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Artificial Pancreas Shows Promise In Diabetes Test

jvp Re:so much for the stem cell hype wagon (75 comments)

A few tens of millions, and a bionic pancreas is nearing usability

tell me again why the bandwagon for stem cells

A child growing up with Type-1 is going to fare a lot better in life with a completely internal, biological solution to the problem versus having a device attached or implanted. So too will adults. Your thought process is a bit short-sighted, it seems.

about 2 months ago
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Artificial Pancreas Shows Promise In Diabetes Test

jvp Re:Measure blood directly (75 comments)

It seems as though the big problem with this technology is that it's not measuring blood directly. What are the barriers to placing a sensor more-or-less permanantly inside the body that can test blood directly and the send, via radio or whatever, commands to an external insulin pump to dispense insulin?

Fun problems that aren't insurmountable, but expensive and very challenging. You have the issue of potential infections and rejection, first and foremost. Any insulin pump wearer knows that the site he or she is using needs to be ripped out and replaced every 3 days or so. Why? The body will muck it up via its internal self-defense mechanisms. The same thing would happen to a foreign body fully immersed inside the body.

Power supply. Something that's transmitting constantly or regularly is going to need a power source. Do you make it something that attaches to the outside of the skin for power (ie: a small battery)? Or cut the person open whenever the battery starts flaking out? If the latter, we have new members of the zipper club instantly.

about 2 months ago
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Artificial Pancreas Shows Promise In Diabetes Test

jvp Re:Marketing hype (75 comments)

]but when done right the results really are quite useful.

All I ask is that you don't judge the entirety of an approach based on your experience with one flawed implementation.

Show me it "done right" with years(!) of lab evidence, trials including hundreds (if not thousands) of individuals, and perhaps I'll believe you. Oh, and when you provide said data, don't be an "Anonymous Coward" about it, either.

No, blood tests aren't 100% accurate. They are, however, a far, *FAR* more accurate way to get an idea of levels than using interstitial fluid. And, as it turns out in this case: accuracy counts. A lot.

about 2 months ago
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Artificial Pancreas Shows Promise In Diabetes Test

jvp Re:Pease hurry (75 comments)

Doughnuts aren't going to eat the selves(sic).

Is it bad that I know that a Dunkin Donuts Boston Kreme donut has about 32g of carbs? ... :-D

about 2 months ago
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Artificial Pancreas Shows Promise In Diabetes Test

jvp Re:Warning: Snarky comment (75 comments)

The first company to cure diabetes is going to make a shit ton of money.

My prediction regarding Type-1 is this: The computer geeks are going to come up with a pretty damned good solution before the geneticists do (the tech in the aforementioned article is *not* that). But ultimately, it'll be the geneticists that figure out how to cram new Islets of Langerhans into the pancreas and keep them protected from the immune system without the anti-rej drugs.

The former solution will be an acceptable stop-gap measure for however long it takes the geneticists to cook up the latter.

about 2 months ago
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Artificial Pancreas Shows Promise In Diabetes Test

jvp Re:Isn't this why we have Mexicans? (75 comments)

Anti rejection drugs > death.

Yeah. Maybe. But probably not, depending on whether you happen to get sick one day...

about 2 months ago
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Artificial Pancreas Shows Promise In Diabetes Test

jvp Re:Drop everything to avoid Diabetes II (75 comments)

In a very long list titled - Stupid Things I Have Done ---- ignoring my doctors warnings on my blood sugar levels ranks right around #1.

While your contribution to the thread is admirable, it's centered around Type-2. We're discussing the genetic, auto-immune disease known as Type-1.

about 2 months ago
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Artificial Pancreas Shows Promise In Diabetes Test

jvp Re:Isn't this why we have Mexicans? (75 comments)

Why are we screwing around with artificial organs when we can have the real deal?

He. Joking aside, I know someone who actually did get a pancreas transplant, and his Type-1 was *essentially* cured. However. He eats massive handfuls of anti-rej drugs with every meal, all to keep that pancreas functioning. IMHO, not a good trade. At all.

about 2 months ago
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Artificial Pancreas Shows Promise In Diabetes Test

jvp Re:Marketing hype (75 comments)

Yep. I'm a *big* fan of my insulin pump, but the included "Constant Glucose Monitoring" device that the pump's company touts as "FDA-approved artificial pancreas!!one11eleven!!" is anything but. It's measuring interstitial fluid, which is *randomly* accurate in *random* people at *random* times. It can neither be trusted, nor should be. And I've since stopped using the CGM side of the pump.

The tech that they're talking about in this article is the same idea: measure interstitial fluid and make insulin decisions based on that. Bad. Ju. Ju.

We need some way of measuring blood glucose levels from, ya know, actual *blood*, without the risk of causing infections. Until we get that, no bueno. Just pass on it.

about 2 months ago
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GM Names and Fires Engineers Involved In Faulty Ignition Switch

jvp Praise in Public... (307 comments)

...punish in private!

Unlike a lot of nay-sayers, I'm a big fan of GM and will continue to buy specific products from them. However, I'm *not* a fan of this move. Always praise in public and punish in private. They should have simply released a press statement with something like, "We've determine who was responsible for this ignition switch issue, and they've been terminated or dealt with accordingly." Done. Naming them serves no purpose whatsoever.

about 3 months ago
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Adobe Creative Cloud Services Offline (Again?)

jvp Re:How long must we suffer? (164 comments)

Looks like it's back up and running. I can sign into the CC application as well as their various web properties.

about 3 months ago
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Adobe Creative Cloud Services Offline (Again?)

jvp Re:Adobe Photoshop Down (164 comments)

Your main workflow, on the other hand, shouldn't be constrained by your network. There's so many things that could wrong in that chain.
1. your computer
2. your router/LAN
3. your ISP
4. the internet (yeah, sometimes everything breaks)
5. Adobe's servers

as opposed to just (1) if you've purchased a static installation.

And this is where some clarity is needed, I suspect. Again, as has been stated numerous times in this thread: the applications will continue working as long as they have already validated your subscription. For instance, I just fired Photoshop and Premiere up. Both popped open a dialog that said, basically, "Hey, we can't validate your subscription, but you can continue using the app until July 28, 2014. If we can't connect by then, your product will stop working."

There are a *FEW* folks that will run into problems authenticating and consequently not being able to use the product. Why their machines haven't authenticated in the past is beyond me. But the dialog is clear: I have almost 2.5 months! I suspect most people (other than those trying to do new installs... UGH!) are in the same boat.

Is it ideal? Oh hell no. Is there anything we can realistically do about it? Well, we can leave Adobe if that's our choice. But as has been pointed out elsewhere, their products really *are* the best out there. I know comparing FCPX and Premiere Pro is almost laughable (and I've done it on my new Mac Pro). As optimized as FCPX is for the new Macs, Premiere is *still* faster for what I do. No one else really has a Photoshop. Or a Lightroom if you don't need PShop's grunt.

Another solution: stick with the CS6 versions of the suite assuming you've already purchased them. The problem with that is: they're not being developed any more, and will *only* have major bug fixes done. What? Can't run them on the latest OS de'jour? Tough shitski. You're outta luck.

I'm not trying to defend the CC sub model because it sucks the big'n. But I *like* Adobe's software, so I'll continue p[l]aying along. If something better appears, I'll look into it.

about 3 months ago
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Adobe Creative Cloud Services Offline (Again?)

jvp Re:NO Photoshop for you! (164 comments)

Adobe, incompetent? I wasn't aware that there was any doubt about that?

I think their application developers are top notch, actually. Their IT and infrastructure guys, on the other hand? Not... so much. If a "competence injection" could be given, I'd aim it towards their inf guys, not their devs.

about 3 months ago
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Adobe Creative Cloud Services Offline (Again?)

jvp Re:The best part... (164 comments)

The best part is that this is happening on the eve of Adobe canceling sales of perpetual licensing to Adobe Creative Suite products

I attached a comment to this article before it was posted, but it looks like timothy nuked it before he made it live.

This "sniff test" for this is: hack. Not maintenance. I say that because the authentication system went down, as best I can tell, around 1700EST Wednesday. Afternoon maintenance is not unheard of, but it seems like a silly and unlikely thing to do.

Hope I'm wrong about that.

about 3 months ago
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Adobe Creative Cloud Services Offline (Again?)

jvp Re:NO Photoshop for you! (164 comments)

Fortunately, as I pointed out: you can still the CC apps while this debacle is being un-FUBAR'd. That is unless it takes them up to 2 months to fix it, at which point the app will no longer be able to authenticate and validate your subscription. THEN it's "NO Photoshop for you!"

If it takes them that long to fix this, then they are truly, completely, and absolutely incompetent...

about 3 months ago
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Adobe Creative Cloud Services Offline (Again?)

jvp Hack? (1 comments)

I should have put this in the main body but: the sniff test for this seems to indicate a hack, given the time of day the authentication system tanked (circa 1700EST). It's *unlikely* to be due to maintenance, specially at that time of day. And catastrophic hardware and/or software failure should be recovered by now.

about 3 months ago
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Compared to my 1st computer's memory ...

jvp Re:Missing alternative (587 comments)

Yeah, for a TI-99/4a with it's 256 bytes of actual CPU 'scratchpad' RAM on the TMS9900's 16-bit system bus vs today's 16GBs is, what, about 67 million?

I had the same challenge, but today's computer has 48GB. There aren't enough 0s in the poll. :)

about a year ago
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One Year After World IPv6 Launch — Are We There Yet?

jvp Re:"Switch over to IPv6" is very misleading (246 comments)

As for me personally, I too own a dual-stack router (RVS4000) but Comcast is trying to nickel and dime me on switching to IPv6. They want me to buy a new cable modem (because I refuse to pay the "rental fee")

Are you in one of the markets they have IPv6 available? I didn't think they'd rolled it out everywhere yet.

Further: are you on a D2 or D3 cable connection? If you're still on a D2 modem, I'd recommend taking the plunge and bumping up to D3. IPv6 becomes much easier, and you'll have a bigger speed potential.

about a year ago
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One Year After World IPv6 Launch — Are We There Yet?

jvp Re:"Switch over to IPv6" is very misleading (246 comments)

I never stated that what I said was exact fact ... only what I was speculating.

Perhaps you were speculating. The tone of your post was one of (an attempt at?) knowledge. And it's a bit misguided.

The insight I've gained tells me that NO ONE is ready to simply flip a switch; it's going to be a painful, multi-year migration.

I don't want to speak for Morgaine, but I suspect this last sentence in your post is probably one of the things he took issue with. You're making it sound like administrators and network engineers need to

flip a switch

to migrate to v6 and that's not the case. It's more like flipping a switch and adding IPv6 to the game.

There's a distinct and important difference.

Where you're partially right is the challenge with old network gear that can easily handle IPv4 in hardware. A lot of those devices aren't capable of handling v6 in hardware, and possibly not even in software depending on how old they are. Enterprises with established network hardware are often loathe to swap them out for newer devices. If a switch needs to be flipped, it's that: replacement of old, legacy (and quite frankly, crappy) hardware.

about a year ago
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One Year After World IPv6 Launch — Are We There Yet?

jvp Re:"Switch over to IPv6" is very misleading (246 comments)

And once enabled, IPv6 works totally happily and transparently alongside IPv4 in the home network and at the server end, so there are no "switch over" issues. IPv4 continues to work exactly as it did prior to enabling IPv6.

What he said. Every device in my house is dual-stacked and happily running with both v4 and v6. It took all of 10 minutes to create a new account with the likes of Hurricane Electric and then set up my tunnel. I've got an entire /48 allocated to my home, which is more than I need for ever atom in the building. :)

Well... maybe.

The tunnel broker solution is a very easy one for those of us not connected to an ISP that provides a native IPv6 solution (yet?) And once you enable it, most of your browsers and whatnot will automatically try the v6 address they get back from an FQDN look-up.

As an aside, I recently tried to create an IPv6-only Linux VM on my VMWare rig. I wanted to see if enough of the infrastructure services were available via v6 to work. It worked fine; NTP, yum upgrades (CentOS), etc all work on it. The only interesting challenge is my NAS at home doesn't yet support NFS via v6.

about a year ago

Submissions

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Adobe Creative Cloud Services Offline (Again?)

jvp jvp writes  |  about 3 months ago

jvp (27996) writes "Adobe's authentication system for its Creative Cloud as well as its website services is down, and has been since Wednesday (14 May) afternoon. What this means: If you're a Creative Cloud subscriber, you can't log into your account via the desktop application. Online services such as the fonts are not available. Applications (eg: Photoshop, Premiere, etc) will continue to work.

Softpedia has a nice article on it, but their time frames are off quite a bit. http://news.softpedia.com/news..."

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