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World's Most Used Painkiller Being Linked To Heart Attack Risk

Diggester (2492316) writes | about a year and a half ago

Medicine 2

Diggester (2492316) writes "Diclofenac, according to studies, is the most used and most popular painkiller in the world. It may not be as popular as other non-steroidal anti-inflammatory drug (NSAID) in the United States, its popularity is boosted in, at least, 15 countries as it continues to outsell naproxen, ibuprofen, and other NSAIDs.
Studies also suggest that diclofenac may increase the chance of heart attack in a person by 40 percent. If his annual heart attack risk is 1 in 1,000, it will be increased to 1.4. The figures may be perceived as "insubstantial" but for people with higher heart attack risk, it's different."

Link to Original Source

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That's not an original source. (1)

queazocotal (915608) | about a year and a half ago | (#42894803)

http://www.ncbi.nlm.nih.gov/pubmed/23382889 [nih.gov] is an original source.
The 40% figure of increased heart attacks is for patients over 30, who have already had a heart attack.
If they are treated with diclofenac - they are 40% more likley to die.
However.
This study says nothing on risk for those not at risk of heart attacks.

Re:That's not an original source. (1)

queazocotal (915608) | about a year and a half ago | (#42894881)

http://www.ncbi.nlm.nih.gov/pubmed/20530789 [nih.gov] is another paper which addresses 'healthy' people.
Diclofenac, Ibuprofen amongst others were both found to increase heart attack risk in healthy people by around 1.6*, Naproxone was not.

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