Beta

Slashdot: News for Nerds

×

Welcome to the Slashdot Beta site -- learn more here. Use the link in the footer or click here to return to the Classic version of Slashdot.

Thank you!

Before you choose to head back to the Classic look of the site, we'd appreciate it if you share your thoughts on the Beta; your feedback is what drives our ongoing development.

Beta is different and we value you taking the time to try it out. Please take a look at the changes we've made in Beta and  learn more about it. Thanks for reading, and for making the site better!

The Role of Mitochondrial DNA in Aging and Cancer

pnotequalsnp (1077279) writes | more than 6 years ago

Sci-Fi 0

pnotequalsnp (1077279) writes "Doug Wallace, PHD UC Irvine, gave a very interesting talk on the role of Mitochondrial DNA (mtDNA) entitled "Human Origins, Aging, Cancer & Degenerative Disease".

One of the interesting conclusions is that aging is correlated to body temperature (or exercise) and overeating. mtDNA produces ATP and heat. In warm blooded humans, typically their mtDNA produces more heat for the body by burning calories. On the other hand, cold blooded humans produce less heat and more ATP to use as energy for the body. Basically, keeping your electron transfer chain oxidized in your mtDNA (by exercising or converting calories to heat) will reduce cancer risk (free radicals produced). If you have a tightly coupled mtDNA (produce less heat and more ATP) and you overeat (meaning more calories), then you will reduce the electron transfer chain within your mtDNA, creating more free radicals, resulting in apotosis (cell suicide) and you will age faster.

In short, calorie restricition will increase lifespan and reduce cancer risk, especially in cold blooded humans.

Click here for a video of the talk"

cancel ×

0 comments

Check for New Comments
Slashdot Account

Need an Account?

Forgot your password?

Don't worry, we never post anything without your permission.

Submission Text Formatting Tips

We support a small subset of HTML, namely these tags:

  • b
  • i
  • p
  • br
  • a
  • ol
  • ul
  • li
  • dl
  • dt
  • dd
  • em
  • strong
  • tt
  • blockquote
  • div
  • quote
  • ecode

"ecode" can be used for code snippets, for example:

<ecode>    while(1) { do_something(); } </ecode>
Create a Slashdot Account

Loading...