martyros writes "Researchers at the Baylor College of Medicine are performing clinical trials of a cocaine vaccine which teaches the immune system to attack cocaine, preventing it from giving a high. The vaccine is made by attaching inactivated cocaine molecules to the outside of inactivated cholera protiens. When the immune system attacks the cholera protiens, it also "learns" the cocaine molecules as well. The result is that the immune system "recognizes the potent naked drug when it's ingested. The antibodies bind to the cocaine and prevent it from reaching the brain, where it normally would generate the highs that are so addictive.""