mouse has 100.000.000 brain cells. How many bytes does it take to describe a brain cell? How many connections are there from a single brain cell to other brain cells? Say it takes 4 bytes to address the connections. Then 10 connections per cell make 4GByte in total. Who is going to write the software to simulate a mouse?

Re:brain simulation? (2, Informative)

wanax (46819) | more than 8 years ago | (#14245742)

Modelling 'real' neurons in detail is generally done with ~10k compartmental models, which are generally described by something like:
http://neuron.duke.edu/cells/ [duke.edu]
and modelled in something like:
http://www.neuron.yale.edu/neuron/ [yale.edu]

Even using vastly simplified neurons, like integrate & fire types, for example: http://www.nsi.edu/users/izhikevich/publications/s pikes.htm [nsi.edu]
you still have many vastly different types of spiking behaviors.

You then still have to deal with the fact that neurons 'generally' connect to about ~10k others, (actual range something like 10-100k). And that's before you get to details like what neurons are where, with what densities, that long range connections in mammalian brains are generally not very well understood, etc. etc. etc.

The brain is a lot more complicated than you think. We're still many many years away from modeling a mouse brain, at a purely neuronal level. I mean, there still isn't a definitive model of the Aplysia, neuron count ~10k...

Re:brain simulation? (5, Interesting)

penguinoid (724646) | more than 8 years ago | (#14245759)

Neurons have several thousand connections, not "about 10". Furthermore, these connections are analog (have a range of strengths), say 1 byte to address the strenghts. Given about 100,000,000 brain cells, you would need almost 30 bits per connection as well, but call it 3 bytes. At 1000 connections, you need 4 kb per neuron, or 400 Gb of memory for 1 rat brain. Barely doable, but the processor power to handle all of that will not be easy to find...

Pity... (0, Troll)

marcushnk (90744) | more than 8 years ago | (#14245624)

'You will never ever have a little human trapped inside a mouse or monkey's body.

What a pity... we could do with a decent contender for the positions currently held by Bush/Blair/Howard.

news from old friends (2, Funny)

illuminatedwax (537131) | more than 8 years ago | (#14245631)

Good to hear that NIMH is still up and running after that last scandal. They do good work.

Wow...30 minute hangtime (1)

StressGuy (472374) | more than 8 years ago | (#14245675)

Ya kinda knew Pinky and the Brain would be instantaneous, I was waiting for the first NIMH reference. 30 minutes though.....long time

That's disgusting!! (3, Funny)

LaughingCoder (914424) | more than 8 years ago | (#14245659)

Scientists have added 100,000 human brain cells to mice

Now I don't even want to touch my mouse! I guess it's back to the command line for me.

Splinterscats... (0)

Anonymous Coward | more than 8 years ago | (#14245665)

Add a little magic and we can create splinterscats - remember Morrowindl?

"Boundaries" (4, Insightful)

base_chakra (230686) | more than 8 years ago | (#14245668)

The worry is if you humanize them too much you cross certain boundaries

How about if we cross a different barrier and drop the anthropocentric bullshit.

why dumb them down (1, Insightful)

Anonymous Coward | more than 8 years ago | (#14245673)

They are already a higher species. They created the Earth. Why dumb them down with human brain cells -- they have more than enough of their highly-compact molecular memory.

No human inside mice (1, Funny)

Dekortage (697532) | more than 8 years ago | (#14245684)

From the article: "It's true that there is a huge amount of similarity, but the difference are huge," Snyder said. "You will never ever have a little human trapped inside a mouse or monkey's body."

Just remembering people I've worked with, I think we already have mice and monkeys trapped inside humans.

What's with the interest in super mice lately (0)

Anonymous Coward | more than 8 years ago | (#14245689)

Not too long ago there was an article about making fearless mice. Now there is an interest in humanizing mice. Hmmmm.
Is the goal to have intelligent mice not afraid of anything? What's with the interest in super mice lately???

"The worry is if you humanize them too much... (0, Troll)

PhotoBoy (684898) | more than 8 years ago | (#14245696)

...you cross certain boundaries."

Personally I don't really like experimentation on animals, so you can try to dehumanise the animals being experimented as much as you want, it won't change my objections.

I'm frightened now. (1)

meringuoid (568297) | more than 8 years ago | (#14245717)

According to recent /. coverage, mice are now

- fearless
- immortal
- regenerating
- mighty

and now it seems
- they have human brain cells

We could be in trouble here. I believe the word 'kamehame-ha' would form an appropriate response to what we're creating...

Mouse Brain Library (2, Interesting)

tomalpha (746163) | more than 8 years ago | (#14245726)

Anybody reckon they can tell the difference between a human brain and a mouse brain? Check out the Mouse Brain Library [mbl.org] and the Human Brain Library [harvard.edu] . There are a couple of obvious difference in shape, but the individual structures are remarkably similar.

so far... (5, Funny)

Gravis Zero (934156) | more than 8 years ago | (#14245738)

so just for the record, we can make super strong fearless immortal mice that can sing, regenerate body parts, sniff out landmines, and have partial human brains. scientists don't mod their computer cases, they mod their mice!

Genetic Similarity (1)

ajs318 (655362) | more than 8 years ago | (#14245750)

Some genetic similarity is overstated. If you took two samples of DNA that were different in every way they possibly could be different, they would still have 50% in common.

OTOH, some genetic similarity is understated. The human genetic code consists of 23 chromosome pairs, in which a single chromosome differs between the sexes. Therefore, at the lowest biological level, men and women have 45 similarities for every one difference.

President's worst fear. (2, Funny)

unknownideal (881232) | more than 8 years ago | (#14245754)

"But the brain poses an additional level of concern because some envision nightmare scenarios in which a human mind might be trapped in an animal head."

Someone kindly explain to President Bush why this is impossible. And don't laugh. He doesn't like being laughed at.

reminds me of an old saying about paper.. (1)

necromcr (836137) | more than 8 years ago | (#14245767)

It's said paper can take anything (i always remember of toilet paper when I remember that..) but lately it looks like mice are taking over (and the parallel: yuck factor).

God help us..

Mouse? (1, Funny)

dreadpiratemark (450962) | more than 8 years ago | (#14245777)

So typical of Logitech to toss out a new mouse with *great* new features (human like response!) two weeks after I buy their latest dual-laser bluetooth model. Anyone know the DPI on this new mouse?

Religious Consequences (0)

Anonymous Coward | more than 8 years ago | (#14245781)

A basic thought among most people in the world is that humans are greater, in some form or another, than all other entities. A basic thought in many religions is that humans have souls and these souls goto heaven when we die. If we make a mouse "human" enough, where it behaves, and thinks like a human, does that mouse now have a soul? Imagine if the mouse is capable of interacting with humans, where the only real difference is that the "souless" mouse is still physically a mouse, but with the metnalcapabilities of a "soulful" human. Will this mouse goto heaven? The religious consequences could be so drastic that they could crumble many belief systems around the world. I, for one, would love to see how human we can make any animal. We must push these limits. Many go through life wondering why? why are we here? where do we go afterwards? Unfortunately, certain people come up with ridiculously outrageous theories but believed by many who cannot think for themselves and are desparate for a "path" in life.
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