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Doomsday Clock Moved Two Minutes Forward, To 23:57

tmosley Re:Be a scientist and look at the data (171 comments)

The same one that will do anything (but generally prefers to do constructive things as that is lower risk) for a small (large over time) chance at performing the reproductive act.

7 hours ago
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Doomsday Clock Moved Two Minutes Forward, To 23:57

tmosley Re:Be a scientist and look at the data (171 comments)

I'd say it has more to do with the way the human brain processes skin color than poverty (blacks account for most of the prison population even accounting for socioeconomic status) or "race" (there really isn't such a thing--more genetic diversity in the human population of Africa than the rest of the world combined). Dark skinned (not just black Africans) people as a whole will, over the long term, always wind up making up the bulk of the population of the lowest tier of society, no matter which society they are in. Studies on young children show that the brain associates darker skin with masculinity, aggressiveness, and misbehavior, while white skin is associated with good behavior, trustworthiness, and femininity.

Following this line of thought leads to a societal setup that, when compared to history, has created the only successful black societies--segregation. Places like Harlem and Greentown were successful prior to integration (or their total destruction in the face of the prospect of integration), as were civilizations like Nubia, Mali, and Great Zimbabwe, which successfully traded with civilizations populated by lighter skinned peoples.

Many of the problems associated with dark skinned people around the world can thus likely be attributed to societal feedback loops (self-fulfilling prophesies) and brain drain, where the best and brightest "get out of the ghetto" rather than taking charge of the ghetto and making it a better place. Of course, many black societies also have their own cultural problems (corruption in Africa, anti-intellectualism in America, for example), but those don't explain the more widespread effect, and the fact that SKIN COLOR in and of itself is the most powerful predictor of IQ, no matter whether you are looking at America, India, Africa, Australia, or anywhere else.

If you think this post is racist, then you think reality is racist and there is nothing I can do for you.

7 hours ago
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Google Search Will Be Your Next Brain

tmosley Totally Amazed (45 comments)

I'm totally amazed by the progress these guys are making. Layering two modules together to allow image tagging is a stroke of genius, and seems to me that that lays the foundation for the Singularity RIGHT THERE.

I kinda wish they would turn some of that computing power toward some blue sky science (imagine deep learning analyzing CERN data, or Hubble imagery, or the human genome, or protein folding, or all of the above). Maybe use some of the resultant knowledge to design and fabricate better components for itself.

about a week ago
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Silicon Valley's Quest To Extend Life 'Well Beyond 120'

tmosley Re:Death is a creative force. (272 comments)

Don't compare apples to oranges. A more apt analogy would be to say that your grandmother left your grandfather after she caught him cheating. Even if she hadn't caught him that time, she would have eventually, and the same thing would have happened. Empires don't last because their rulers do the same stupid things over and over. You might claim that Venezuela would be doing fine if Chavez was still alive, but the fact is that he just died before the effects of his policy came into clear view. His successor has carried out the exact same policy, and the result is the same as it would have been with him.

Funny how you impune Putin, demonstrating your clear failure to learn from the Nazis, ie you are a slave of Western propaganda, just like the average German was a slave to Nazi propaganda. Had those same people been immortal, they would have seen Hitler for what he was, having lived through the same shit in Rome before the fall. Had YOU lived through Nazi Germany, you would see what is going on in the US for the exact same.

People talk about history repeating/rhyming for a REASON, and you have demonstrated your failure to learn from it quite clearly. Maybe if you lived another five hundred years, you could point out when a politician is clearly a power hungry fascist and get him banned from politics before any harm can be done, drawing on the lessons you will learn over the next ten or twenty years.

about two weeks ago
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Silicon Valley's Quest To Extend Life 'Well Beyond 120'

tmosley Re:Why tech zillionaires fund life exension resear (272 comments)

This isn't a marketed use, it's one that I discovered. We were talking about low-hanging fruit, remember? This isn't even my specialty, I just know how to read scientific papers, and how to put two and two together.

You have a very confrontational attitude here. What is wrong with you? We are talking about bleeding edge stuff (ie something that I as in ME as in MYSELF discovered, implying this would be really easy stuff for researchers to systematically explore), and you start blathering about how there aren't three human trials on it. I'm not trying to fucking sell you anything, I'm just reporting something that has an effect that by far any possible placebo effect, ie it is effecting things that I never expected, and noting that it is something that SHOULD HAVE BEEN DISCOVERED DECADES AGO, but no-one has been researching aging. As an example of unexpected effects, my bowels move much faster than they used to (presumably due to increased output of the mucous membranes there--ever notice how kids will take a crap at any time of the day?), my libido has increase 2-4 fold, my night blindness has disappeared, and I'm suddenly having extremely vivid dreams that are creative and logical that I can remember when I wake up.

You don't want to believe some guy on the internet, then fine, but don't try to tell me to discard my own observations, and don't try to tell me that there isn't low hanging fruit in this field.

about two weeks ago
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Silicon Valley's Quest To Extend Life 'Well Beyond 120'

tmosley Re:Why tech zillionaires fund life exension resear (272 comments)

Why would you think that only neurons could be emulated? Didn't you ever see The Matrix? Imagine that, only everyone is completely inside (ie no goo pods or needles in the brain), no-one dies (or get sick, or injured), and, like with the loading program, there is no limit to the goods (or services) that can be conjured from nothing.

Not only that, but with extra resources, you could not only have the senses you have now, you could gain any number of other ones. See the entire spectrum of light, or have some of Neo's code-vision, or be able to feel and move arbitrary objects (ie telekinesis). And those are only a few of the things my tiny little ape-brain could come up with.

about two weeks ago
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Silicon Valley's Quest To Extend Life 'Well Beyond 120'

tmosley Re:Why tech zillionaires fund life exension resear (272 comments)

Nicain as nicotinic acid produces severe side effects (flushing, vomiting) at the effective dose. Nicotinamide riboside doesn't. The one that I found, nicotinamide (sold as niacinamide) doesn't either, so long as you stay under 3 grams a day.

The current state of the research shows that it effects cellular health/aging markers, effectively turning the cells of old mice into the cells of young mice. Last I heard, the same group that showed that was going to start a new study that looked at their actual lifespan.

Current thinking is that NAD facilitates communication between the nucleus and mitochondria.

This is a real stunner, not because it is so new and amazing, but because this is about as low hanging of a fruit as you can get. I learned NAD and its role in cellular metabolism in biochemistry class. It had been observed to decline with age. But no-one ever thought to try increasing the concentration to counter the aging process or at least some of its side effects!

about two weeks ago
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Silicon Valley's Quest To Extend Life 'Well Beyond 120'

tmosley Re:Why tech zillionaires fund life exension resear (272 comments)

You really seem to cherish your pessimism. NAD supplementation has been shown to modify cellular markers associated with aging in middle aged and elderly mice back to those of young mice after just a week. Never mind the fact that b-vitamin complex shots (which include niacinamide) have been known to instantly improve health for ages.

about two weeks ago
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Silicon Valley's Quest To Extend Life 'Well Beyond 120'

tmosley Re:The longer you live...Cancer could be your rewa (272 comments)

But some cell rods don't shorten when they divide, namely stem cells and germ cells.

I would use the analogy that lengthening telomeres is to preventing aging the way building taller buildings is to lifespan of jumpers. Better to just stop people from jumping in the first place.

about two weeks ago
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Silicon Valley's Quest To Extend Life 'Well Beyond 120'

tmosley Re:Why tech zillionaires fund life exension resear (272 comments)

Yes, the Ship of Theseus is exactly the correct path to go. Communication is required to maintain continuity of self, ie the "soul". "You" are not the sheet music, nor the instruments, nor the people who play them, but rather the music itself. Your performance can be extended indefinitely by replacing the fragile human players with synthesizers of sufficiently high quality during breaks in a particular instrument's performance. Might not even notice the difference.

about two weeks ago
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Silicon Valley's Quest To Extend Life 'Well Beyond 120'

tmosley Re:The longer you live...Cancer could be your rewa (272 comments)

A weakness of neural nets is that they often bypass hard work (like reading the entirety of a post) by pattern recognition (reading just the first part and assuming the rest of the post is equally inane, rather than cleverly contradictory).

I need an upgrade. Sigh...

about two weeks ago
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Silicon Valley's Quest To Extend Life 'Well Beyond 120'

tmosley Re:Death is a creative force. (272 comments)

Khan's empire still would have collapsed, as would Stalin's. And likely faster. Not only that, but the lessons of history would have stayed learned, rather than us having to repeat them over and over. Khan would be able to tell us today that just printing money feels great for a few decades, but it inevitably leads to destruction, while Stalin could tell us that Communism simply doesn't work. Not only that, but the people who lived under them would have learned how much power they had after going through some number of revolutions, and would never again allow people to have arbitrary authority over them.

Stop trying to justify things just because you think they are inevitable.

about two weeks ago
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Silicon Valley's Quest To Extend Life 'Well Beyond 120'

tmosley Re:Population control (272 comments)

Not really. Our population is controlled to a much greater extent by birthrates than death rates at the moment. And most people are unlikely to have more than one set of kids. By the time they are 60 (but vital as a 25 year old), they will have had more than enough. Many, noting that their lifespans have been extended, will opt not to have kids at all, or put it off until retirement. The end of aging changes EVERYTHING about our lives and the world, and genuinely for the better. Imagine how much knowledge has been lost due to old professors and researchers dying off. This will largely put an end to such losses.

about two weeks ago
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Silicon Valley's Quest To Extend Life 'Well Beyond 120'

tmosley Re:Why tech zillionaires fund life exension resear (272 comments)

"Man will never fly!"

We've already created machines that have limited cognition. Just recently a lab group trained a neural net to identify not only objects within a still image, but what was actually going on (ie a picture of a girl playing with a dog was identified as such). This is already PRIMATE LEVEL COGNITION, but in a very limited domain. It just has to be expanded on until we can make one that talks.

http://www.kurzweilai.net/deep...

about two weeks ago
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Silicon Valley's Quest To Extend Life 'Well Beyond 120'

tmosley Re:Why tech zillionaires fund life exension resear (272 comments)

Neuron emulation will likely happen within our lifetime, which would enable uploading, which enables us to escape the creeping grasp of death.

about two weeks ago
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Silicon Valley's Quest To Extend Life 'Well Beyond 120'

tmosley Re:Why tech zillionaires fund life exension resear (272 comments)

Dude, there is a TON of low hanging fruit (hell, I found some myself, which is why I now take niacinamide daily, much cheaper than NAD riboside, but feeds the same set of reactions that increase NAD levels, which seems to be the mechanism that makes calorie restriction extend the lifespan, and I feel FANTASTIC as a result). There has been almost no research into the field. Twenty years ago you could count the lab groups studying aging as such on one fucking hand. Cancer is FAR better understood than aging, even though aging is a very likely cause for most cancers.

There is a lot of reason for optimism here.

about two weeks ago
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Silicon Valley's Quest To Extend Life 'Well Beyond 120'

tmosley Re:How very nice for them. (272 comments)

Yeah, because you know those bastards made the internet and computers and such and just kept it all for themselves. The bastards!

about two weeks ago
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Silicon Valley's Quest To Extend Life 'Well Beyond 120'

tmosley Re:Telemeres (272 comments)

EXACTLY! Telomeres are a cancer control mechanism, and (likely) not much more. Cells (probably) proliferate from stem cells which decline as a side effect of aging. If you could find what causes them to decline, you might be able to wipe out the whole process at once.

about two weeks ago
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Silicon Valley's Quest To Extend Life 'Well Beyond 120'

tmosley Re:The longer you live...Cancer could be your rewa (272 comments)

I guess the second law doesn't apply to naked mole rats. Maybe someone should see if we can make a perpetual motion machine out of them? Or maybe we should learn a little more about thermodynamics before citing them in ways that don't make any sense at all (people who don't age still eat).

about two weeks ago
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Silicon Valley's Quest To Extend Life 'Well Beyond 120'

tmosley Re:The longer you live...Cancer could be your rewa (272 comments)

Cancer isn't random. If it were, incidence would be spread throughout the life rather than being concentrated in the later years of life.

Far more likely (IMO) that cancer is a side effect of aging. We have merely reduced mortality from other diseases (including some other age related disease), which has left more people getting cancer.

I kinda doubt that telomeres are the key to aging. Rather, I think they are strictly a method for preventing cancer. Instead, I think that something is happening to cause a decline in the number of stem cells in the body as you get older, likely something to do with NAD.

about two weeks ago

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