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Experimental Drug Compound Found To Reverse Effects of Alzheimer's In Mice

MisterSquid Re:That's more than reversing the effect (105 comments)

They have no idea what these things are doing. I especially wouldn't be taking some drug whose apparent mechanism is covalently binding to my brain.

I can't help but think of Flowers for Algernon

about two weeks ago
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Senior RIKEN Scientist Involved In Stem Cell Scandal Commits Suicide

MisterSquid Re:Case closed (127 comments)

Also, Greenland has quite possibly the coolest flag in the world, next to Nepal. Also, Iceland is rather icy, especially in the middle. Like greenland.

According to that Wikipedia list (as of now), Greenland has the highest suicide rate while Nepal has the lowest.

Coincidence? I think NOT.

about two weeks ago
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Windows XP Falls Below 25% Market Share, Windows 8 Drops Slightly

MisterSquid Re:Who has the market share? (336 comments)

I think the opposite (or "opposite") of "skeuomorphic" would be "abstract" or "non-representational" because non-skeuomorphic would not seek to mimic something that physically exists.

At least one Quora user suggests "abstraction" as the antonym of "skeuomorphism" ("abstractionism" would be the better equivalent, as "abstraction" is a noun form and is more rightly compared to "skeuomorph").

In that same Quora thread, another user outlines three domains of design, "Semiotic", "Semantic", and "Pragmatic". From what I know of poststructural linguistics, I would say "semantic" is a good near fit for the why and what of "abstraction" but neither "semiotic" nor (especially) "pragmatic" have obvious equivalents in UI design and aesthetics.

Looks like a whole new field of UI design is being forged as a result of changes to empirical UI forms! AWESOME.

about two weeks ago
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Greenpeace: Amazon Fire Burns More Coal and Gas Than It Should

MisterSquid Re: Clever editors. (288 comments)

[. . .]A far better way to reduce CO2 emissions would be to buy condoms for Nigerians. People that are never born emit far less CO2 than those that are. Long term problems require long term solutions.

Well that's quite a foolish (and probably racist) thing to say. According to wikipedia, Nigeria puts out less CO2 than 42 other countries, while China, the US, the EU, India, and Russia top the list in that order. I'm willing to bet that Nigerians also probably aren't particularly high-carbon emissions per capita compared to people in my country, the United States.

But this is all a bit much because you probably don't really want to control the population of the biggest CO2 emitters, do you? You're more likely interested in using any convenient and sloppy excuse to call for population control for nations whose citizens you don't particularly care for.

You wouldn't happen to be ethincally Chinese by any chance, would you, ShanghaiBill? Because if so, according to your own logic and wikipedia, you should hand out condoms to yourself.

about three weeks ago
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Siberian Discovery Suggests Almost All Dinosaurs Were Feathered

MisterSquid Re:Whelp. (139 comments)

I wonder how much resistance a theory like this gets just because feathered dinosaurs wouldn't look nearly as cool as the ones we see pictured today?

For me, the resistance comes when I look at the large reptiles of today which are descended from dinosaurs.They don't have feathers.

about three weeks ago
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Can the Multiverse Be Tested Scientifically?

MisterSquid Re:Not really (147 comments)

I'm confused here, can't you keep reading one particle and observing different spins based on when you observed it?

Short answer: NO.

Longer answer: measuring state collapses the waveform and every subsequent measurement will be the same.

Disclaimer: I am not a physicist nor do I pretend to be a physicist. These facts established, I am not your physicist, either. If you check back tomorrow, I still will not be a/your physicist.

about a month ago
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Can the Multiverse Be Tested Scientifically?

MisterSquid Re:Not really (147 comments)

"This is an easy one. Entangled particles operate using the same physics as wormholes. If one of the entangled pair is accelerated to relativistic velocities, say in a particle accelerator, they will not exist in the same relative timeframe. (SNIP)" That's a misunderstanding of entanglement. There is not per see communication between the particle. When you have an entangled particle there is not one "communicating" the other that it is getting observed. What happens is that *both* particle form a single system with the specific property that when the spin of one particle is measured , the other particle has the anti spin state. Using all sort of relativistic trick on one particle will not do anything whatsoever because there is no communication to the other particle therefor frame of reference do nothing whatsoever. [. . .]

I'm mostly an untutored observer in the domain of Quantum Mechanics, and even I could see the beginner's flaw in the thought experiment for the Many Worlds model.

My best guess is that the OP, understanding the concept of quantum entanglement does not involve communication between particles, is trolling everybody (or just having some fun).

My worst guess is that the OP has gotten so old the OP's mental faculties are slipping and so the OP has achieved subjective immortality but neglected to acquire eternal mental youth.

about a month ago
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Kerry Says US Is On the "Right Side of History" When It Comes To Online Freedom

MisterSquid Re:Sure, I guess I agree (261 comments)

If by "right side" he means leaning towards totalitarianism and increasingly corporatist/fascist views towards online freedoms, then ok, I guess I can agree.

The right side? What a bunch of horseshit. The summary quotes Kerry as saying

And we believe these principles can positively help us to distinguish the legitimate practices of states governed by the rule of law from the legitimate practices of states that actually use surveillance to repress their people. And while I expect you to hold the United States to the standards that I've outlined, I also hope that you won't let the world forget the places where those who hold their government to standards go to jail rather than win prizes.

Which I'm might be a typo ("the legitimate practices of states that actually use surveillance to repress their people") but would be unsurprised to find out he actually said that, Freudian slip and all that.

What really infuriates me is the hypocrisy and the lies. Who is "win[ning] prizes" for holding the US government to standards? Snowden had to flee his country to seek asylum in RUSSIA for crying out loud.

The whole thing stinks and they (Kerry, Obama) have the gall to lie to our faces that they are going to do something about it.

I'm so angry I could spit.

about 3 months ago
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You Can Now Run Beta Versions of OS X—For Free

MisterSquid Re:Apple...Free (201 comments)

It's over... apple is finished..

The summary has one detail wrong.

Yes, developers who do pay a yearly fee have been able to download betas of OS X. Additionally, users identified by various means were invited by Apple to be a beta testers and those invited testers paid nothing to be download, test, and evaluate OS X betas.

I know this because I have been one of those invited testers since 2008.

about 4 months ago
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Russia Writes Off 90 Percent of North Korea Debt

MisterSquid THROUGH North Korea?! (234 comments)

Russia sees this lucrative in advancing the plans to build a gas pipe and railroad through North to South Korea

Seriously? Lay critical crucial infrastructure through North Korea to South Korea?

There's no way Pyongyang would manipulate those rails and pipes in a fit of political pique that seems to happen, oh, once every eight months. Absolutely now way.

about 4 months ago
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The Case For a Safer Smartphone

MisterSquid Re:Statistics (184 comments)

I get the same kind of car every time I rent (Toyota Prius because of low emissions), so the controls are pretty much where I expect them.

However, I know my case is somewhat unusual given there are dozens of Zipcar locations within a 1-mile radius of where I live. This means I can bike to my Zipcar rental, lower the back seats, and put my bike in. Because I have lots of places to find a Zipcar, I can almost always find one of a particular make.

about 4 months ago
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Jimmy Wales To 'Holistic Healers': Prove Your Claims the Old-Fashioned Way

MisterSquid Re:You know what they call alternative medicine... (517 comments)

They are not "nothing", but the psychological mechanism is what does the work. The trigger is in fact "nothing", in that it plays no part in the medical effect.

WTH. Mods on crack.

You said pretty much the same thing I said, except you made a mistake when you said "the trigger is in fact 'nothing'. " The "trigger" is often a sugar pill or some regimen believed not to have a therapeutic effect. Again, as you and I have both said, that is not nothing,

Nothing would be no exposure, either to a placebo or a substance/regimen suspected to have a therapeutic effect.

about 5 months ago
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Jimmy Wales To 'Holistic Healers': Prove Your Claims the Old-Fashioned Way

MisterSquid Re:You know what they call alternative medicine... (517 comments)

So the best argument in favor of your treatment is that it works as well as nothing, which is totally proven to work, sometimes?

You're equating "placebo" with "nothing". A "placebo" is not the same as "nothing". Placebos may activate psychological (or other) mechanisms to achieve their better-than-nothing results but, by definition, they are not nothing.

about 5 months ago
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Level 3 Wants To Make Peering a Net Neutrality Issue

MisterSquid Re:Having built the infrastructure (182 comments)

I think you're ignoring the obvious. Or maybe you're actually saying something of value and I can't parse. Maybe you're trolling.

So, telecoms charge to build and run infrastructure that transports packet traffic.

Internal distinctions a company makes about where to invest revenue and resources to build and run that infrastructure do not change the fact that building and maintaining that infrastructure is the same phenomenological process that moves data across the Internet's networks.

All the bureaucratic details of what a telecom must do to keep the infrastructure running doesn't change this fact.

about 5 months ago
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Getting Misogyny, Racism and Homophobia Out of Gaming

MisterSquid Re:Disable player chat (704 comments)

The "academic" branch of feminism - like all academia - is safely removed from the real world and traffics mainly in the Andrea Dworkin "all heterosexual intercourse is rape" and Starhawk-style schools of radical feminism. This is a holdout from pre-'80s feminism and remains the intellectual vanguard of feminism but is a small niche among women.

As a former faculty of American Literature at at a research university, I can assure you that you have no idea what academic feminism is.

Critical theory, race studies, religious studies, psychoanalysis, film theory, subject spectator theory, semiotics, linguistics, cultural anthropology, and more are all well-understood by and -represented among the scholars and intellectuals who are recognized as feminists. Academic feminists analyze and consider the signs, systems of meaning, legal histories, social histories, cultural artifacts, popular culture, etc. etc, etc. insofar as they affect women and the people to whom women are connected, which would be every human being who has ever lived.

Feminism is multiple, not singular, and the best way to describe what drives feminists is the desire to see women—and the people and collectives to which those women are connected and by which they are constituted—to be empowered and autonomous rather than (as has historically been and, in many contexts, currently is the case) disenfranchised and subjugated.

Seriously, do yourself a favor and understand that movements that promote human welfare are good for everyone. People threatened by feminism don't understand feminism. Feminism is about making things better, flawed as some of its approaches may be.

Here's something old-school style that demonstrates some "academic" feminism from 1991: Donna Haraway's "A Cyborg Manfiesto". That's some old-school cultural anthropological feminism for you that is super awesome, fun, literate, and though-provoking.

Try it and see. Some of these people are smart and amazing. You might be surprised.

(As a straight male professor, it agonized me when young intelligent women would come to my survey on critical theory and proudly announce during our feminist section that "I am not a feminist." I am grateful to have had the opportunity to change some of these young persons' minds.)

about 5 months ago
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Level 3 Wants To Make Peering a Net Neutrality Issue

MisterSquid Re:Federally funded roads (182 comments)

Let me take a shot at incorporating this detail: The buyer is paying the post office's parent company for construction and maintenance of post roads.

Come on. Are you even trying to make a coherent argument?

In the case of the Internet, paying for the "construction and maintenance" of infrastructure is the same thing as paying to have the bits go back and forth across the networks that make up the Internet.

Or are you seriously saying telecomms are charging to "move" ones and zeroes separately from the infrastructure and energy through which those ones and zeroes "move"?

about 5 months ago
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A Call For Rollbacks To Previous Versions of Software

MisterSquid Re:Shades of WinAmp 3 ? (199 comments)

I really don't like when companies turn my app from a standalone product to one requiring a subscription to access new features. BranchFire did it with "PDF Annotate" and Abvio has done it with "Cyclemeter".

Part of the reason I purchased "PDF Annotate" and "Cyclemeter" ($25 and $5, respectively) is they didn't phone home or require a subscription that was looking for an excuse to go belly up.

My guess is once new user growth slows, the companies consider monetizing their current user base (aka "seeking rent"). So, in the next upgrade they introduce subscription services.

I'm sorry, but I'm not interested. At all.

Users should have the ability to roll back any upgrade, including OS upgrades.

about 5 months ago
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Bitcoin Inventor Satoshi Nakamoto Outed By Newsweek

MisterSquid Re:Why? (390 comments)

This is why if you ever do anything in your life that people might want to know about, never EVER answer a request for an interview with anything that could even be used to find a bit of truth. "Off the record" means "this will get into the headline" and everything you say can and will be used against you to get pageviews. The two best responses to a request for an interview are to file a restraining order and if that doesn't work, spend a couple bitcoins on an assassin.

Your advice is a good one for subjects of a possible exposé or smear campaign, however, out of hand dismissing journalists as people without integrity is not in the best interests of an informed public and (probably) in many cases unwarranted.

When I was a university professor, the Chronicle of Higher Education asked for an interview about what it's like to be single and a new faculty (ha!). I agreed to an interview and, on several occasions, said that I wanted to say a few things "off the record" about the behavior of colleagues and the spouses of colleagues (ahem). Some of what I said off the record was juicy and I told my interviewer those things to contextualize my "on the record" remarks.

The article was published, my female colleague who was written up got a couple of marriage proposals, and everything attributed to me was on the up and up.

I know not all journalists adhere to a code of ethics, but I believe that many do. Clamming up when a story needs to get out may protect you, but one needn't be suspicious form the get go.

about 5 months ago

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