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New study finds the flu virus 'paralyzes' immune s

mmmscience (1450939) writes | more than 5 years ago

Medicine 1

mmmscience (1450939) writes " A study coming out of Children's Hospital of Philadelphia, Pennsylvania, has found that the influenza virus manages to dysregulate the immune system, allowing other infections to thrive in the body. This discovery, coming at an opportune time as the world battles the new H1N1 flu outbreak, may be the first step in understanding why the flu can cause such high mortality rates in normally healthy individuals."
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Very Preliminary Data (1)

gpronger (1142181) | more than 5 years ago | (#27832485)

The article in the ,Journal of Leukocyte Biology [] raises a critical point, but is based upon some very limited patient data. For instance they classify the patients studied into "Severe", "Moderate" and RSV (not respiratory syncytial virus) and controls, with each group composed of 10, 5, 6, and 24 individuals respectfully. Also, the ages were relatively broad; for severe the average was 3.4 years (0.2-12.6 years), for moderate the average was 6.3 years (3 months-12 years), and the RVS group was 2.2 years (22 days-4 years), while the controls were 6.9 years (0.5-19 years).

My point being is that the potential indication of the research needs to be picked up and validated with a more comprehensive study.
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