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New Drugs Trail Many Old Ones In Effectiveness Against Disease

wsloand The Real Comparison (230 comments)

While the new drugs are often less effective when compared to themselves, they are usually similarly or more effective when on top of the standard of care. For example, what tends to happen is that in the old studies with diuretics people had a systolic blood pressure going in of 200 mm Hg. Now, people are already on those diuretics and have a systolic blood pressure going in of 150 mm Hg. Given the same drug as a comparison, you often see that either the new drug is better in efficacy or similar in efficacy and better in safety.

about 10 months ago
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MATLAB Can't Manipulate 64-Bit Integers

wsloand Re:Yes but Octave (334 comments)

You should check out some of the newer versions of Octave. The graphics in versions 3.0 and 3.2 are very much improved. (Disclosure: I was an active Octave developer a couple of years ago.)

more than 3 years ago
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How Many Admins Per User/Computer Have You Seen?

wsloand Re:Lockdown (414 comments)

My best experience in managing a moderate sized company was ~400 users where 80-90% of them had thin terminals and only needed about 10 apps. The terminal cost ~$300 each and the maintenance on the terminal was almost nil. If one wasn't working, a local "expert user" put it into a "broken" box and we would take it, reflash it, and if it still didn't work it was replaced. ~2%/yr broke (one every other month).

more than 4 years ago
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How Many Admins Per User/Computer Have You Seen?

wsloand Lockdown (414 comments)

In my experience, it's a function of how well you're doing your job and how locked down you can make the users' systems. If you do your job well and can effectively totally lock down the system (users install nothing, use Citrix, etc, and are only allowed to use a limited number of apps), that can be perfectly reasonable.

more than 4 years ago
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ZFS Gets Built-In Deduplication

wsloand Re:Wake me when they build it into the hard disk (386 comments)

But, the design delays when you would have to buy more disk space. The problem you're referring to is a problem to a specific disk usage scenario. Not all problems are the same, and if you're planning to mass-edit identical files that are a) large enough to make a meaningful impact on your disk usage and b) being edited in a non-uniform way, then don't use the de-duplication feature or plan ahead.

more than 4 years ago
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NASA Opens Space Image Library

wsloand Re:Poor image quality on more recent images (105 comments)

It is not monetary value it's scientific value. Generally the scientist who is has the rights to the telescope time (or who has helped design or run the mission, etc.) has rights to the data for a limited time (I think it's 6 months). After that time the images are released for the (scientific) general public. The difference here is that it's put into a form that the really general public can access the materials.

No reason for paranoia in this case that I'm aware of.

more than 5 years ago

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