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Function of 80% of the Human Genome Charted

rnaiguy Re:What about Selection? (112 comments)

Just because it doesn't code for protein doesn't mean it isn't turned into RNA, or bound by some protein to regulate some other part of the DNA. Some of it is selected for, we just didn't know where to look to find conservation, or the nature of that conservation. It's easy to pick out regions coding for protein because there are some fairly strict rules for these, so it's easy to find conservation. For some of these non-coding regions, the precise sequence and location is not important, and many similar sequences spread over a wide location range can work just as well. Alternatively, some of these regions are selected to have a certain structure at the RNA stage, which can be satisfied by many different sequences, and undetectable by most methods. Lastly, and most excitingly, these are regions that are evolving quickly. While the function of a protein may remain similar between two species, it may need to be produced in a different time and place in different species. These may be the places in our genetic code where we find out what makes us human. Thus some of these regulatory elements are not conserved between species (though many are!).

Now none of that rules out the existence of regions of DNA that do little or nothing and can be mutated without consequence. There are definitely such regions in the genome.

i hope that cleared something up

about 2 years ago
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Scientists Store Entire Textbook In DNA

rnaiguy Re:How fast? (160 comments)

Given the machine they used in the paper to read the data back, it would take about 10 DAYS to read out the data they encoded. The problem is that it takes that time to get any data at all. So they could parrallelize it to get better MB/sec (or realistically MB/hr), but with current tech, the latency is 10 days, with a theoretical maximum of 100gigabits of uncompressed data read out in that time, (but realistically much less since they rely on redundancy to reduce error, and have overhead for their encoding system).

about 2 years ago
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Arizona H-1B Workers Advised to Carry Papers At All Times

rnaiguy Re:Isn't it the law already? (884 comments)

So, what happens when I get pulled over, and the police officer asks for proof that I am here legally, and I inform him that I am a naturalized US citizen (which I am), and thus am not required to carry any such paperwork? What if I was Illegal and said the same thing?

If the police can not question that lie, then the law is a farce anyway. If they can, then a whole lot of citizens are going to have their rights violated.

more than 2 years ago
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Iran Claims New Cyber Attack On Its Nuclear Plants, Blames US and Allies

rnaiguy Re:Bad Idea? (289 comments)

This is not a nuclear power plant. It is a uranium enrichment facility. The amount of enriched uranium involved in a given accident would be small, and insufficient to cause a catastrophic meltdown.

more than 2 years ago
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Close Approach By Asteroid 2012 BX34

rnaiguy Re:"at that size..." (55 comments)

"...news that asteroid 2012 BX34, 11 meters wide..."

more than 2 years ago
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Genome Researchers Have Too Much Data

rnaiguy Re:Compression (239 comments)

when faced with the 'blistering' speed of developing in C, I'm willing to accept slower runtimes.

I imagine that it would be a different story for someone making production code for distribution, but most of my stuff gets used a few times, and only within the lab.

more than 2 years ago
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Genome Researchers Have Too Much Data

rnaiguy Re:Compression (239 comments)

I've actually found it FASTER to keep the data compressed. Hard drive read speed has become a real bottleneck with big datasets. Python has built-in gzip support, so working with it has become trivial for me :)

more than 2 years ago
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US Student Loans Exceed $1 Trillion

rnaiguy Re:heh (917 comments)

Wow, way to spread misinformation. I can assure you that while there are biases toward the wealthy in the Ivy League (mainly due to inequities in access to primary education, though a small part is due to legacy/connections), there are no financial barriers to entry into these schools for students who are willing to work hard and apply themselves. Most of the people I knew who went to these schools are firmly in the 99%, and many of them in the bottom 50%.

more than 2 years ago
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NAND Gate Built From Bacteria

rnaiguy Re:Nice, but not small (63 comments)

However, this NAND gate comes with a suite of chemical sensors attached. Many of which can be used as inputs to the gate. I doubt that can be fabricated in a 300nm circle.

more than 2 years ago
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Google Reaches $500 Million Settlement With Feds

rnaiguy Re:Question (172 comments)

If that is the case, then i retract my statement. With google's domination of the industry, it could easily have gotten $500 mil. However, the statement in the article is quite vague now that I read it again. Did you see a better explanation elsewhere?

more than 2 years ago
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Google Reaches $500 Million Settlement With Feds

rnaiguy Re:Question (172 comments)

from TFA:

"Drug and health care advertising generated about $1 billion in Internet spending last year and is expected to grow to nearly $1.9 billion by 2015, according to the research firm eMarketer Inc."

That's $1 billion total spending, not profit, and not only Google. I don't think Google generated anywhere near $500 million from it.

more than 2 years ago
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Last NASA Spacewalk Marks End of Era

rnaiguy Re:Agreed (80 comments)

Actually, until they get off on the ground. Shit happens...

more than 3 years ago
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Study: Fair Use Drives Large Part of US Economy

rnaiguy Re:4.5 trillion? That's lost licensing revenue!!! (70 comments)

"Our thieves should be able to get no less than 450 billion in fees from these thieves. Lawyers, to the courtrooms!!!" - Unknown RIAA exec.

FTFY

more than 3 years ago
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The Dark Side of Making L.A. Noire

rnaiguy Grad school (242 comments)

So they work like graduate students, just with more pay.

more than 3 years ago
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Google Launches Google+ Social Network

rnaiguy Re:Oh my. (368 comments)

Not only is it not prominent, it's a pain in the ass and very awkward to use. This is a much better solution.

more than 3 years ago
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Human Genome Contaminated With Mycoplasma DNA

rnaiguy This makes very little sense (123 comments)

When you assemble a genome, you assemble the sequences into chromosomes based on overlap with other sequences. This contamination should not match up properly, or be assemble into its own "chromosome".

The whole "evolution" thing is the biggest sensationalist bullshit I've ever heard. Ignore it.

As was mentioned in another comment, it seems like the summary is misleading on the "contamination" actually being in the genome sequence.

more than 3 years ago
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WikiLeaks Releases Guantanamo Prisoner Files

rnaiguy Re:Casio F-91W wristwatch (426 comments)

And we'd know EXACTLY where to find them.

more than 3 years ago

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