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Doctors Say New Pain Pill Is "Genuinely Frightening"

flynt Re: It's just a tool I guess (294 comments)

The Phase III study "Study 801" of the compound under discussion did have an open-label run-in period, *and* was placebo controlled.

I believe the ct.gov link below is the study under consideration. Regardless, the press release mentions the placebo control.

http://clinicaltrials.gov/ct2/...

http://ir.zogenix.com/phoenix....

From the last link:

Zohydro ER was studied in over 1,100 people living with chronic pain who participated in the pivotal Phase 3 efficacy study or an open-label Phase 3 long-term safety study. The efficacy study that enrolled over 500 subjects with chronic low back pain met the primary endpoint in demonstrating that treatment with Zohydro ER resulted in significantly improved chronic pain relief compared to placebo.

about 10 months ago
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Visual Studio Gets Achievements, Badges, Leaderboards

flynt Re:Possible badges for good code (353 comments)

UHF! Only saw it once, probably 15-20 years ago, and still remember that line...

more than 2 years ago
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Bad Science Writer Talks About the Placebo Effect *NSFW*

flynt Bad Science book (131 comments)

I can highly recommend Ben's book "Bad Science". I bought a copy for each of my family members for the holidays. It gives a very realistic overview of the current state of medical research, both from the "mainstream" and "alternative" medicine worlds.

more than 3 years ago
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Bill Gates Is More Admired Than the Pope

flynt Re:Margin of Error? (470 comments)

Well, I am a statistician, too.

I hesitate to say too much about a poll where I am not privy to its final aims, but it seems quite plausible that the point of this poll was to decide who Americans admire the *most*. It looks like they got a pretty clear answer to that question. It would be very hard (i.e., require so many respondents) to design a poll powered to differentiate between each possible candidate at some alpha level.

So, I don't share your criticism of this poll as much as the summary in this article.

more than 3 years ago
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How much TV do you watch in a week, on average?

flynt sports... (385 comments)

I've been able to stop watching almost all television, save live sports. One American football game or baseball game is about 3 hours including the breaks, so it's easy for the TV time to start adding up. I usually don't even care which team wins, I just enjoy the contest.

Living alone, I often just have the TV on while I do other things, like clean or cook.

about 4 years ago
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Lizard Previously Unknown To Science Found On Vietnam Menu

flynt Re:I'll take one (133 comments)

Get ready for McLizard.

more than 4 years ago
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How Do You Manage the Information In Your Life?

flynt Re:Emacs org-mode (366 comments)

Cool, I actually used TiddlyWiki before I found org-mode :). It wasn't at all bad, but since I do everything else in Emacs, org-mode makes sense.

Plus, I use it for more than just organizing information. Like writing reports and authoring HTML and PDF content with embedded R code for example, which obviously is not the point of TW.

Org-mode is essentially to organizers as Emacs is to text editors, i.e., slowly becoming a platform of its own.

more than 4 years ago
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How Do You Manage the Information In Your Life?

flynt Re:OrgMode (366 comments)

Two org-mode posts at the exact same minute :). The uses of org-mode are too numerous to mention in one post, but just to give a little more context... Org is essentially an outliner, event planner, calendar, PDF and HTML authoring system, multi-language code-authoring environment (babel), time tracker, shopping list maintainer, contact database, ...

All this and it's Free Software, too. The mailing list and community is one of the most responsive out there. I've heard many people say that learning emacs is worth it just for org-mode alone.

Check out http://orgmode.org/worg/org-tutorials/index.php for more use cases and tutorials/talks. Incredible piece of software, cannot recommend it enough.

more than 4 years ago
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How Do You Manage the Information In Your Life?

flynt Emacs org-mode (366 comments)

Emacs org-mode (http://orgmode.org). Your life in plain text. Nothing else compares.

more than 4 years ago
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Word Processors — One Writer's Further Retreat

flynt Re:Whatever Works For You (391 comments)

You sound like you'd benefit highly from Emacs org-mode (http://orgmode.org), which functions not only as a day planner and TODO manager, but a plain text authoring system. You can export to many targets, including both LaTeX and HTML. If you haven't seen it yet, definitely check it out, the community is great and the project is growing daily. The latest big inclusion is the ability to embed executable source code for literate programming.

more than 4 years ago
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Xbox Live Pricing To Go Up To $60 Per Year

flynt Re:Greedy (199 comments)

Well, it's $5 a month. Lots of people spend about that at Starbucks every *day* of the week, so I don't it's really a show-stopper price...

more than 4 years ago
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US Students Struggle With Understanding of the 'Equal' Sign

flynt Re:Confusing symbols (1268 comments)

No, we use 'x' over here, too.

more than 4 years ago
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US Students Struggle With Understanding of the 'Equal' Sign

flynt teachers (1268 comments)

Well, no one was born knowing what the equals sign represents. In fact, it's been around only for 500 years. My personal opinion is that until we start forcing graduates of US Education programs to take at least a little math beyond passing out of algebra, the cycle is doomed to repeat.

FTFA, 'Parents and teachers can help the students. The two researchers suggest using mathematics manipulatives and encourage teachers "to read professional journals, become informed about the problem and modify their instruction."'

Uh huh, see point 1 = 1 + 0 above.

more than 4 years ago
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The Great Typo Hunt

flynt Re:less / fewer (416 comments)

The Lund's grocer I shop at in Northeast Minneapolis does it just this way. Another reason I feel justified spending 20% more for my food :).

The fact that they bag your groceries is another reason. It's common in MN to have to do it yourself.

more than 4 years ago
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The Great Typo Hunt

flynt less / fewer (416 comments)

I hope they went to every store with an "express lane for less than 10 items". Shudder.

more than 4 years ago
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Where To Start With DIY Home Security?

flynt Re:Stickers & Insurance (825 comments)

Surely there must be some studies that have randomly assigned security vs. no security to properties in neighborhoods, and then tracked theft?

more than 4 years ago
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Cool, Science-y Masters Programs For Software Devs?

flynt Re:Terminal Degree and Biostat's (150 comments)

I can second this. I did a Master's in Biostatistics, and have a computing background from undergrad. It sounds like this would be a good fit for you, since you're working in a related field already. In the five years I've been working at universities since my Master's, I've had a lot of different experiences, ranging from large clinical trials to military projects. Your computing background will make you a very valuable asset to almost any group you work in, as a lot of stats people are entering from a math background and have little formal programming experience. It's a really good fit for me, because it allows me to balance my time between consulting, designing studies, and programming to analyze them. R and SAS are the two big programs that people in biostat tend to use. I'd look into it if I were you.

more than 4 years ago
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DePaul University To Offer Degree In Predictive Analysis

flynt statistics (71 comments)

There are, however, many quality degree programs in Statistics. As someone who went through one of them, you can largely choose your own mix of theory and practice. I wonder if this isn't just statistics rebranded? I hope it doesn't concentrate too much on certain proprietary software packages. Statistics is like anything else. You can easily produce a bunch of numbers and compile massive books of tables and graphics. But if you don't know the assumptions of each of your methods, and consequently their shortcomings in each situation, you can draw some fairly bad conclusions rather quickly. I just hope this program gives a solid background in theoretical statistical inference, experimental design, and regression analysis, so students understand the 'why'.

more than 4 years ago

Submissions

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flynt flynt writes  |  more than 7 years ago

flynt (248848) writes "Yahoo! Finance is running a story about A.S.A Sports Exchange, who want to create a "stock" market for the public trading of professional athletes. From the article, "The athlete would sell 20 percent of all future on-field or on-court earnings to a trust, which would, in turn, sell securities to the public." Sounds fun, I'll be offering Sidd Finch futures, any buyers?"

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