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Designer Mice Made to Order

ScuttleMonkey posted more than 8 years ago | from the time-to-start-a-mouse-farm dept.

382

blackbearnh writes "CNN is reporting about the world of designer mice. No, not the kind you click, the kind that scamper around and eat cheese. An effort is underway to produce mice with each of the 20-25,000 individual mouse genes "knocked out", which could lead to novel new treatments for humans. It turns out that after fully sequencing the mouse genome, the little fellas are almost identical to humans. From the article: 'A mouse with arthritis runs close to $200; two pairs of epileptic mice can cost 10 times that. You want three blind mice? That'll run you about $250. And for your own custom mouse, with the genetic modification of your choosing, expect to pay as much as $100,000.'"

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would you? (5, Funny)

dotpavan (829804) | more than 8 years ago | (#14870055)

A mouse with arthritis runs close to $200; two pairs of epileptic mice can cost 10 times that. You want three blind mice? That'll run you about $250. And for your own custom mouse, with the genetic modification of your choosing, expect to pay as much as $100,000.'"

Oh, and Would you like to have fries with it?

Re:would you? (1)

lju (944654) | more than 8 years ago | (#14870083)

How about a mouse that tastes like chicken?

Re:would you? (1)

dotpavan (829804) | more than 8 years ago | (#14870105)

thanks, but I am a vegetarian.

Re:would you? (1)

LiquidCoooled (634315) | more than 8 years ago | (#14870145)

Got a special on carrot flavoured mice this week.
They glow in the dark as well.

Re:would you? (1)

dotpavan (829804) | more than 8 years ago | (#14870203)

I would wait for the technology to improve and try mice-flavored-carrots.

Re:would you? (0)

Anonymous Coward | more than 8 years ago | (#14870099)

Or maybe a little PETA.

Somwhere.... (0)

Anonymous Coward | more than 8 years ago | (#14870147)

A patient Richard Gere is waiting for this technology to be passed on to hampsters.

Re:would you? (5, Funny)

Lev13than (581686) | more than 8 years ago | (#14870211)

To: Jackson Laboratory, Bar Harbor, ME
Re: Genetically modified mice

Dear Sir,

I understand that you are in the business of breeding custom-designed mice. I find this quite fascinating, as I require custom animals for my experiments. Do you, by chance, have any specimens which are flexible, clawless and agoraphobic?

Regards,
R. Gere

Re:would you? (1)

jonnythan (79727) | more than 8 years ago | (#14870458)

I don't get it.

Re:would you? (2, Funny)

Anonymous Coward | more than 8 years ago | (#14870484)

I understand that you are in the business of breeding custom-designed mice. I find this quite fascinating, as I require custom animals for my experiments. Do you, by chance, have any specimens which are flexible, clawless and agoraphobic?

Just order a dozen of the epileptic ones and get some nail clippers.

Frist post (-1, Offtopic)

Anonymous Coward | more than 8 years ago | (#14870069)

Meow!

You've got to be kidding me? (-1, Troll)

zoloto (586738) | more than 8 years ago | (#14870074)

Why the hell would you want to do that to the little creatures? Permanently disabling them for your "oh so cute" factor? I'm not one of those tree hugging animal rights people but this just screams animal abuse in a way. And no, I didn't RTFA very much.

Re:You've got to be kidding me? (4, Funny)

jcostantino (585892) | more than 8 years ago | (#14870095)

It's probably for scientific research... I seriously doubt that someone would buy mutant mice for fun.. well, unless they had frickin' laser pointers on their heads.

Re:You've got to be kidding me? (0)

Anonymous Coward | more than 8 years ago | (#14870122)

Ever heard of scientific research?

Re:You've got to be kidding me? (2, Insightful)

I confirm I'm not a (720413) | more than 8 years ago | (#14870153)

And no, I didn't RTFA very much.

You know, it was the "oh so cute" comment that gave it away. Somehow I suspect that anyone paying for a mouse with diabetes is probably more concerned about diabetes than "cute".

Jeez - I am one of those tree hugging animal rights people but your post just screams "pratt" to me. Either that or <tinfoil-hat>agent-provocateur for pharma-com</tinfoil-hat>

.

You insensitive clod! (0)

Anonymous Coward | more than 8 years ago | (#14870216)

There is nothing cuter than a diabetic mouse.

I'm saving up and getting me two.

Re:You've got to be kidding me? (1, Funny)

Anonymous Coward | more than 8 years ago | (#14870307)

You know, it was the "oh so cute" comment that gave it away. Somehow I suspect that anyone paying for a mouse with diabetes is probably more concerned about diabetes than "cute".

Although obese mice are pretty darn cute. Pic. [wisc.edu] More. [google.com]

Re:You've got to be kidding me? (1)

Miraba (846588) | more than 8 years ago | (#14870188)

At first you sounded like a knee-jerk animal rights activist. Then when I got to your last line, it became apparent that you're a trolling moron.

They're for pharmaceutical research. Or did you think that biologists don't have moral problems creating and testing drugs on humans without the benefit of animal models?

Re:You've got to be kidding me? (1)

Frumious Wombat (845680) | more than 8 years ago | (#14870296)

No, for cute I expect them to bred up to the size of Beagles. Of course, at that point I've recreated the woodchuck, so I'd be better off trying to domesticate an existing rodent, rather than getting one custom designed.

Laser Mouse? (5, Funny)

compuguy84 (886540) | more than 8 years ago | (#14870091)

...Priceless...

Mouse human? (1)

gcnaddict (841664) | more than 8 years ago | (#14870172)

I mean, if they're that close to human beings in terms of genetics, couldnt we just turn them into uber-smart rats? (mice with massive brains, etc.) 100,000 is a bargain for a mouse with psychic powerz

Re:Mouse human? (2, Interesting)

MyLongNickName (822545) | more than 8 years ago | (#14870252)

Yup. Cause if turning a mouse into a super intelligent being were possible with a few smippets of gene code, evolution would not have produced it over millions of years.

Often, the "good" gene combinations that produce a desirable trait have negative reprocusions that far outway the positive ones.

I will attribute him [wikimedia.org] to blind luck on the part of the researcher.

Re:Mouse human? (1)

ScriptedReplay (908196) | more than 8 years ago | (#14870457)

I will attribute him [wikimedia.org] to blind luck on the part of the researcher.

Indeed, I always thought Brain to be the price paid for creating Pinky.

Hmmm... that's an idea... (3, Funny)

thanq (321486) | more than 8 years ago | (#14870096)

How much for a pair of fast, reliable, self-sustaining mice that can keep my cats exercising and entertained each day so I don't have to?

Re:Hmmm... that's an idea... (1, Funny)

superdan2k (135614) | more than 8 years ago | (#14870159)

Probably not a cost effective idea. Really, once the cats start approaching some semblence of "shape", the mice will need to be replaced on a daily basis. Furthermore, the cats will need more exercise to work off the mouse calories.

Re:Hmmm... that's an idea... (2, Funny)

LiquidCoooled (634315) | more than 8 years ago | (#14870193)

1) Goto petshop and purchase a mating pair.

2) Release into basement.

3) ???

4) Profit (well, not losing money getting some super mouse built to order)!

special mice ... really special (1, Interesting)

Simonetta (207550) | more than 8 years ago | (#14870255)

How much for a pair of reproducing "mice" that are a big as beavers, can chew through the aluminium siding, rip arms and legs off with their paws, and can run 100 yards in 10 seconds?

What is stopping anyone from making these ecological monsters? Is there some kind of scientific oversight group? Or a set of defined ethical and/or ecological guidelines? Like in Pierre Ouilette's sci-fi novel about plant-animal genetic hybrids that was published in 1993 and whose name excapes me.

Re:special mice ... really special (0)

Anonymous Coward | more than 8 years ago | (#14870374)

Well other than the ripping arms and legs off and perhaps te sprint requirement what you specified already exists. It is called....a beaver.

Re:special mice ... really special (2, Funny)

Dr Caleb (121505) | more than 8 years ago | (#14870387)

"can chew through the aluminium siding, rip arms and legs off with their paws, and can run 100 yards in 10 seconds?"

With that kind of mouse, you'll have to replace your cat more often. Not to mention walls, fences and your neighbours' Volvo.

Re:special mice ... really special (2, Interesting)

soft_guy (534437) | more than 8 years ago | (#14870408)

How much for a pair of reproducing "mice" that are a big as beavers, can chew through the aluminium siding, rip arms and legs off with their paws, and can run 100 yards in 10 seconds?

What is stopping anyone from making these ecological monsters?


Probably the fact that you are limited to genes that can be found in the mouse population.

Re:special mice ... really special (3, Interesting)

Wyatt Earp (1029) | more than 8 years ago | (#14870468)

True, but Rodents have the widest range in size of any mammal order. The African Pygmy Mouse is only 6 cm in length and 7 grams in weight. On the other hand, the Capybara can weigh up to 45 kg (100 pounds) and the extinct Phoberomys pattersoni is believed to have weighed 700 kg.

http://en.wikipedia.org/wiki/Rodent [wikipedia.org]

So I bet with some tweaking you could have a beaver sized mouse.

Re:special mice ... really special (1)

glorpy (527947) | more than 8 years ago | (#14870444)

Nothing... except little things called biomechanics and kinesthesiology. Animals tend to scale poorly across orders of magnitude. Besides, a lot of those traits listed require multiple genomes and modified mitochondrial DNA.

Re:Hmmm... that's an idea... (0)

Anonymous Coward | more than 8 years ago | (#14870290)

"...a pair of fast, reliable, self-sustaining mice that can keep my cats exercising..."

Um, a dog?

Re:Hmmm... that's an idea... (1, Insightful)

Anonymous Coward | more than 8 years ago | (#14870349)

Uh.. you don't need mice for that. For that you will need a dog.

Uhmmm.... (5, Interesting)

mark-t (151149) | more than 8 years ago | (#14870097)

Does not the deliberate creation of a living creature to have a specific disability of some sort seem in some way cruel or inhumane? Or is it just me?

Re:Uhmmm.... (1)

Spy der Mann (805235) | more than 8 years ago | (#14870121)

Does not the deliberate creation of a living creature to have a specific disability of some sort seem in some way cruel or inhumane? Or is it just me?

I assume these mice are for lab tests.

Re:Uhmmm.... (1)

eviloverlordx (99809) | more than 8 years ago | (#14870221)

I assume these mice are for lab tests.

Or they're the next generation of stealth fighter pilots.

Re:Uhmmm.... (0)

Anonymous Coward | more than 8 years ago | (#14870438)

ahh the old "but it's for science" routine.

Re:Uhmmm.... (1, Insightful)

Anonymous Coward | more than 8 years ago | (#14870166)

its just you. humans have been doing it forever in some form or another so its not inhumane. as for it being cruel...well..life is cruel, sucks to be a lab mouse.

Re:Uhmmm.... (1)

Rude Turnip (49495) | more than 8 years ago | (#14870287)

I don't think the mice care; they just accept who they are. A lesson learned perhaps?

Re:Uhmmm.... (3, Insightful)

iamlucky13 (795185) | more than 8 years ago | (#14870289)

Genetic engineering does raise some ethical questions, but it's not like they're raising these mice to laugh at them. "Hehe, these mice are blind. Let's put them in the carpenter's kitchen to see if his wife cuts off their tails!"

Is it playing God or using our natural faculties for the betterment of mankind? Where do you draw the line? Is it ok to make glow-in-the-dark mice, but not mice with 6 legs? What about glow-in-the-dark mice versus glow-in-the-dark E-choli (I did the latter back in high school)? Or glow-in-the-dark people?

I hate mulling over these questions because it's so hard to set a standard to judge them by, but they have to be asked or it gets out of control.

Isn't it more cruel or inhumane.. (5, Insightful)

drgonzo59 (747139) | more than 8 years ago | (#14870313)

Not to conduct such research on mice and let hundreds of thousands of people die of heart disease, diabetes and cancer. Mice in-vivo and in-vitro tissue models are invalueble to heart, diabetes and cancer research. They are mammals, they breed fast and a lot is already know about them.

I work in a heart research lab where we cut the hearts out of the mice and attach them to a working heart machine and pump a blood subsitute through it. Then we test various drugs and load conditions on it. The question is would you like to volunteer so that we test the drugs first on you, or your older family members, instead of the mice so as to spare their lives? Or would you rather be assured that in hundreds of mamalian tests the durgs performed as they are supposed to and the effects are clear and reproducible.

We abide by the rules and anaesthesize the mice carefully, we don't torture them and try to do the best we can to minimize their suffering. Personally I wish we didn't have to do this, I don't like to kill things -- animals or people, but in this case it is worth it to save many human lives.

Re:Isn't it more cruel or inhumane.. (0)

Anonymous Coward | more than 8 years ago | (#14870359)

ermmm.... no

Re:Isn't it more cruel or inhumane.. (1, Insightful)

Anonymous Coward | more than 8 years ago | (#14870446)

and what's the leading cause of heart disease in this country that scientists have to 'fix'?

I hear you whisper it. Say it loudly. MEAT EATING AND LACK OF EXERCISE.

It's a racket I tell ya. Crappy diets create heart disease giving doctors and scientist's jobs while mice suffer.

I hate this CNN article. It glorifies the company. Meh.

Re:Isn't it more cruel or inhumane.. (0)

Anonymous Coward | more than 8 years ago | (#14870483)

how about we stop keeping people alive when its time to go...

exercise and healthy diets.

cant wait till 50 years time and we cant sustain our older generations.

Re:Uhmmm.... (2, Funny)

Saven Marek (739395) | more than 8 years ago | (#14870317)

Apparently it's not a problem, as one of the differences with mice and people is they don't feel pain, so they can't notice if there's anything wrong. Also, they don't have social systems like we do so there's no stigmas attached to their disabilities so if they're OK with it as mice I don't see what the problem is?

Re:Uhmmm.... (1)

P3NIS_CLEAVER (860022) | more than 8 years ago | (#14870346)

Well if you care so much for mouse feelings donate your body to science and let them experiment on you instead. Think of the mice!

Re:Uhmmm.... (1)

DARKFORCE123 (525408) | more than 8 years ago | (#14870363)

Happens all the time when women are pregnant who are abusing drugs or smoking. Its well know what disabilities a baby could have due to excesses of drugs or alcohol.

Re:Uhmmm.... (1)

Verminator (559609) | more than 8 years ago | (#14870381)

It's not just you.

I think we as a species are racking up all sorts of bad karma.

Re:Uhmmm.... (3, Funny)

TheNarrator (200498) | more than 8 years ago | (#14870426)

The best reason of all to experiment on mice though is to get back at them for the spreading (via fleas) the 13th century Black Death plague that led to over a 3rd of Europe's population dying! Just think of the irony! They tried to eliminate us by spreading disease and we are using them for medical research!

Obj HHGttG Reference (3, Funny)

blackbearnh (637683) | more than 8 years ago | (#14870098)

Oh, those clever mice, letting their genes be manipulated, mysteriously developing arthritis, glowing in the dark.

Re:Obj HHGttG Reference (1)

wildsurf (535389) | more than 8 years ago | (#14870419)

How much are they charging for Frankie and Benjy Mouse?

(£42, no doubt.)

Mouse (1)

Blue Mandelbrot (951902) | more than 8 years ago | (#14870103)

How about a Logitech mouse, with a laser and a scroll wheel? I like to shop around for the best price.

Leopard Skin (3, Funny)

Jozer99 (693146) | more than 8 years ago | (#14870109)

How about a mouse in a leopard skin print to match my decour?

Re:Leopard Skin (0)

Anonymous Coward | more than 8 years ago | (#14870241)

Here it is, this is one of the companies mentioned in the article.

http://www.deltagen.com/deltaone/blast.html [deltagen.com]

No more concern about endangered species? (4, Interesting)

team99parody (880782) | more than 8 years ago | (#14870110)

We're quickly entering an age where we'll be creating species's faster than we can kill them off; so we shouldn't get all worried when we kill them off. Last bald eagle dies -- just order a bald flying mouse.

I'm partially kidding; but partially serious too. If today's california condor isn't well suited in the modern environment; wouldn't it be better to grow better ones more able to survive - rather than forcing the unfortunate few remaining ones to suffer in an environment no longer well suited to them?

Re:No more concern about endangered species? (2, Funny)

Golias (176380) | more than 8 years ago | (#14870197)

If today's california condor isn't well suited in the modern environment; wouldn't it be better to grow better ones more able to survive?

No, you fool! If you do that, NOTHING will stop them! We'd be doooooomed!!!

Re:No more concern about endangered species? (0)

Anonymous Coward | more than 8 years ago | (#14870249)

Yeah. Let's install freakin' laser beams on their heads.

Re:No more concern about endangered species? (3, Insightful)

rainbowfyre (175300) | more than 8 years ago | (#14870260)

If today's california condor isn't well suited in the modern environment; wouldn't it be better to grow better ones more able to survive - rather than forcing the unfortunate few remaining ones to suffer in an environment no longer well suited to them?

Yeah, sure. Until we make just one mistake. Then, we have a condor that is very well suited to a suburban environment -- it just eats stray pets!

I do not trust any human, no more how brilliant, to modify life. We don't know how the ecosystem works, and the law of unintended consequences will bite us in the ass.

Cassia

Re:No more concern about endangered species? (4, Insightful)

mblase (200735) | more than 8 years ago | (#14870280)

If today's california condor isn't well suited in the modern environment; wouldn't it be better to grow better ones more able to survive - rather than forcing the unfortunate few remaining ones to suffer in an environment no longer well suited to them?

Well, part of the cause of the California condor's decline is humans shooting them for sport. So I'll assume you don't include that in your definition of "environment no longer well suited to them."

Part of the problem is that we cannot, yet, grow better animals to survive. This article is talking about crippling mice in specific ways for medical science; eugenics is exactly the opposite technology.

Another issue is the question of species survival. Since we can't gene-sequence an animal complete for later resurrection, especially when that animal's population is under 200 like the California condor's.

The ultimate goal is to preserve species diversity in the wild as much as possible. Human expansion across the planet has had a far more devastating effect on species diversity in every possible environment than natural selection could ever achieve. Too few species and you have a kind of monoculture, filled with a small number of species excellently adapted to parasitizing human society but lousy at doing much of anything else.

Re:No more concern about endangered species? (2, Insightful)

compuguy84 (886540) | more than 8 years ago | (#14870286)

I agreed with your comment for a second before realizing that creating 'better suited' condors, for instance, is really avoiding the issue. Are they endangered because they're not fit for the environment anymore, or because of catastrophic changes in that environment caused by human interference? It's sort of like putting more air in a tire day after day because it keeps going flat. Wouldn't it be better to patch the hole? We should try to stop crapping on the enviroment before wasting research $$ on creating super-condors that use smog as a fuel source.

Sounds unlikely (4, Insightful)

No Such Agency (136681) | more than 8 years ago | (#14870330)

The amount of "genetic design" (to borrow the phrase from Blade Runner) required to make condors or any other species "better adapted to a new habitat" is simply not possible with today's knowledge of biology. Every aspect of the condor's physiology - lung function, flight muscles, temperature tolerance and body insulation, sight - is the result of millenia of "tweaking" via natural selection. We can currently barely get a single gene to express predictably in a new species, and that requires a lot of work and money to do. "Re-adapting" the condor is something a Victorian pigeon breeder would have much better luck at than a modern molecular biotechnologist - but he'd still need decades to do it, one generation at a time.

"Knockout mice" are altered to reduce or eliminate a single gene's function, in a simple binary fashion. They are an extremely reductionist technology, used to answer quite reductionist questions of how molecular pathways behave. They are, despite their cost and sophistication (and usefulness), a very crude development.

Let's not mistake the genes for the creature (0)

Anonymous Coward | more than 8 years ago | (#14870371)

Reasons why trying to deal with endangered species by just cloning some more is not an entirely good idea, include
  1. Genetic diversity. Great, so you've got 34 condors now instead of 0! Except, oops, they all have the exact same genes. Look forward to a brief period of what evolutionary biologists call "Founder Syndrome" and the rest of the world calls "inbreeding".
  2. Pack sustainability. It may not be enough to just make 2 or 20 condors. It may be that without a certain critical lower bound of population, social, mating, etc behaviors will fail to kick in and the species will just die out again a week after you reintroduced it.
  3. Social behavior. Many species cannot effectively or cannot be raised in captivity. You need existing members of the species to do things like teach it social behaviors. You can't do that if you've just killed off all the "in the wild" animals of that type and all you've got is born-in-captivity clones.
I mean, it's maybe an idea worth looking into. But don't expect it to solve problems or anything.

Blind mice for 250$??? (1)

Anonymous Coward | more than 8 years ago | (#14870118)

If I wan't some blind mice, I can just poke eyes right?

at the end of article.. (-1, Troll)

dotpavan (829804) | more than 8 years ago | (#14870127)

it says: "These mice are not going to tell us everything, and sometimes they tell us nothing. But as a starting point," Austin said, "mice play a central role."

This is really sick! How soon could we see similar genetic market for humans?

Re:at the end of article.. (1)

MrTeter (925391) | more than 8 years ago | (#14870212)

Based on the movies I've seen, they should be coming out around the year 2020 along with the flying car and complete meals in pill form.

Profit! (5, Funny)

cowboy76Spain (815442) | more than 8 years ago | (#14870129)

1. Catch three normal mice somewhere
2. !!!!!!
3. Sell three blind mice for $250
4. Profit!

Re:Profit! (1)

SpinJaunt (847897) | more than 8 years ago | (#14870244)

Come on now, you should know that step two is sleep:

1. Catch three normal mice somewhere
2. Sleep!!!!!!
3. Sell three blind mice for $250
4. Profit!

Re:Profit! (1)

Mahou (873114) | more than 8 years ago | (#14870487)

you must be a horrible sleepwalker

Wistful thinking (4, Funny)

jaymzter (452402) | more than 8 years ago | (#14870133)

Work with me here.. A mouse with laser beams for eyes!! And he flies, and with super strength shall lay the capitals of the world to waste! I shall call him.. MIGHTY MOUSE!!

Unless you pay me the sum of One Million Dollars!!

Re:Wistful thinking (2, Informative)

Bazzalisk (869812) | more than 8 years ago | (#14870328)

Nah, you can't call him that, Apple have a trademark.

How much.... (3, Funny)

mblase (200735) | more than 8 years ago | (#14870138)

...for a superintelligent white mouse [amazon.com] ? I want to be able to create my own three-dimensional sculpture with a living element before those things go out of style.

Re:How much.... (1)

frank_adrian314159 (469671) | more than 8 years ago | (#14870331)

... superintelligent white mouse?

Ithink you meant this one [blackwolf-images.com] .

This is news? Maybe for some of you... (4, Insightful)

Miraba (846588) | more than 8 years ago | (#14870149)

When I saw this as a preview, I wondered why this could be considered news. Anyone who works in biotech is familiar with specialty mice and the companies that make and breed them.

Then I realized that given the makeup of /. (lots of "hard science" geeks), this could be considered new information to a number of people here. But still, news? I can only assume that when an old topic hits CNN, it suddenly becomes news again.

Re:This is news? Maybe for some of you... (0)

Anonymous Coward | more than 8 years ago | (#14870261)

Did you see this one [slashdot.org] ? Software that backtranslates protein sequence to DNA! And it determines restriction sites!

The people here are a bunch of scientific illiterates who just want a pretext to bitch about patents and hold forth on how uneducated everyone else is. Honestly, when science news here isn't flat out wrong I consider it a win.

Re: Designer Mice Made to Order (5, Funny)

JeanBaptiste (537955) | more than 8 years ago | (#14870167)

Can you make them with the cheese already inside?

That would really save me a lot of trouble...

I prefer Mozzerella.

Thanks in advance.

Intelligent Design (5, Funny)

RedHatLinux (453603) | more than 8 years ago | (#14870190)

Does this count as intelligent design?

Re:Intelligent Design (1)

vhmauery (588437) | more than 8 years ago | (#14870429)

I don't think it counts as intelligent design, but it certainly shows that Douglas Adams wasn't far from the truth when he said that mice were the most intelligent beings in the universe.

Re:Intelligent Design 666 (1)

WillAffleckUW (858324) | more than 8 years ago | (#14870436)

Does this count as intelligent design?

If you consider grad students intelligent ... why yes.

.

.

.

please note that's a joke told by grad students, not of grad students

I know I'm not the only one by far... (-1, Redundant)

AirRaven (843900) | more than 8 years ago | (#14870276)

...But I find this absolutely disgusting.

I'm not some knee-jerking animal rights nut. I'm just a human being. The thought of deliberately breeding living creatures so that they'll become arthritic sickens me.

What gives us the right? How can we do these things to living creatures with minds of their own?

Put yourself in their position. I know that's laying it on a bit thick, but it's at this point that most people start turning away from what anyone says if it's against this kind of thing. They dismiss it as a "silly idea" without actually doing it.

Are scientific advances really worth the equivalent of torture? It depends upon your point of view, I know, but from a moral standpoint, is there any way of justifying this?

(Slashdot being Slashdot, I look forwards to being modded down for this.)

Re:I know I'm not the only one by far... (0)

Anonymous Coward | more than 8 years ago | (#14870334)

How can we raise animals just to kill and eat them? How can we raise animals just for leather? The world is a messed up place. But you can't really point fingers at any generation because humans have been doing crap on the same level as this as long as we have exsisted. I mean think about it we used apes for radiation tests to see how it would effect humans. We sent chimps into space as a test and if they didn't come back alive we would have just done it again and again until they came back alive.

Re:I know I'm not the only one by far... (1)

P3NIS_CLEAVER (860022) | more than 8 years ago | (#14870388)

Well if you care so much for mouse feelings donate your body to science and let them experiment on you instead. Think of the mice!
Be sure to donate all your granola stores to the starving children.

Re:I know I'm not the only one by far... (1)

WillAffleckUW (858324) | more than 8 years ago | (#14870411)

What gives us the right? How can we do these things to living creatures with minds of their own?

You do realize that they eat dogs, which are much smarter, in about half of the world, don't you?

Or even pigs - they're smarter.

Or goats.

Don't even get me started on force-feeding duck livers to make foie gras (fat liver ...).

Re:I know I'm not the only one by far... (2, Insightful)

Miraba (846588) | more than 8 years ago | (#14870422)

Had your polio vaccinations? Happy that you'll never get smallpox? Thank animal research.

Consider it a necessary evil.

Re:I know I'm not the only one by far... (1, Insightful)

Anonymous Coward | more than 8 years ago | (#14870472)

Just out of curiousity, do you take immune system impairing drugs? Because your body regularily produces white blood cells that kill other living things.

I'm not bloodthirsty and definitely am against random injury and killing to animals, but for the purposes of improving our knowledge of medicine and life in general I am all for animal testing. As long as it's as humane as possible, I value human life over animal life. Much the same way those animals value their lives over mine and yours.

Re:I know I'm not the only one by far... (1)

scapermoya (769847) | more than 8 years ago | (#14870480)

What gives us the right? I think that getting a step closer to finding a cure for (pick one: arthritis, AIDS, cancer, blindness, cerebral palsy, epilepsy, cystic fibrosis, etc etc etc etc) in people is worth dedicated scientific experimentation on any number of animals. Are you suggesting that we halt all medical experiments on animals? That is animal nut-esque. I do some work occasionally with pigs that will eventually lead to much lower incidences of heart attacks for certain people. The pigs we use have to die in order for us to carry out our experiments. Im no fan of senseless murder and inducing pain in animals, but if you know anyone with a debilitating illness, you will understand why we do these experiments.

Re:I know I'm not the only one by far... (-1, Troll)

soft_guy (534437) | more than 8 years ago | (#14870486)

I saw films in college of dogs bred to have narcolepsy. They were hillarious. I would love to have a narcoleptic dog.

bpitch (-1, Offtopic)

Anonymous Coward | more than 8 years ago | (#14870284)

Pet snake (1)

Recovering Hater (833107) | more than 8 years ago | (#14870288)

So now I can order some really cool altered mice for my pet snake! No more plain old food anymore. Designer gourmet altered mice coming right up. I wonder if he would like them spots or what? No more ghetto albino mice.

Designer mice? (2, Funny)

njchick (611256) | more than 8 years ago | (#14870304)

I want a Christian Dior mouse, with pink floral ornament and letters "CD" on the belly.

The gay gene (0)

blaksaga (720779) | more than 8 years ago | (#14870323)

Ooooh, send me a little furry with the gay gene and dress him up in leather. I'll call him tiddliwinks.

Re:The gay gene (0)

Anonymous Coward | more than 8 years ago | (#14870391)

You mean lemmiwinks right? =P

Re:The gay gene (1)

garrett714 (841216) | more than 8 years ago | (#14870410)

I'll call him tiddliwinks.

I think you meant Lemmiwinks.

"Lemmiwinks, you must find a passage to the small intestine!"

LOL, South Park is so twisted.

Shaggy mice (0)

Anonymous Coward | more than 8 years ago | (#14870325)

Maybe a bit offtopic, but a friend of mine that was a huge reptile buff always had feeder mice around. After about 4 generations of inbreeding, he'd get mice with really long hair - like little guinea pigs.

I for one..... (0, Redundant)

compuguy84 (886540) | more than 8 years ago | (#14870332)

...welcome our disabled rodent overlords.

Dream mouse (0)

Anonymous Coward | more than 8 years ago | (#14870345)

How soon until I can order one of these [playmouse.com] ?

$100,000? Worth it! (1)

brian0918 (638904) | more than 8 years ago | (#14870360)

$100,000 is a small price to pay for finally kicking some script kiddie ass in Counter-Strike...

Laboratory Mice, whose Genes have been Spliced (1)

TigerPlish (174064) | more than 8 years ago | (#14870386)

...can I get one hell-bent on world domination, and one with the IQ of a North Dakotan Winter?

I just dunno what I'd call 'em...... NARRRF!

My faves are the Nude Glowing Mice (4, Interesting)

WillAffleckUW (858324) | more than 8 years ago | (#14870393)

A lot of recent research that's interesting to me includes designing siRNA and miRNA "virus" packages to target cancers and other tumors in mice specifically bred to have increased, decreased, or normal (control) reactions to certain diseases.

It's fun to watch the tumors glow red, green, blue, yellow, or a mixture of two or more.

The best part is if you squish the mice a bit but not too much, held flat to a transparent plate, you can see the glow without killing off the mice.

Sadly, this doesn't work with humans, they're too dense (can't see thru them easily), or we'd be further along with methods of locating and killing or at least targetting for excision (surgery) the tumor cells, especially when they have designed receptor tags (an offshoot of HIV research, actually).

Now if we could just design glow-in-the-dark instant tattoos for humans, that would change color if you started to have certain diseases (say HIV or TB or whatever), now that would be super cool.

I'd get mine as a standard-light invisible one, with a green serpeant that had red fangs if I had whatever disease, and maybe a blue afro if I was coming down with something common ...

Apple's Mighty Mice (0, Offtopic)

Aqua OS X (458522) | more than 8 years ago | (#14870409)

or for $50 bucks you could get one of Apple's designer mice.... but it will probably suck. It'll either have one button or it won't be able to register a right click 10% of the time. It may also include uncomfortable squeeze buttons.
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