The Yubikey can serve as a One-Time-Password(OTP), Universal Second Factor (U2F) Authentication, Etc. I primarily use it for the U2F, which is similar to an RSA Token, but it conveniently eliminates token expiration anxiety, and errors frequently caused by chronic butterfingers. I just jam it into a USB port, it gets recognized as a keyboard, I press the little light on the top, and boom!
The NEO is similar to the standard blue Yubikey, additionally supporting NFC for some protocols. Unfortunately, U2F is NOT supported through the embedded NFC chip. https://www.yubico.com/product...
When I bought mine, I was hoping to use it as a physical password on my smartphone, simply swiping across the back side, as available with the OTP protocol. I later found out that would be forced to use the USB on everything, and have yet to find any use for the NFC with U2F. (my fault for not reading the documentation more thoroughly, as they clearly state: "...current U2F standards do not support NFC for mobile devices.")
Long story short, if you only need the U2F, don't bother with the NEO. just get the cheaper FIDO U2F SPECIAL
As far as durability, its survived me for about a year now, and I'm not known being gentile.