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In a Cloning First, Scientists Create Stem Cells From Adults

interkin3tic Re:Have their findings been independently reproduc (43 comments)

TLDR: It will probably be about a year to replicate it in humans. Therapy will be several years even assuming it's perfectly safe and assuming no political interference.

It's not a complete departure from previous stuff, though it looks like it is a new technique, so it will need to be independently replicated. Induced pluripotent stem cells took over a year to be reproduced, so there's that.

The next steps are longer, making sure it's safe, and finding a way to harness it.

Clinical trials for stem cell therapies are underway, but I'm not aware of anything so far that is a stunning success, where you put in stem cells and get a regenerated heart, liver, whatever, so we're not quite ready to hit the ground running. Of course, a lot of that was held back by the lack of stem cells which the host's immune system wouldn't reject, so theyr'e a lot closer now. Work on ESC or IPSC advanced being able to harness it, but I don't think there are any clear-cut treatments we know of that were simply waiting on a good source of cells. Spinal cord injuries in mice, I know they're not there yet, you inject cells you've directed somewhat to differentiate into neurons and the recovery rates in mice are nothing miraculous yet. They're improved, but there's the added complication that mice tend to recover from spinal cord injuries better than humans: they're a lot younger than us and can naturally recover better than we can. So it doesn't look like this immediately opens doors to treatments in humans, though it definitely speeds it up a lot. (And I could be wrong about there not being treatments ready to go in humans right now).

On safety, cancer is always an issue with pluripotent cells. Injecting pluripotent stem cells, which can make anything, makes teratomas, which are tumors of mixed cell populations. That's actually a test of stem cells: inject it into a mouse, if you get tumors that have several types of cells in them, you know you've actually got pluripotent stem cells. Teratomas can be complicated to treat though, so injecting pluripotent stem cells into a patient is a terrible idea.

Induced pluripotent stem cells have the additional hazard that you're explicitly turning on cancer-causing genes in the cells to make them that way. They appear to be turned back off, but it's still a concern. Furthermore, there have been suggestions that reverting cells back to a pluripotent state increases the likelihood of mutations. Obviously if the rate of mutation during the process is too high, that can also cause cancer. I haven't been following that literature, so I don't know if that's been discarded with IPSC. And I don't think it's been done with this new technique, though I haven't read the paper.

So there's no clear timeline, which is disappointing, but whatever the timing was going to be, it's shorter now, so yay.

yesterday
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Plant Breeders Release 'Open Source Seeds'

interkin3tic Re:Shame this happened (130 comments)

I don't see how that changes things. He was collecting discarded trash from his neighbors, so he didn't enter into agreements there. Monsantos patents on glyphosphate are expired, so using round-up to enrich the trash doesn't change anything. Sneaky, maybe, but seeds blowing off your property are no longer yours.

I could see how selling the seed would get him into trouble with patents, but that's only reasonable if you accept that patents on living things are reasonable.

yesterday
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Snowden Queries Putin On Live TV Regarding Russian Internet Surveillance

interkin3tic Re:"I USED to be working for an intelligence servi (387 comments)

Well, now the intelligence services work for him. You don't say you currently work as a servant even if you used to be a servant yourself and currently use servants.

2 days ago
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Snowden Queries Putin On Live TV Regarding Russian Internet Surveillance

interkin3tic Re:In Mother Russa... (387 comments)

I'm guessing because either 1. He sees cable news and thinks we're so stupid we believe anything, not realizing we only believe anything if it comes from "real americans" or something like that, or 2. He can.

2 days ago
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Snowden Queries Putin On Live TV Regarding Russian Internet Surveillance

interkin3tic Re:Voluntary? (387 comments)

Hypocrisy and propaganda? Try ignorance: most of the people calling him traitor are too stupid to remember what was actually going on at the time. They just hear someone say he hurt the US and are bleating for his blood without understanding what happened. Is that better? Well, no...

2 days ago
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Snowden Queries Putin On Live TV Regarding Russian Internet Surveillance

interkin3tic Re:Useful Idiot (387 comments)

Remember that reputation isn't an on/off switch. He's gained a lot of reputation with the NSA revelations. How much of that does "this could be useful to putin" reduce it? 1%?

Perhaps he thought it would start a debate. Does it reduce his reputation if he honestly thought he could start another change in his host country?

2 days ago
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RCMP Arrest Canadian Teen For Heartbleed Exploit

interkin3tic Re:Good. (103 comments)

Boredom and isolation often leads to deviant behavior. How many of us got into nerd stuff because we were bored and wanted to know if we could "hack" something we weren't supposed to? I started reading 2600 before I got my drivers license. It was, fortunately, far over my head, and thanks to dialup, even if it weren't, that would be almost as boring as homework, so I never actually did anything.

I wonder what the solution is. My kid isn't going to have those limitations, even comcast is vastly superior to dialup, and he's getting a head start on using computers.

Maybe I'll have to stick with apple products, make sure he stays in the walled garden and out of the CRA website.

2 days ago
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Industry-Wide Smartphone "Kill Switch" Closer To Reality

interkin3tic Re:Yay for government!!! (137 comments)

I think that could be valuable: if we start allowing street cops to use this to delete evidence of their pointlessly aggressive tactics, that's a GREAT sign to leave the country ASAP.

2 days ago
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Bidding At FCC TV Spectrum Auction May Be Restricted For Large Carriers

interkin3tic Re:Government picking favorites (91 comments)

And tell me this... Where can you find daily national/world news with the same quality as the approx. 4am newscasts on CBS/NBC/ABC? BBC World Service looks like crap by comparison, though easily better than CNN/MSNBC/FauxNews of course.

If I'm up at 4AM, the TV guide channel is about the level of journalism I'm capable of appreciating.

Also, does the BBC website not work at 4AM? Because one could just browse that. What's so bad about the BBC world service? I'm asking honestly, I've never been a fan of video news, and never been a fan of anything that early in the morning.

2 days ago
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Kids Can Swipe a Screen But Can't Use LEGOs

interkin3tic Re:How to describe a pre-schooler (352 comments)

The degree matters though. If it's worse than normal, it might be a good point. I doubt anyone has done a controlled study and quantified the effect, but just in theory it COULD be a reasonable statement.

2 days ago
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Kids Can Swipe a Screen But Can't Use LEGOs

interkin3tic Re:Parents fault (352 comments)

No no no! You're totally selling it wrong! You've got to say it's building up! Lemme give you an example:

"Studies show that the CRACK BABIES OF THE 80'S are now having crack babies of their own who are EVEN WORSE and UNABLE TO PLAY WITH LEGOS AND INSTEAD HAVE EVIL HACKING SKILLS!!!"

See? Three offers of employment in my inbox from Huffington Post already!

2 days ago
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Google Looked Into Space Elevator, Hoverboards, and Teleportation

interkin3tic Re:space elevator failure (98 comments)

I think it's pretty likely that people smart enough to make a space elevator will be smart enough to consider what happens when it goes wrong. Whether they will find it worthwhile to do anything about it is a different story, but it will be considered, that's for sure.

3 days ago
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Google Looked Into Space Elevator, Hoverboards, and Teleportation

interkin3tic Re:Information = Wealth = Power (98 comments)

I'm always hearing about google being the target of Steve Jobs' ego-driven "thermonuclear war" with patents. What are some examples of google patent trolling as you've suggested? I'm not saying I think google is actually behaving unlike a corporation, just that I don't know of any examples of them doing what you're saying they're doing.

3 days ago
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Student Records Kids Who Bully Him, Then Gets Threatened With Wiretapping Charge

interkin3tic Re:Rewarding the bullies... (789 comments)

High profile murderers who make no attempt to conceal their crime usually do it more for attention. They might tell themselves it's for higher reasons, like they hate that politician or that race, but really it's that their egos aren't satisfied. Same with school shootings. They shoot up their schools because they want attention from their classmates. With columbine and other school shootings, we like to tell ourselves they're going rambo because they were bullied, and the shooters did too. We tell ourselves the lie because it's easier to think kids only do this when put under extreme pressure by bullying, we don't like to think that some kids are just psychopaths who are evil. They told themselves it was because of bullying because that sounds better than "We're bored and want attention."

Although early media reports attributed the shootings to a desire for revenge on the part of Harris and Klebold for bullying that they received, subsequent psychological analysis indicated Harris and Klebold harbored serious psychological problems. According to Dave Cullen, Harris, who conceived the attacks, was a "cold-blooded, predatory psychopath" and an intelligent, charming liar with "a preposterously grand superiority complex, a revulsion for authority and an excruciating need for control". In Cullen's assessment, Harris lacked remorse or empathy for others, and sought to punish them for their perceived inferiority.

wiki

3 days ago
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Intuit, Maker of Turbotax, Lobbies Against Simplified Tax Filings

interkin3tic Re:Get rid of income Tax (415 comments)

Wait, how is the progressive income tax the "most regressive tax possible?" You're suggesting they indirectly do what sales taxes directly do. Wouldn't they be at least tied with sales taxes?

3 days ago
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Intuit, Maker of Turbotax, Lobbies Against Simplified Tax Filings

interkin3tic Re:Not even much money (415 comments)

To be fair, that number is probably a lot lower than it would be in sane political climates. Mention taxes and the voters go insane. Mention much of anything besides jobs and yay USA and they'll go insane. "They're trying to take away your refund!" will get a lot more traction than "death panels" did.

3 days ago
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Intuit, Maker of Turbotax, Lobbies Against Simplified Tax Filings

interkin3tic Re:Not even much money (415 comments)

The lesson here is that neither pure capitalism nor pure socialism ever exist long in the real world and we should probably stop talking about economics in theoretical terms.

3 days ago
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Climate Scientist: Climate Engineering Might Be the Answer To Warming

interkin3tic Re:the 70's called (341 comments)

What are you saying? Surely you're not suggesting that any scary scientific predictions made in the 70's cannot as a rule come true.

I'd suggest some of those dire predictions were self-defeating predictions anyway. CFCs and the ozone hole for example lead to a reduction in CFC emissions. Politicians occasionally listen to scientists.

3 days ago
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U.S. Biomedical Research 'Unsustainable' Prominent Researchers Warn

interkin3tic Re:The problem is that too much of it is state bas (135 comments)

Okay, I think you need to take your own advice, I didn't think you were suggesting abolishing government funding. I'm suggesting that we keep the same amount of state funded research, but put it into higher risk grants and let the private sector take over more sure projects, which will get the benefits you're hoping for.

3 days ago
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Paper Microscope Magnifies Objects 2100 Times and Costs Less Than $1

interkin3tic Re:dupe (89 comments)

I guess not enough people are voting in firehose. Whining about the outcome is fun and all, but you could do something about it. This is also true of the republican and democratic parties, through the primaries, but I digress.

3 days ago

Submissions

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terrorist group hosted on dutch server

interkin3tic interkin3tic writes  |  more than 4 years ago

interkin3tic (1469267) writes "'Columbia Reports' reports that a Spanish non-profit organization is hosting the website of Colombia's second largest guerrilla group, National Liberation Army (ELN), on a server in the Netherlands. ELN is on a terrorist blacklist, hosting a website for a group on the blacklist is punishable depending on the content.

The article goes on to state that the ELN website is political in nature, criticizing president Alvaro Uribe and the US military. The website is in Spanish, there is a link to it in the article, if you don't read Spanish, resist the temptation to click on it so we don't Slashdot it and contribute to the censorship."

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